Multivariate pattern analysis of fMRI data for imaginary and real colours in grapheme–colour synaesthesia.
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| Title: | Multivariate pattern analysis of fMRI data for imaginary and real colours in grapheme–colour synaesthesia. |
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| Authors: | Ruiz, Mathieu J. (AUTHOR), Dojat, Michel (AUTHOR), Hupé, Jean‐Michel (AUTHOR) |
| Source: | European Journal of Neuroscience. Sep2020, Vol. 52 Issue 5, p3434-3456. 23p. 2 Color Photographs, 1 Chart, 7 Graphs. |
| Subjects: | Synesthesia, Multivariate analysis, Signal-to-noise ratio, Data analysis, Functional magnetic resonance imaging |
| Abstract: | Grapheme–colour synaesthesia is a subjective phenomenon related to perception and imagination, in which some people involuntarily but systematically associate specific, idiosyncratic colours to achromatic letters or digits. Its investigation is relevant to unravel the neural correlates of colour perception in isolation from low‐level neural processing of spectral components, as well as the neural correlates of imagination by being able to reliably trigger imaginary colour experiences. However, functional MRI studies using univariate analyses failed to provide univocal evidence of the activation of the "colour network" by synaesthesia. Applying multivariate (multivoxel) pattern analysis (MVPA) on 20 synaesthetes and 20 control participants, we tested whether the neural processing of real colours (concentric rings) and synaesthetic colours (black graphemes) shared patterns of activations. Region of interest analyses in retinotopically and anatomically defined visual areas revealed neither evidence of shared circuits for real and synaesthetic colour processing, nor processing difference between synaesthetes and controls. We also found no correlation with individual experiences, characterised by measuring the strength of synaesthetic associations. The whole brain searchlight analysis led to similar results. We conclude that revealing the neural coding of the synaesthetic experience of colours is a hard task which requires the improvement of our current methodology: for example involving more individuals and achieving higher MR signal to noise ratio and spatial resolution. So far, we have not found any evidence of the involvement of the cortical colour network in the subjective experience of synaesthetic colours. [ABSTRACT FROM AUTHOR] |
| Copyright of European Journal of Neuroscience is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 147889659 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Multivariate pattern analysis of fMRI data for imaginary and real colours in grapheme–colour synaesthesia. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Ruiz%2C+Mathieu+J%2E%22">Ruiz, Mathieu J.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Dojat%2C+Michel%22">Dojat, Michel</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Hupé%2C+Jean‐Michel%22">Hupé, Jean‐Michel</searchLink> (AUTHOR) – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22European+Journal+of+Neuroscience%22">European Journal of Neuroscience</searchLink>. Sep2020, Vol. 52 Issue 5, p3434-3456. 23p. 2 Color Photographs, 1 Chart, 7 Graphs. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Synesthesia%22">Synesthesia</searchLink><br /><searchLink fieldCode="DE" term="%22Multivariate+analysis%22">Multivariate analysis</searchLink><br /><searchLink fieldCode="DE" term="%22Signal-to-noise+ratio%22">Signal-to-noise ratio</searchLink><br /><searchLink fieldCode="DE" term="%22Data+analysis%22">Data analysis</searchLink><br /><searchLink fieldCode="DE" term="%22Functional+magnetic+resonance+imaging%22">Functional magnetic resonance imaging</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Grapheme–colour synaesthesia is a subjective phenomenon related to perception and imagination, in which some people involuntarily but systematically associate specific, idiosyncratic colours to achromatic letters or digits. Its investigation is relevant to unravel the neural correlates of colour perception in isolation from low‐level neural processing of spectral components, as well as the neural correlates of imagination by being able to reliably trigger imaginary colour experiences. However, functional MRI studies using univariate analyses failed to provide univocal evidence of the activation of the "colour network" by synaesthesia. Applying multivariate (multivoxel) pattern analysis (MVPA) on 20 synaesthetes and 20 control participants, we tested whether the neural processing of real colours (concentric rings) and synaesthetic colours (black graphemes) shared patterns of activations. Region of interest analyses in retinotopically and anatomically defined visual areas revealed neither evidence of shared circuits for real and synaesthetic colour processing, nor processing difference between synaesthetes and controls. We also found no correlation with individual experiences, characterised by measuring the strength of synaesthetic associations. The whole brain searchlight analysis led to similar results. We conclude that revealing the neural coding of the synaesthetic experience of colours is a hard task which requires the improvement of our current methodology: for example involving more individuals and achieving higher MR signal to noise ratio and spatial resolution. So far, we have not found any evidence of the involvement of the cortical colour network in the subjective experience of synaesthetic colours. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of European Journal of Neuroscience is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1111/ejn.14774 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 23 StartPage: 3434 Subjects: – SubjectFull: Synesthesia Type: general – SubjectFull: Multivariate analysis Type: general – SubjectFull: Signal-to-noise ratio Type: general – SubjectFull: Data analysis Type: general – SubjectFull: Functional magnetic resonance imaging Type: general Titles: – TitleFull: Multivariate pattern analysis of fMRI data for imaginary and real colours in grapheme–colour synaesthesia. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Ruiz, Mathieu J. – PersonEntity: Name: NameFull: Dojat, Michel – PersonEntity: Name: NameFull: Hupé, Jean‐Michel IsPartOfRelationships: – BibEntity: Dates: – D: 15 M: 09 Text: Sep2020 Type: published Y: 2020 Identifiers: – Type: issn-print Value: 0953816X Numbering: – Type: volume Value: 52 – Type: issue Value: 5 Titles: – TitleFull: European Journal of Neuroscience Type: main |
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