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Influence of social cognition as a mediator between cognitive reserve and psychosocial functioning in patients with first episode psychosis.

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Title: Influence of social cognition as a mediator between cognitive reserve and psychosocial functioning in patients with first episode psychosis.
Authors: González-Ortega, I, González-Pinto, A, Alberich, S, Echeburúa, E, Bernardo, M, Cabrera, B, Amoretti, S, Lobo, A, Arango, C, Corripio, I, Vieta, E, de la Serna, E, Rodriguez-Jimenez, R, Segarra, R, López-Ilundain, JM, Sánchez-Torres, AM, Cuesta, MJ, Zorrilla, I, López, P, Bioque, M
Source: Psychological Medicine. Dec2020, Vol. 50 Issue 6, p2702-2710. 9p.
Subjects: Cognitive testing, Factor analysis, Neuropsychological tests, Psychoses, Social perception, T-test (Statistics), Multiple regression analysis, Socioeconomic factors, Descriptive statistics
Abstract: Background: Social cognition has been associated with functional outcome in patients with first episode psychosis (FEP). Social cognition has also been associated with neurocognition and cognitive reserve. Although cognitive reserve, neurocognitive functioning, social cognition, and functional outcome are related, the direction of their associations is not clear. Therefore, the main aim of this study was to analyze the influence of social cognition as a mediator between cognitive reserve and cognitive domains on functioning in FEP both at baseline and at 2 years. Methods: The sample of the study was composed of 282 FEP patients followed up for 2 years. To analyze whether social cognition mediates the influence of cognitive reserve and cognitive domains on functioning, a path analysis was performed. The statistical significance of any mediation effects was evaluated by bootstrap analysis. Results: At baseline, as neither cognitive reserve nor the cognitive domains studied were related to functioning, the conditions for mediation were not satisfied. Nevertheless, at 2 years of follow-up, social cognition acted as a mediator between cognitive reserve and functioning. Likewise, social cognition was a mediator between verbal memory and functional outcome. The results of the bootstrap analysis confirmed these significant mediations (95% bootstrapped CI (−10.215 to −0.337) and (−4.731 to −0.605) respectively). Conclusions: Cognitive reserve and neurocognition are related to functioning, and social cognition mediates in this relationship. [ABSTRACT FROM AUTHOR]
Copyright of Psychological Medicine is the property of Cambridge University Press and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Influence of social cognition as a mediator between cognitive reserve and psychosocial functioning in patients with first episode psychosis.
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  Data: <searchLink fieldCode="AR" term="%22González-Ortega%2C+I%22">González-Ortega, I</searchLink><br /><searchLink fieldCode="AR" term="%22González-Pinto%2C+A%22">González-Pinto, A</searchLink><br /><searchLink fieldCode="AR" term="%22Alberich%2C+S%22">Alberich, S</searchLink><br /><searchLink fieldCode="AR" term="%22Echeburúa%2C+E%22">Echeburúa, E</searchLink><br /><searchLink fieldCode="AR" term="%22Bernardo%2C+M%22">Bernardo, M</searchLink><br /><searchLink fieldCode="AR" term="%22Cabrera%2C+B%22">Cabrera, B</searchLink><br /><searchLink fieldCode="AR" term="%22Amoretti%2C+S%22">Amoretti, S</searchLink><br /><searchLink fieldCode="AR" term="%22Lobo%2C+A%22">Lobo, A</searchLink><br /><searchLink fieldCode="AR" term="%22Arango%2C+C%22">Arango, C</searchLink><br /><searchLink fieldCode="AR" term="%22Corripio%2C+I%22">Corripio, I</searchLink><br /><searchLink fieldCode="AR" term="%22Vieta%2C+E%22">Vieta, E</searchLink><br /><searchLink fieldCode="AR" term="%22de+la+Serna%2C+E%22">de la Serna, E</searchLink><br /><searchLink fieldCode="AR" term="%22Rodriguez-Jimenez%2C+R%22">Rodriguez-Jimenez, R</searchLink><br /><searchLink fieldCode="AR" term="%22Segarra%2C+R%22">Segarra, R</searchLink><br /><searchLink fieldCode="AR" term="%22López-Ilundain%2C+JM%22">López-Ilundain, JM</searchLink><br /><searchLink fieldCode="AR" term="%22Sánchez-Torres%2C+AM%22">Sánchez-Torres, AM</searchLink><br /><searchLink fieldCode="AR" term="%22Cuesta%2C+MJ%22">Cuesta, MJ</searchLink><br /><searchLink fieldCode="AR" term="%22Zorrilla%2C+I%22">Zorrilla, I</searchLink><br /><searchLink fieldCode="AR" term="%22López%2C+P%22">López, P</searchLink><br /><searchLink fieldCode="AR" term="%22Bioque%2C+M%22">Bioque, M</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22Psychological+Medicine%22">Psychological Medicine</searchLink>. Dec2020, Vol. 50 Issue 6, p2702-2710. 9p.
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  Data: <searchLink fieldCode="DE" term="%22Cognitive+testing%22">Cognitive testing</searchLink><br /><searchLink fieldCode="DE" term="%22Factor+analysis%22">Factor analysis</searchLink><br /><searchLink fieldCode="DE" term="%22Neuropsychological+tests%22">Neuropsychological tests</searchLink><br /><searchLink fieldCode="DE" term="%22Psychoses%22">Psychoses</searchLink><br /><searchLink fieldCode="DE" term="%22Social+perception%22">Social perception</searchLink><br /><searchLink fieldCode="DE" term="%22T-test+%28Statistics%29%22">T-test (Statistics)</searchLink><br /><searchLink fieldCode="DE" term="%22Multiple+regression+analysis%22">Multiple regression analysis</searchLink><br /><searchLink fieldCode="DE" term="%22Socioeconomic+factors%22">Socioeconomic factors</searchLink><br /><searchLink fieldCode="DE" term="%22Descriptive+statistics%22">Descriptive statistics</searchLink>
– Name: Abstract
  Label: Abstract
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  Data: Background: Social cognition has been associated with functional outcome in patients with first episode psychosis (FEP). Social cognition has also been associated with neurocognition and cognitive reserve. Although cognitive reserve, neurocognitive functioning, social cognition, and functional outcome are related, the direction of their associations is not clear. Therefore, the main aim of this study was to analyze the influence of social cognition as a mediator between cognitive reserve and cognitive domains on functioning in FEP both at baseline and at 2 years. Methods: The sample of the study was composed of 282 FEP patients followed up for 2 years. To analyze whether social cognition mediates the influence of cognitive reserve and cognitive domains on functioning, a path analysis was performed. The statistical significance of any mediation effects was evaluated by bootstrap analysis. Results: At baseline, as neither cognitive reserve nor the cognitive domains studied were related to functioning, the conditions for mediation were not satisfied. Nevertheless, at 2 years of follow-up, social cognition acted as a mediator between cognitive reserve and functioning. Likewise, social cognition was a mediator between verbal memory and functional outcome. The results of the bootstrap analysis confirmed these significant mediations (95% bootstrapped CI (−10.215 to −0.337) and (−4.731 to −0.605) respectively). Conclusions: Cognitive reserve and neurocognition are related to functioning, and social cognition mediates in this relationship. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Psychological Medicine is the property of Cambridge University Press and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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