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High-intensity functional exercise in older adults with dementia: A systematic review and meta-analysis.

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Title: High-intensity functional exercise in older adults with dementia: A systematic review and meta-analysis.
Authors: Yeh, Shu-Wei, Lin, Li-Fong, Chen, Hung-Chou, Huang, Li-Kai, Hu, Chaur-Jong, Tam, Ka-Wai, Kuan, Yi-Chun, Hong, Chien-Hsiung
Source: Clinical Rehabilitation. Feb2021, Vol. 35 Issue 2, p169-181. 13p.
Subjects: Cognition, Confidence intervals, Dementia patients, Mental depression, Postural balance, Exercise therapy, Gait in humans, Information storage & retrieval systems, Medical databases, Medical information storage & retrieval systems, MEDLINE, Meta-analysis, Online information services, Senile dementia, Systematic reviews, Activities of daily living, Well-being, Exercise intensity, High-intensity interval training, Old age
Abstract: Objective: This study aimed to investigate the efficacy of high-intensity functional exercise among older adults with dementia. Methods: In this systematic review and meta-analysis of randomized controlled trials, we collected articles published before August 2020 from PubMed, Embase, and the Cochrane Library to evaluate the effect of high-intensity functional exercise on older adults with dementia. Primary outcomes included improvements in balance function and gait performance (speed, cadence, and stride length). The secondary outcomes included lower limb strength, activities of daily living, psychiatric well-being, depression, and cognition. Furthermore, we performed subgroup analysis with two high-intensity functional exercise programs: the Umeå program and Hauer's program. Results: We identified 15 articles describing six trials including older adults with dementia undergoing high-intensity functional exercise or control activity. The meta-analysis indicated that high-intensity functional exercise, both in Hauer's program and in the Umeå program, significantly improved balance function (pooled standardized mean difference 0.57, 95% confidence interval 0.31–0.83). Hauer's program significantly improved gait speed, cadence, stride length, and lower limb strength. Beneficial effects on speed, cadence, and lower limb strength were retained for several months. The Umeå program facilitated activities of daily living and psychiatric well-being, with effects on activities of daily living lasting several months. In the only eligible trial, no effects on cognition were observed. Adverse effects of high-intensity functional exercise were minimal to none. Conclusions: High-intensity functional exercise is generally safe and is recommended for older individuals with mild or moderate dementia to provide benefits in motor performance and daily functioning. [ABSTRACT FROM AUTHOR]
Copyright of Clinical Rehabilitation is the property of Sage Publications Inc. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: High-intensity functional exercise in older adults with dementia: A systematic review and meta-analysis.
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  Data: <searchLink fieldCode="AR" term="%22Yeh%2C+Shu-Wei%22">Yeh, Shu-Wei</searchLink><br /><searchLink fieldCode="AR" term="%22Lin%2C+Li-Fong%22">Lin, Li-Fong</searchLink><br /><searchLink fieldCode="AR" term="%22Chen%2C+Hung-Chou%22">Chen, Hung-Chou</searchLink><br /><searchLink fieldCode="AR" term="%22Huang%2C+Li-Kai%22">Huang, Li-Kai</searchLink><br /><searchLink fieldCode="AR" term="%22Hu%2C+Chaur-Jong%22">Hu, Chaur-Jong</searchLink><br /><searchLink fieldCode="AR" term="%22Tam%2C+Ka-Wai%22">Tam, Ka-Wai</searchLink><br /><searchLink fieldCode="AR" term="%22Kuan%2C+Yi-Chun%22">Kuan, Yi-Chun</searchLink><br /><searchLink fieldCode="AR" term="%22Hong%2C+Chien-Hsiung%22">Hong, Chien-Hsiung</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22Clinical+Rehabilitation%22">Clinical Rehabilitation</searchLink>. Feb2021, Vol. 35 Issue 2, p169-181. 13p.
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  Data: <searchLink fieldCode="DE" term="%22Cognition%22">Cognition</searchLink><br /><searchLink fieldCode="DE" term="%22Confidence+intervals%22">Confidence intervals</searchLink><br /><searchLink fieldCode="DE" term="%22Dementia+patients%22">Dementia patients</searchLink><br /><searchLink fieldCode="DE" term="%22Mental+depression%22">Mental depression</searchLink><br /><searchLink fieldCode="DE" term="%22Postural+balance%22">Postural balance</searchLink><br /><searchLink fieldCode="DE" term="%22Exercise+therapy%22">Exercise therapy</searchLink><br /><searchLink fieldCode="DE" term="%22Gait+in+humans%22">Gait in humans</searchLink><br /><searchLink fieldCode="DE" term="%22Information+storage+%26+retrieval+systems%22">Information storage & retrieval systems</searchLink><br /><searchLink fieldCode="DE" term="%22Medical+databases%22">Medical databases</searchLink><br /><searchLink fieldCode="DE" term="%22Medical+information+storage+%26+retrieval+systems%22">Medical information storage & retrieval systems</searchLink><br /><searchLink fieldCode="DE" term="%22MEDLINE%22">MEDLINE</searchLink><br /><searchLink fieldCode="DE" term="%22Meta-analysis%22">Meta-analysis</searchLink><br /><searchLink fieldCode="DE" term="%22Online+information+services%22">Online information services</searchLink><br /><searchLink fieldCode="DE" term="%22Senile+dementia%22">Senile dementia</searchLink><br /><searchLink fieldCode="DE" term="%22Systematic+reviews%22">Systematic reviews</searchLink><br /><searchLink fieldCode="DE" term="%22Activities+of+daily+living%22">Activities of daily living</searchLink><br /><searchLink fieldCode="DE" term="%22Well-being%22">Well-being</searchLink><br /><searchLink fieldCode="DE" term="%22Exercise+intensity%22">Exercise intensity</searchLink><br /><searchLink fieldCode="DE" term="%22High-intensity+interval+training%22">High-intensity interval training</searchLink><br /><searchLink fieldCode="DE" term="%22Old+age%22">Old age</searchLink>
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  Label: Abstract
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  Data: Objective: This study aimed to investigate the efficacy of high-intensity functional exercise among older adults with dementia. Methods: In this systematic review and meta-analysis of randomized controlled trials, we collected articles published before August 2020 from PubMed, Embase, and the Cochrane Library to evaluate the effect of high-intensity functional exercise on older adults with dementia. Primary outcomes included improvements in balance function and gait performance (speed, cadence, and stride length). The secondary outcomes included lower limb strength, activities of daily living, psychiatric well-being, depression, and cognition. Furthermore, we performed subgroup analysis with two high-intensity functional exercise programs: the Umeå program and Hauer's program. Results: We identified 15 articles describing six trials including older adults with dementia undergoing high-intensity functional exercise or control activity. The meta-analysis indicated that high-intensity functional exercise, both in Hauer's program and in the Umeå program, significantly improved balance function (pooled standardized mean difference 0.57, 95% confidence interval 0.31–0.83). Hauer's program significantly improved gait speed, cadence, stride length, and lower limb strength. Beneficial effects on speed, cadence, and lower limb strength were retained for several months. The Umeå program facilitated activities of daily living and psychiatric well-being, with effects on activities of daily living lasting several months. In the only eligible trial, no effects on cognition were observed. Adverse effects of high-intensity functional exercise were minimal to none. Conclusions: High-intensity functional exercise is generally safe and is recommended for older individuals with mild or moderate dementia to provide benefits in motor performance and daily functioning. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Clinical Rehabilitation is the property of Sage Publications Inc. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Value: 10.1177/0269215520961637
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        Text: English
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      – SubjectFull: Cognition
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      – SubjectFull: Confidence intervals
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      – SubjectFull: Dementia patients
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      – TitleFull: High-intensity functional exercise in older adults with dementia: A systematic review and meta-analysis.
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              Text: Feb2021
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