Why Switch? - Motivations for Self-Substitution of Illegal Drugs.

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Title: Why Switch? - Motivations for Self-Substitution of Illegal Drugs.
Authors: Shapira, Barak (AUTHOR), Berkovitz, Ronny (AUTHOR), Rosca, Paola (AUTHOR), Lev-Ran, Shaul (AUTHOR), Kaptsan, Alexander (AUTHOR), Neumark, Yehuda (AUTHOR)
Source: Substance Use & Misuse. 2021, Vol. 56 Issue 5, p627-638. 12p. 1 Diagram, 3 Charts, 1 Graph.
Subjects: Substance abuse, Generic drug substitution, Confidence intervals, Cannabis (Genus), Psychiatric drugs, Motivation (Psychology), Cross-sectional method, Psychology of drug abusers, Age distribution, Drug withdrawal symptoms, Patients, Hospital admission & discharge, Descriptive statistics, Drugs of abuse, Odds ratio, Heroin
Abstract: Self-substitution is the conscious switch from one drug to another for reasons such as price, availability, desired effect, or perceived benefit of the substitute drug. Purpose/Objectives: This study aimed to describe drug use patterns and motivations associated with substitution. We examined correlates of lifetime substitution among individuals with substance use disorder. Methods: A cross-sectional study of 771 treatment-enrolled individuals. We used self-report for determining the lifetime prevalence, correlates, and motivations for substitution. Results: Of the 771 respondents, 570 (73.9%) reported ever substituting their preferred substance. The main incentives for substitution were availability (23.7%) and curiosity (20.2%). Among heroin or cannabis preferers, improved effects or less adverse effects of the substitute drug, self-medication, and managing withdrawal symptoms were significant substitution incentives. Increased odds for substitution were observed for past 12 months use of cannabis (OR = 1.51, CI = 1.06-4.52), prescription opioids (OR = 2.86, CI = 1.81-4.52), novel psychoactive substances (OR = 2.68, CI = 1.64-4.36), and repeated admission (OR = 1.50, CI = 1.05-2.14). Older age at onset-of-use was negatively associated with substitution (OR = 0.95, CI = 0.93-0.98). Conclusions: Self-substitution of one substance for another is a highly prevalent behavior among treatment-enrolled patients with substance use disorder. Clinicians caring for substance use disorder patients should be aware of substitution patterns involving the use of highly potent substances, which constitutes a risk to patients. Results underscore the benefit of substitution patterns analyses, as they reveal important information on the characteristics of persons who use drugs and their motivations. [ABSTRACT FROM AUTHOR]
Copyright of Substance Use & Misuse is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Why Switch? - Motivations for Self-Substitution of Illegal Drugs.
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  Label: Authors
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  Data: <searchLink fieldCode="AR" term="%22Shapira%2C+Barak%22">Shapira, Barak</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Berkovitz%2C+Ronny%22">Berkovitz, Ronny</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Rosca%2C+Paola%22">Rosca, Paola</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Lev-Ran%2C+Shaul%22">Lev-Ran, Shaul</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kaptsan%2C+Alexander%22">Kaptsan, Alexander</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Neumark%2C+Yehuda%22">Neumark, Yehuda</searchLink> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22Substance+Use+%26+Misuse%22">Substance Use & Misuse</searchLink>. 2021, Vol. 56 Issue 5, p627-638. 12p. 1 Diagram, 3 Charts, 1 Graph.
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  Data: <searchLink fieldCode="DE" term="%22Substance+abuse%22">Substance abuse</searchLink><br /><searchLink fieldCode="DE" term="%22Generic+drug+substitution%22">Generic drug substitution</searchLink><br /><searchLink fieldCode="DE" term="%22Confidence+intervals%22">Confidence intervals</searchLink><br /><searchLink fieldCode="DE" term="%22Cannabis+%28Genus%29%22">Cannabis (Genus)</searchLink><br /><searchLink fieldCode="DE" term="%22Psychiatric+drugs%22">Psychiatric drugs</searchLink><br /><searchLink fieldCode="DE" term="%22Motivation+%28Psychology%29%22">Motivation (Psychology)</searchLink><br /><searchLink fieldCode="DE" term="%22Cross-sectional+method%22">Cross-sectional method</searchLink><br /><searchLink fieldCode="DE" term="%22Psychology+of+drug+abusers%22">Psychology of drug abusers</searchLink><br /><searchLink fieldCode="DE" term="%22Age+distribution%22">Age distribution</searchLink><br /><searchLink fieldCode="DE" term="%22Drug+withdrawal+symptoms%22">Drug withdrawal symptoms</searchLink><br /><searchLink fieldCode="DE" term="%22Patients%22">Patients</searchLink><br /><searchLink fieldCode="DE" term="%22Hospital+admission+%26+discharge%22">Hospital admission & discharge</searchLink><br /><searchLink fieldCode="DE" term="%22Descriptive+statistics%22">Descriptive statistics</searchLink><br /><searchLink fieldCode="DE" term="%22Drugs+of+abuse%22">Drugs of abuse</searchLink><br /><searchLink fieldCode="DE" term="%22Odds+ratio%22">Odds ratio</searchLink><br /><searchLink fieldCode="DE" term="%22Heroin%22">Heroin</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Self-substitution is the conscious switch from one drug to another for reasons such as price, availability, desired effect, or perceived benefit of the substitute drug. Purpose/Objectives: This study aimed to describe drug use patterns and motivations associated with substitution. We examined correlates of lifetime substitution among individuals with substance use disorder. Methods: A cross-sectional study of 771 treatment-enrolled individuals. We used self-report for determining the lifetime prevalence, correlates, and motivations for substitution. Results: Of the 771 respondents, 570 (73.9%) reported ever substituting their preferred substance. The main incentives for substitution were availability (23.7%) and curiosity (20.2%). Among heroin or cannabis preferers, improved effects or less adverse effects of the substitute drug, self-medication, and managing withdrawal symptoms were significant substitution incentives. Increased odds for substitution were observed for past 12 months use of cannabis (OR = 1.51, CI = 1.06-4.52), prescription opioids (OR = 2.86, CI = 1.81-4.52), novel psychoactive substances (OR = 2.68, CI = 1.64-4.36), and repeated admission (OR = 1.50, CI = 1.05-2.14). Older age at onset-of-use was negatively associated with substitution (OR = 0.95, CI = 0.93-0.98). Conclusions: Self-substitution of one substance for another is a highly prevalent behavior among treatment-enrolled patients with substance use disorder. Clinicians caring for substance use disorder patients should be aware of substitution patterns involving the use of highly potent substances, which constitutes a risk to patients. Results underscore the benefit of substitution patterns analyses, as they reveal important information on the characteristics of persons who use drugs and their motivations. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Substance Use & Misuse is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1080/10826084.2021.1887246
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 12
        StartPage: 627
    Subjects:
      – SubjectFull: Substance abuse
        Type: general
      – SubjectFull: Generic drug substitution
        Type: general
      – SubjectFull: Confidence intervals
        Type: general
      – SubjectFull: Cannabis (Genus)
        Type: general
      – SubjectFull: Psychiatric drugs
        Type: general
      – SubjectFull: Motivation (Psychology)
        Type: general
      – SubjectFull: Cross-sectional method
        Type: general
      – SubjectFull: Psychology of drug abusers
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      – SubjectFull: Age distribution
        Type: general
      – SubjectFull: Drug withdrawal symptoms
        Type: general
      – SubjectFull: Patients
        Type: general
      – SubjectFull: Hospital admission & discharge
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      – SubjectFull: Drugs of abuse
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      – SubjectFull: Odds ratio
        Type: general
      – SubjectFull: Heroin
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    Titles:
      – TitleFull: Why Switch? - Motivations for Self-Substitution of Illegal Drugs.
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            NameFull: Lev-Ran, Shaul
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              Text: 2021
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              Y: 2021
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