View in EDS HTML Full Text PDF Full Text

Clonal evolution and supratentorial dissemination of a spinal cord glioma.

Saved in:
Bibliographic Details
Title: Clonal evolution and supratentorial dissemination of a spinal cord glioma.
Authors: Kong, Ziren (AUTHOR), Chen, Wenlin (AUTHOR), Zhao, Dachun (AUTHOR), Wang, Yu (AUTHOR), Ma, Wenbin (AUTHOR)
Source: Neurological Sciences. May2021, Vol. 42 Issue 5, p2137-2141. 5p. 2 Color Photographs, 1 Diagram.
Subjects: Spinal cord, Magnetic resonance imaging, Gliomas
Abstract: Consistent with the features of spinal cord glioma, the original and disseminated tumor did not exhibit an IDH1/2 mutation [[1]]; however, representative characteristics such as BRAF and H3F3A/B variations were also absent in the spinal cord tumor [[1], [3]]. In addition, the MYC pathway was activated in all 4 tumors, and Hippo stimulation also occurred in the cavernous tumor, both of which are less frequently reported but may facilitate tumor progression. Glioma infiltration with necrosis of the temporal lobe, midbrain, brain stem, and part of the medulla oblongata was visible under microscopy, and tumor infiltration at the C3 level was also noted. It was relatively independent from the other subclonal clusters, which may be due to a dissemination from the spinal tumor to the pontine and temporal tumors after the appearance of the temporal lesion The chromosomal alterations increased as the tumor evolved (Fig. [Extracted from the article]
Copyright of Neurological Sciences is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: pbh
DbLabel: Psychology and Behavioral Sciences Collection
An: 149788799
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Clonal evolution and supratentorial dissemination of a spinal cord glioma.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Kong%2C+Ziren%22">Kong, Ziren</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Chen%2C+Wenlin%22">Chen, Wenlin</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Zhao%2C+Dachun%22">Zhao, Dachun</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Wang%2C+Yu%22">Wang, Yu</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Ma%2C+Wenbin%22">Ma, Wenbin</searchLink> (AUTHOR)
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22Neurological+Sciences%22">Neurological Sciences</searchLink>. May2021, Vol. 42 Issue 5, p2137-2141. 5p. 2 Color Photographs, 1 Diagram.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Spinal+cord%22">Spinal cord</searchLink><br /><searchLink fieldCode="DE" term="%22Magnetic+resonance+imaging%22">Magnetic resonance imaging</searchLink><br /><searchLink fieldCode="DE" term="%22Gliomas%22">Gliomas</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Consistent with the features of spinal cord glioma, the original and disseminated tumor did not exhibit an IDH1/2 mutation [[1]]; however, representative characteristics such as BRAF and H3F3A/B variations were also absent in the spinal cord tumor [[1], [3]]. In addition, the MYC pathway was activated in all 4 tumors, and Hippo stimulation also occurred in the cavernous tumor, both of which are less frequently reported but may facilitate tumor progression. Glioma infiltration with necrosis of the temporal lobe, midbrain, brain stem, and part of the medulla oblongata was visible under microscopy, and tumor infiltration at the C3 level was also noted. It was relatively independent from the other subclonal clusters, which may be due to a dissemination from the spinal tumor to the pontine and temporal tumors after the appearance of the temporal lesion The chromosomal alterations increased as the tumor evolved (Fig. [Extracted from the article]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Neurological Sciences is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=149788799
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1007/s10072-020-04924-2
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 5
        StartPage: 2137
    Subjects:
      – SubjectFull: Spinal cord
        Type: general
      – SubjectFull: Magnetic resonance imaging
        Type: general
      – SubjectFull: Gliomas
        Type: general
    Titles:
      – TitleFull: Clonal evolution and supratentorial dissemination of a spinal cord glioma.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Kong, Ziren
      – PersonEntity:
          Name:
            NameFull: Chen, Wenlin
      – PersonEntity:
          Name:
            NameFull: Zhao, Dachun
      – PersonEntity:
          Name:
            NameFull: Wang, Yu
      – PersonEntity:
          Name:
            NameFull: Ma, Wenbin
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 05
              Text: May2021
              Type: published
              Y: 2021
          Identifiers:
            – Type: issn-print
              Value: 15901874
          Numbering:
            – Type: volume
              Value: 42
            – Type: issue
              Value: 5
          Titles:
            – TitleFull: Neurological Sciences
              Type: main
ResultId 1