Beyond abstinence and relapse II: momentary relationships between stress, craving, and lapse within clusters of patients with similar patterns of drug use.
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| Title: | Beyond abstinence and relapse II: momentary relationships between stress, craving, and lapse within clusters of patients with similar patterns of drug use. |
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| Authors: | Panlilio, Leigh V. (AUTHOR), Stull, Samuel W. (AUTHOR), Bertz, Jeremiah W. (AUTHOR), Burgess-Hull, Albert J. (AUTHOR), Lanza, Stephanie T. (AUTHOR), Curtis, Brenda L. (AUTHOR), Phillips, Karran A. (AUTHOR), Epstein, David H. (AUTHOR), Preston, Kenzie L. (AUTHOR) |
| Source: | Psychopharmacology. Jun2021, Vol. 238 Issue 6, p1513-1529. 17p. 5 Graphs. |
| Subjects: | Buprenorphine, Drug abstinence, Drug utilization, Desire, Hierarchical clustering (Cluster analysis), Ecological momentary assessments (Clinical psychology), Substance-induced disorders, Opioid abuse |
| Abstract: | Rationale: Given that many patients being treated for opioid-use disorder continue to use drugs, identifying clusters of patients who share similar patterns of use might provide insight into the disorder, the processes that affect it, and ways that treatment can be personalized. Objectives and methods: We applied hierarchical clustering to identify patterns of opioid and cocaine use in 309 participants being treated with methadone or buprenorphine (in a buprenorphine–naloxone formulation) for up to 16 weeks. A smartphone app was used to assess stress and craving at three random times per day over the course of the study. Results: Five basic patterns of use were identified: frequent opioid use, frequent cocaine use, frequent dual use (opioids and cocaine), sporadic use, and infrequent use. These patterns were differentially associated with medication (methadone vs. buprenorphine), race, age, drug-use history, drug-related problems prior to the study, stress-coping strategies, specific triggers of use events, and levels of cue exposure, craving, and negative mood. Craving tended to increase before use in all except those who used sporadically. Craving was sharply higher during the 90 min following moderate-to-severe stress in those with frequent use, but only moderately higher in those with infrequent or sporadic use. Conclusions: People who share similar patterns of drug-use during treatment also tend to share similarities with respect to psychological processes that surround instances of use, such as stress-induced craving. Cluster analysis combined with smartphone-based experience sampling provides an effective strategy for studying how drug use is related to personal and environmental factors. [ABSTRACT FROM AUTHOR] |
| Copyright of Psychopharmacology is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 150429670 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=150429670 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s00213-021-05782-2 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 17 StartPage: 1513 Subjects: – SubjectFull: Buprenorphine Type: general – SubjectFull: Drug abstinence Type: general – SubjectFull: Drug utilization Type: general – SubjectFull: Desire Type: general – SubjectFull: Hierarchical clustering (Cluster analysis) Type: general – SubjectFull: Ecological momentary assessments (Clinical psychology) Type: general – SubjectFull: Substance-induced disorders Type: general – SubjectFull: Opioid abuse Type: general Titles: – TitleFull: Beyond abstinence and relapse II: momentary relationships between stress, craving, and lapse within clusters of patients with similar patterns of drug use. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Panlilio, Leigh V. – PersonEntity: Name: NameFull: Stull, Samuel W. – PersonEntity: Name: NameFull: Bertz, Jeremiah W. – PersonEntity: Name: NameFull: Burgess-Hull, Albert J. – PersonEntity: Name: NameFull: Lanza, Stephanie T. – PersonEntity: Name: NameFull: Curtis, Brenda L. – PersonEntity: Name: NameFull: Phillips, Karran A. – PersonEntity: Name: NameFull: Epstein, David H. – PersonEntity: Name: NameFull: Preston, Kenzie L. IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 06 Text: Jun2021 Type: published Y: 2021 Identifiers: – Type: issn-print Value: 00333158 Numbering: – Type: volume Value: 238 – Type: issue Value: 6 Titles: – TitleFull: Psychopharmacology Type: main |
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