Noncanonical crRNAs derived from host transcripts enable multiplexable RNA detection by Cas9. - Jiao, Chunlei; Sharma, Sahil; Dugar, Gaurav; Peeck, Natalia L.; Bischler, Thorsten; Wimmer, Franziska; Yu, Yanying; Barquist, Lars; Schoen, Christoph; Kurzai, Oliver; Sharma, Cynthia M.; Beisel, Chase L. (Science (pre-March 2025), 2021)