View in EDS HTML Full Text PDF Full Text

Association between opioid agonist therapy use and HIV testing uptake among people who have recently injected drugs: a systematic review and meta‐analysis.

Saved in:
Bibliographic Details
Title: Association between opioid agonist therapy use and HIV testing uptake among people who have recently injected drugs: a systematic review and meta‐analysis.
Authors: Ferraro, Claire F. (AUTHOR), Stewart, Daniel E. (AUTHOR), Grebely, Jason (AUTHOR), Tran, Lucy T. (AUTHOR), Zhou, Shally (AUTHOR), Puca, Carla (AUTHOR), Hajarizadeh, Behzad (AUTHOR), Larney, Sarah (AUTHOR), Santo, Thomas (AUTHOR), Higgins, Julian P. T. (AUTHOR), Vickerman, Peter (AUTHOR), Degenhardt, Louisa (AUTHOR), Hickman, Matthew (AUTHOR), French, Clare E. (AUTHOR)
Source: Addiction. Jul2021, Vol. 116 Issue 7, p1664-1676. 13p. 3 Diagrams, 2 Charts, 2 Graphs.
Subjects: Therapeutic use of narcotics, Diagnosis of HIV infections, Substance abuse, Meta-analysis, Analgesics, Systematic reviews, Buprenorphine, Medical screening, Methadone hydrochloride
Abstract: Background and aim: Globally, nearly one in five people who inject drugs (PWID) are living with HIV, and the rate of new HIV infections in PWID is increasing in some settings. Early diagnosis is crucial for effective HIV control. We reviewed the evidence on the association between opioid agonist therapy (OAT) and HIV testing uptake among PWID. Methods: We conducted a systematic review searching MEDLINE, Scopus, Web of Science, Cochrane Central Register of Controlled Trials and PsycINFO for studies published from January 2000 to March 2019. Reference lists and conference proceedings were hand‐searched. Observational and intervention studies were eligible for inclusion. Risk of bias was assessed using the Risk of Bias in Non‐Randomised Studies of Interventions (ROBINS‐I) tool. Meta‐analyses were conducted using random‐effects models. Results: Of 13 373 records identified, 11 studies from Australia, Europe, Malaysia and the United States were included. All studies had at least a serious risk of bias, largely due to confounding and selection bias, making it difficult to draw causal conclusions from the evidence. Ten studies provided data on the association between current OAT use and recent HIV testing. Six showed a positive association, while four provided little evidence of an association: pooled odds ratio (OR) = 1.71, 95% confidence interval (CI) = 1.28–2.27. Looking at having ever been on OAT and having ever been HIV tested, seven studies showed a positive association and three showed either weak or no evidence of an association: pooled OR = 3.82, 95% CI = 2.96–4.95. Conclusions: Opioid agonist therapy may increase uptake of HIV testing among people who inject drugs, providing further evidence that opioid agonist therapy improves the HIV treatment care cascade. [ABSTRACT FROM AUTHOR]
Copyright of Addiction is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: pbh
DbLabel: Psychology and Behavioral Sciences Collection
An: 150671468
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Association between opioid agonist therapy use and HIV testing uptake among people who have recently injected drugs: a systematic review and meta‐analysis.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Ferraro%2C+Claire+F%2E%22">Ferraro, Claire F.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Stewart%2C+Daniel+E%2E%22">Stewart, Daniel E.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Grebely%2C+Jason%22">Grebely, Jason</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Tran%2C+Lucy+T%2E%22">Tran, Lucy T.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Zhou%2C+Shally%22">Zhou, Shally</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Puca%2C+Carla%22">Puca, Carla</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Hajarizadeh%2C+Behzad%22">Hajarizadeh, Behzad</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Larney%2C+Sarah%22">Larney, Sarah</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Santo%2C+Thomas%22">Santo, Thomas</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Higgins%2C+Julian+P%2E+T%2E%22">Higgins, Julian P. T.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Vickerman%2C+Peter%22">Vickerman, Peter</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Degenhardt%2C+Louisa%22">Degenhardt, Louisa</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Hickman%2C+Matthew%22">Hickman, Matthew</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22French%2C+Clare+E%2E%22">French, Clare E.</searchLink> (AUTHOR)
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22Addiction%22">Addiction</searchLink>. Jul2021, Vol. 116 Issue 7, p1664-1676. 13p. 3 Diagrams, 2 Charts, 2 Graphs.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Therapeutic+use+of+narcotics%22">Therapeutic use of narcotics</searchLink><br /><searchLink fieldCode="DE" term="%22Diagnosis+of+HIV+infections%22">Diagnosis of HIV infections</searchLink><br /><searchLink fieldCode="DE" term="%22Substance+abuse%22">Substance abuse</searchLink><br /><searchLink fieldCode="DE" term="%22Meta-analysis%22">Meta-analysis</searchLink><br /><searchLink fieldCode="DE" term="%22Analgesics%22">Analgesics</searchLink><br /><searchLink fieldCode="DE" term="%22Systematic+reviews%22">Systematic reviews</searchLink><br /><searchLink fieldCode="DE" term="%22Buprenorphine%22">Buprenorphine</searchLink><br /><searchLink fieldCode="DE" term="%22Medical+screening%22">Medical screening</searchLink><br /><searchLink fieldCode="DE" term="%22Methadone+hydrochloride%22">Methadone hydrochloride</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Background and aim: Globally, nearly one in five people who inject drugs (PWID) are living with HIV, and the rate of new HIV infections in PWID is increasing in some settings. Early diagnosis is crucial for effective HIV control. We reviewed the evidence on the association between opioid agonist therapy (OAT) and HIV testing uptake among PWID. Methods: We conducted a systematic review searching MEDLINE, Scopus, Web of Science, Cochrane Central Register of Controlled Trials and PsycINFO for studies published from January 2000 to March 2019. Reference lists and conference proceedings were hand‐searched. Observational and intervention studies were eligible for inclusion. Risk of bias was assessed using the Risk of Bias in Non‐Randomised Studies of Interventions (ROBINS‐I) tool. Meta‐analyses were conducted using random‐effects models. Results: Of 13 373 records identified, 11 studies from Australia, Europe, Malaysia and the United States were included. All studies had at least a serious risk of bias, largely due to confounding and selection bias, making it difficult to draw causal conclusions from the evidence. Ten studies provided data on the association between current OAT use and recent HIV testing. Six showed a positive association, while four provided little evidence of an association: pooled odds ratio (OR) = 1.71, 95% confidence interval (CI) = 1.28–2.27. Looking at having ever been on OAT and having ever been HIV tested, seven studies showed a positive association and three showed either weak or no evidence of an association: pooled OR = 3.82, 95% CI = 2.96–4.95. Conclusions: Opioid agonist therapy may increase uptake of HIV testing among people who inject drugs, providing further evidence that opioid agonist therapy improves the HIV treatment care cascade. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Addiction is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=150671468
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1111/add.15316
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 13
        StartPage: 1664
    Subjects:
      – SubjectFull: Therapeutic use of narcotics
        Type: general
      – SubjectFull: Diagnosis of HIV infections
        Type: general
      – SubjectFull: Substance abuse
        Type: general
      – SubjectFull: Meta-analysis
        Type: general
      – SubjectFull: Analgesics
        Type: general
      – SubjectFull: Systematic reviews
        Type: general
      – SubjectFull: Buprenorphine
        Type: general
      – SubjectFull: Medical screening
        Type: general
      – SubjectFull: Methadone hydrochloride
        Type: general
    Titles:
      – TitleFull: Association between opioid agonist therapy use and HIV testing uptake among people who have recently injected drugs: a systematic review and meta‐analysis.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Ferraro, Claire F.
      – PersonEntity:
          Name:
            NameFull: Stewart, Daniel E.
      – PersonEntity:
          Name:
            NameFull: Grebely, Jason
      – PersonEntity:
          Name:
            NameFull: Tran, Lucy T.
      – PersonEntity:
          Name:
            NameFull: Zhou, Shally
      – PersonEntity:
          Name:
            NameFull: Puca, Carla
      – PersonEntity:
          Name:
            NameFull: Hajarizadeh, Behzad
      – PersonEntity:
          Name:
            NameFull: Larney, Sarah
      – PersonEntity:
          Name:
            NameFull: Santo, Thomas
      – PersonEntity:
          Name:
            NameFull: Higgins, Julian P. T.
      – PersonEntity:
          Name:
            NameFull: Vickerman, Peter
      – PersonEntity:
          Name:
            NameFull: Degenhardt, Louisa
      – PersonEntity:
          Name:
            NameFull: Hickman, Matthew
      – PersonEntity:
          Name:
            NameFull: French, Clare E.
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 07
              Text: Jul2021
              Type: published
              Y: 2021
          Identifiers:
            – Type: issn-print
              Value: 09652140
          Numbering:
            – Type: volume
              Value: 116
            – Type: issue
              Value: 7
          Titles:
            – TitleFull: Addiction
              Type: main
ResultId 1