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Executive function in HIV-affected children and adolescents: a systematic review and meta-analyses.

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Title: Executive function in HIV-affected children and adolescents: a systematic review and meta-analyses.
Authors: Rowe, Kirsten, Buivydaite, Ruta, Heinsohn, Torben, Rahimzadeh, Mana, Wagner, Ryan G., Scerif, Gaia, Stein, Alan
Source: AIDS Care. Jul2021, Vol. 33 Issue 7, p833-857. 25p. 8 Diagrams, 6 Charts.
Subjects: Executive function, HIV-positive persons, CINAHL database, Online information services, Psychology information storage & retrieval systems, Meta-analysis, Medical databases, Information storage & retrieval systems, Systematic reviews, Neural development, Prenatal exposure delayed effects, MEDLINE, Vertical transmission (Communicable diseases), Children
Abstract: This review aimed to determine: whether EF is affected in children and adolescents (2–24-years-old) with perinatal HIV infection, perinatal HIV exposure without infection, and behaviourally acquired HIV. A systematic review (PROSPERO number: CRD42017067813) was conducted using 11 electronic databases (01.01.1981–09.07.2019) and 8 conference websites. Primary quantitative studies with EF scores on cognitive tasks and/or behavioural report measures were included. Meta-analyses were performed by EF subtype and subpopulations compared. 1789 records were found. Sixty-one studies were included in the narrative synthesis; 32 (N = 7884 participants) were included in meta-analyses. There was a distinct pattern of reduced EF in those with perinatal HIV infection on antiretroviral therapy compared to controls: pooled effect sizes were largest for verbal and visuospatial working memory, with smaller effects on planning, inhibitory control and set-shifting. Data were limited for other HIV-affected subpopulations. Perinatal HIV infection is associated with reduced EF with varying effect sizes for the different EF subtypes. [ABSTRACT FROM AUTHOR]
Copyright of AIDS Care is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: <searchLink fieldCode="JN" term="%22AIDS+Care%22">AIDS Care</searchLink>. Jul2021, Vol. 33 Issue 7, p833-857. 25p. 8 Diagrams, 6 Charts.
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  Data: This review aimed to determine: whether EF is affected in children and adolescents (2–24-years-old) with perinatal HIV infection, perinatal HIV exposure without infection, and behaviourally acquired HIV. A systematic review (PROSPERO number: CRD42017067813) was conducted using 11 electronic databases (01.01.1981–09.07.2019) and 8 conference websites. Primary quantitative studies with EF scores on cognitive tasks and/or behavioural report measures were included. Meta-analyses were performed by EF subtype and subpopulations compared. 1789 records were found. Sixty-one studies were included in the narrative synthesis; 32 (N = 7884 participants) were included in meta-analyses. There was a distinct pattern of reduced EF in those with perinatal HIV infection on antiretroviral therapy compared to controls: pooled effect sizes were largest for verbal and visuospatial working memory, with smaller effects on planning, inhibitory control and set-shifting. Data were limited for other HIV-affected subpopulations. Perinatal HIV infection is associated with reduced EF with varying effect sizes for the different EF subtypes. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of AIDS Care is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1080/09540121.2021.1873232
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      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 25
        StartPage: 833
    Subjects:
      – SubjectFull: Executive function
        Type: general
      – SubjectFull: HIV-positive persons
        Type: general
      – SubjectFull: CINAHL database
        Type: general
      – SubjectFull: Online information services
        Type: general
      – SubjectFull: Psychology information storage & retrieval systems
        Type: general
      – SubjectFull: Meta-analysis
        Type: general
      – SubjectFull: Medical databases
        Type: general
      – SubjectFull: Information storage & retrieval systems
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      – SubjectFull: Systematic reviews
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      – SubjectFull: Neural development
        Type: general
      – SubjectFull: Prenatal exposure delayed effects
        Type: general
      – SubjectFull: MEDLINE
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      – SubjectFull: Vertical transmission (Communicable diseases)
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      – SubjectFull: Children
        Type: general
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      – TitleFull: Executive function in HIV-affected children and adolescents: a systematic review and meta-analyses.
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            – D: 01
              M: 07
              Text: Jul2021
              Type: published
              Y: 2021
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