A Bayesian multilevel analysis of the longitudinal associations between relationship quality and suicidal ideation and attempts among youth with bipolar disorder.

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Title: A Bayesian multilevel analysis of the longitudinal associations between relationship quality and suicidal ideation and attempts among youth with bipolar disorder.
Authors: Sewall, Craig J.R., Girard, Jeffrey M., Merranko, John, Hafeman, Danella, Goldstein, Benjamin I., Strober, Michael, Hower, Heather, Weinstock, Lauren M., Yen, Shirley, Ryan, Neal D., Keller, Martin B., Liao, Fangzi, Diler, Rasim S., Kay Gill, Mary, Axelson, David, Birmaher, Boris, Goldstein, Tina R.
Source: Journal of Child Psychology & Psychiatry. Jul2021, Vol. 62 Issue 7, p905-915. 11p. 3 Charts, 2 Graphs.
Subjects: Affinity groups, Friendship, Psychology of parents, Suicidal ideation, Suicidal behavior, Interpersonal relations, Descriptive statistics, Parent-child relationships, Statistical models, Bipolar disorder, Probability theory, Longitudinal method
Abstract: Background: Youth with bipolar disorder (BD) are at high risk for suicidal thoughts and behaviors and frequently experience interpersonal impairment, which is a risk factor for suicide. Yet, no study to date has examined the longitudinal associations between relationship quality in family/peer domains and suicidal thoughts and behaviors among youth with BD. Thus, we investigated how between‐person differences – reflecting the average relationship quality across time – and within‐person changes, reflecting recent fluctuations in relationship quality, act as distal and/or proximal risk factors for suicidal ideation (SI) and suicide attempts. Methods: We used longitudinal data from the Course and Outcome of Bipolar Youth Study (N = 413). Relationship quality variables were decomposed into stable (i.e., average) and varying (i.e., recent) components and entered, along with major clinical covariates, into separate Bayesian multilevel models predicting SI and suicide attempt. We also examined how the relationship quality effects interacted with age and sex. Results: Poorer average relationship quality with parents (β = −.33, 95% Bayesian highest density interval (HDI) [−0.54, −0.11]) or friends (β = −.33, 95% HDI [−0.55, −0.11]) was longitudinally associated with increased risk of SI but not suicide attempt. Worsening recent relationship quality with parents (β = −.10, 95% HDI [−0.19, −0.03]) and, to a lesser extent, friends (β = −.06, 95% HDI [−0.15, 0.03]) was longitudinally associated with increased risk of SI, but only worsening recent relationship quality with parents was also associated with increased risk of suicide attempt (β = −.15, 95% HDI [−0.31, 0.01]). The effects of certain relationship quality variables were moderated by gender but not age. Conclusions: Among youth with BD, having poorer average relationship quality with peers and/or parents represents a distal risk factor for SI but not suicide attempts. Additionally, worsening recent relationship quality with parents may be a time‐sensitive indicator of increased risk for SI or suicide attempt. [ABSTRACT FROM AUTHOR]
Copyright of Journal of Child Psychology & Psychiatry is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: A Bayesian multilevel analysis of the longitudinal associations between relationship quality and suicidal ideation and attempts among youth with bipolar disorder.
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  Data: <searchLink fieldCode="AR" term="%22Sewall%2C+Craig+J%2ER%2E%22">Sewall, Craig J.R.</searchLink><br /><searchLink fieldCode="AR" term="%22Girard%2C+Jeffrey+M%2E%22">Girard, Jeffrey M.</searchLink><br /><searchLink fieldCode="AR" term="%22Merranko%2C+John%22">Merranko, John</searchLink><br /><searchLink fieldCode="AR" term="%22Hafeman%2C+Danella%22">Hafeman, Danella</searchLink><br /><searchLink fieldCode="AR" term="%22Goldstein%2C+Benjamin+I%2E%22">Goldstein, Benjamin I.</searchLink><br /><searchLink fieldCode="AR" term="%22Strober%2C+Michael%22">Strober, Michael</searchLink><br /><searchLink fieldCode="AR" term="%22Hower%2C+Heather%22">Hower, Heather</searchLink><br /><searchLink fieldCode="AR" term="%22Weinstock%2C+Lauren+M%2E%22">Weinstock, Lauren M.</searchLink><br /><searchLink fieldCode="AR" term="%22Yen%2C+Shirley%22">Yen, Shirley</searchLink><br /><searchLink fieldCode="AR" term="%22Ryan%2C+Neal+D%2E%22">Ryan, Neal D.</searchLink><br /><searchLink fieldCode="AR" term="%22Keller%2C+Martin+B%2E%22">Keller, Martin B.</searchLink><br /><searchLink fieldCode="AR" term="%22Liao%2C+Fangzi%22">Liao, Fangzi</searchLink><br /><searchLink fieldCode="AR" term="%22Diler%2C+Rasim+S%2E%22">Diler, Rasim S.</searchLink><br /><searchLink fieldCode="AR" term="%22Kay+Gill%2C+Mary%22">Kay Gill, Mary</searchLink><br /><searchLink fieldCode="AR" term="%22Axelson%2C+David%22">Axelson, David</searchLink><br /><searchLink fieldCode="AR" term="%22Birmaher%2C+Boris%22">Birmaher, Boris</searchLink><br /><searchLink fieldCode="AR" term="%22Goldstein%2C+Tina+R%2E%22">Goldstein, Tina R.</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22Journal+of+Child+Psychology+%26+Psychiatry%22">Journal of Child Psychology & Psychiatry</searchLink>. Jul2021, Vol. 62 Issue 7, p905-915. 11p. 3 Charts, 2 Graphs.
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  Data: <searchLink fieldCode="DE" term="%22Affinity+groups%22">Affinity groups</searchLink><br /><searchLink fieldCode="DE" term="%22Friendship%22">Friendship</searchLink><br /><searchLink fieldCode="DE" term="%22Psychology+of+parents%22">Psychology of parents</searchLink><br /><searchLink fieldCode="DE" term="%22Suicidal+ideation%22">Suicidal ideation</searchLink><br /><searchLink fieldCode="DE" term="%22Suicidal+behavior%22">Suicidal behavior</searchLink><br /><searchLink fieldCode="DE" term="%22Interpersonal+relations%22">Interpersonal relations</searchLink><br /><searchLink fieldCode="DE" term="%22Descriptive+statistics%22">Descriptive statistics</searchLink><br /><searchLink fieldCode="DE" term="%22Parent-child+relationships%22">Parent-child relationships</searchLink><br /><searchLink fieldCode="DE" term="%22Statistical+models%22">Statistical models</searchLink><br /><searchLink fieldCode="DE" term="%22Bipolar+disorder%22">Bipolar disorder</searchLink><br /><searchLink fieldCode="DE" term="%22Probability+theory%22">Probability theory</searchLink><br /><searchLink fieldCode="DE" term="%22Longitudinal+method%22">Longitudinal method</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Background: Youth with bipolar disorder (BD) are at high risk for suicidal thoughts and behaviors and frequently experience interpersonal impairment, which is a risk factor for suicide. Yet, no study to date has examined the longitudinal associations between relationship quality in family/peer domains and suicidal thoughts and behaviors among youth with BD. Thus, we investigated how between‐person differences – reflecting the average relationship quality across time – and within‐person changes, reflecting recent fluctuations in relationship quality, act as distal and/or proximal risk factors for suicidal ideation (SI) and suicide attempts. Methods: We used longitudinal data from the Course and Outcome of Bipolar Youth Study (N = 413). Relationship quality variables were decomposed into stable (i.e., average) and varying (i.e., recent) components and entered, along with major clinical covariates, into separate Bayesian multilevel models predicting SI and suicide attempt. We also examined how the relationship quality effects interacted with age and sex. Results: Poorer average relationship quality with parents (β = −.33, 95% Bayesian highest density interval (HDI) [−0.54, −0.11]) or friends (β = −.33, 95% HDI [−0.55, −0.11]) was longitudinally associated with increased risk of SI but not suicide attempt. Worsening recent relationship quality with parents (β = −.10, 95% HDI [−0.19, −0.03]) and, to a lesser extent, friends (β = −.06, 95% HDI [−0.15, 0.03]) was longitudinally associated with increased risk of SI, but only worsening recent relationship quality with parents was also associated with increased risk of suicide attempt (β = −.15, 95% HDI [−0.31, 0.01]). The effects of certain relationship quality variables were moderated by gender but not age. Conclusions: Among youth with BD, having poorer average relationship quality with peers and/or parents represents a distal risk factor for SI but not suicide attempts. Additionally, worsening recent relationship quality with parents may be a time‐sensitive indicator of increased risk for SI or suicide attempt. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
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  Data: <i>Copyright of Journal of Child Psychology & Psychiatry is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Value: 10.1111/jcpp.13343
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        Text: English
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      – SubjectFull: Friendship
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      – SubjectFull: Psychology of parents
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      – SubjectFull: Suicidal ideation
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      – SubjectFull: Interpersonal relations
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      – SubjectFull: Descriptive statistics
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      – SubjectFull: Parent-child relationships
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      – SubjectFull: Bipolar disorder
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      – SubjectFull: Probability theory
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      – SubjectFull: Longitudinal method
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