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Pilot trial of a mouthpiece as treatment for signs and symptoms of Parkinson disease.

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Title: Pilot trial of a mouthpiece as treatment for signs and symptoms of Parkinson disease.
Authors: May, David Scott (AUTHOR), Rawson, Kerri Sharp (AUTHOR), Moeller, Donald Richard (AUTHOR), Tueth, Lauren Elizabeth (AUTHOR), Earhart, Gammon M. (AUTHOR)
Source: Somatosensory & Motor Research. Sep2021, Vol. 38 Issue 3, p223-229. 7p.
Subjects: Parkinson's disease, Symptoms, Quality of life, Wilcoxon signed-rank test, Multiple comparisons (Statistics)
Geographic Terms: Delhi (India)
Abstract: Several case studies and anecdotal reports have shown assorted motor and quality of life benefits from use of a dental mouthpiece among people with Parkinson disease (PD). A larger exploratory study is necessary to assess potential efficacy and feasibility of this treatment strategy. If shown to be effective and feasible in a larger sample of people with PD, mechanistic studies may be warranted to examine a potential relationship between orofacial sensory input and motor function in people with PD. This study was registered on clinicaltrials.gov (NCT: 04082663). Twenty people with PD, Hoehn and Yahr stages I-III, participated in this study. Each participant completed various baseline motor and quality of life assessments before being fitted with a custom mouthpiece. Motor assessments were completed a second time after 25 min of mouthpiece wear. Participants were asked to wear the mouthpiece for 1 month before completing follow-up quality of life assessments and providing feedback about the mouthpiece. Wilcoxon signed-rank tests were used to compare results across conditions. Gait velocity and cadence showed significant (p <.05) improvement while wearing the mouthpiece. However, these changes were not significant after correcting for multiple comparisons. Thirteen participants indicated they would be unlikely to continue wearing the mouthpiece. These results do not provide adequate evidence to pursue further this type of mouthpiece as a treatment strategy for motor signs and symptoms or quality of life in people with PD. [ABSTRACT FROM AUTHOR]
Copyright of Somatosensory & Motor Research is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Pilot trial of a mouthpiece as treatment for signs and symptoms of Parkinson disease.
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  Data: &lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22May%2C+David+Scott%22&quot;&gt;May, David Scott&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Rawson%2C+Kerri+Sharp%22&quot;&gt;Rawson, Kerri Sharp&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Moeller%2C+Donald+Richard%22&quot;&gt;Moeller, Donald Richard&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Tueth%2C+Lauren+Elizabeth%22&quot;&gt;Tueth, Lauren Elizabeth&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Earhart%2C+Gammon+M%2E%22&quot;&gt;Earhart, Gammon M.&lt;/searchLink&gt; (AUTHOR)
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  Data: &lt;searchLink fieldCode=&quot;JN&quot; term=&quot;%22Somatosensory+%26+Motor+Research%22&quot;&gt;Somatosensory &amp; Motor Research&lt;/searchLink&gt;. Sep2021, Vol. 38 Issue 3, p223-229. 7p.
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  Data: &lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Parkinson&#39;s+disease%22&quot;&gt;Parkinson&#39;s disease&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Symptoms%22&quot;&gt;Symptoms&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Quality+of+life%22&quot;&gt;Quality of life&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Wilcoxon+signed-rank+test%22&quot;&gt;Wilcoxon signed-rank test&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Multiple+comparisons+%28Statistics%29%22&quot;&gt;Multiple comparisons (Statistics)&lt;/searchLink&gt;
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  Data: &lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Delhi+%28India%29%22&quot;&gt;Delhi (India)&lt;/searchLink&gt;
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Several case studies and anecdotal reports have shown assorted motor and quality of life benefits from use of a dental mouthpiece among people with Parkinson disease (PD). A larger exploratory study is necessary to assess potential efficacy and feasibility of this treatment strategy. If shown to be effective and feasible in a larger sample of people with PD, mechanistic studies may be warranted to examine a potential relationship between orofacial sensory input and motor function in people with PD. This study was registered on clinicaltrials.gov (NCT: 04082663). Twenty people with PD, Hoehn and Yahr stages I-III, participated in this study. Each participant completed various baseline motor and quality of life assessments before being fitted with a custom mouthpiece. Motor assessments were completed a second time after 25 min of mouthpiece wear. Participants were asked to wear the mouthpiece for 1 month before completing follow-up quality of life assessments and providing feedback about the mouthpiece. Wilcoxon signed-rank tests were used to compare results across conditions. Gait velocity and cadence showed significant (p &lt;.05) improvement while wearing the mouthpiece. However, these changes were not significant after correcting for multiple comparisons. Thirteen participants indicated they would be unlikely to continue wearing the mouthpiece. These results do not provide adequate evidence to pursue further this type of mouthpiece as a treatment strategy for motor signs and symptoms or quality of life in people with PD. [ABSTRACT FROM AUTHOR]
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  Data: &lt;i&gt;Copyright of Somatosensory &amp; Motor Research is the property of Taylor &amp; Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=151912402
RecordInfo BibRecord:
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    Identifiers:
      – Type: doi
        Value: 10.1080/08990220.2021.1953462
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 7
        StartPage: 223
    Subjects:
      – SubjectFull: Parkinson's disease
        Type: general
      – SubjectFull: Symptoms
        Type: general
      – SubjectFull: Quality of life
        Type: general
      – SubjectFull: Wilcoxon signed-rank test
        Type: general
      – SubjectFull: Multiple comparisons (Statistics)
        Type: general
      – SubjectFull: Delhi (India)
        Type: general
    Titles:
      – TitleFull: Pilot trial of a mouthpiece as treatment for signs and symptoms of Parkinson disease.
        Type: main
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      – PersonEntity:
          Name:
            NameFull: May, David Scott
      – PersonEntity:
          Name:
            NameFull: Rawson, Kerri Sharp
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            NameFull: Moeller, Donald Richard
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            NameFull: Tueth, Lauren Elizabeth
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            NameFull: Earhart, Gammon M.
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            – D: 01
              M: 09
              Text: Sep2021
              Type: published
              Y: 2021
          Identifiers:
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              Value: 08990220
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              Value: 38
            – Type: issue
              Value: 3
          Titles:
            – TitleFull: Somatosensory & Motor Research
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