How to manage N waste in the intestine?
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| Title: | How to manage N waste in the intestine? |
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| Source: | Acta Physiologica. Sep2021, Vol. 233 Issue 1, p1-4. 4p. 1 Diagram. |
| Subjects: | Glutamine synthetase, TRPV cation channels, Intestines, Cell membranes, Gastrointestinal mucosa, Molecular structure |
| Abstract: | The known poor selectivity of these cation channels including their permeability for NH SB 4 sb SP + sp (shown already for the bovine orthologue (bTRPV3)2), led the authors to hypothesize that these channels might be involved in the intestinal absorption of NH SB 4 sb SP + sp . GLO:2QJP/01sep21:apha13711-fig-0001.jpg PHOTO (COLOR): 1 Ammonia (NH3), which is present in the lumen of the large intestine mainly in the form of ammonium ions (NH4+), is absorbed in the ionic form by the intestinal epithelium via TRPV3 and/or TRPV4 channels in the apical membrane. Thus, it might be speculated that a (modest) supply of the liver with NH SB 3 sb by absorption of NH SB 4 sb SP + sp across the large intestinal epithelium could have been helpful evolutionary to contribute to the support of the mammal with nitrogen for NH SB 3 sb fixation. [Extracted from the article] |
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| Database: | Psychology and Behavioral Sciences Collection |
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| Abstract: | The known poor selectivity of these cation channels including their permeability for NH SB 4 sb SP + sp (shown already for the bovine orthologue (bTRPV3)2), led the authors to hypothesize that these channels might be involved in the intestinal absorption of NH SB 4 sb SP + sp . GLO:2QJP/01sep21:apha13711-fig-0001.jpg PHOTO (COLOR): 1 Ammonia (NH3), which is present in the lumen of the large intestine mainly in the form of ammonium ions (NH4+), is absorbed in the ionic form by the intestinal epithelium via TRPV3 and/or TRPV4 channels in the apical membrane. Thus, it might be speculated that a (modest) supply of the liver with NH SB 3 sb by absorption of NH SB 4 sb SP + sp across the large intestinal epithelium could have been helpful evolutionary to contribute to the support of the mammal with nitrogen for NH SB 3 sb fixation. [Extracted from the article] |
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| ISSN: | 17481708 |
| DOI: | 10.1111/apha.13711 |
