An integrated parenting intervention for maternal depression and child development in a low‐resource setting: Cluster randomized controlled trial.

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Title: An integrated parenting intervention for maternal depression and child development in a low‐resource setting: Cluster randomized controlled trial.
Authors: Husain, Nusrat (AUTHOR), Kiran, Tayyeba (AUTHOR), Fatima, Batool (AUTHOR), Chaudhry, Imran B. (AUTHOR), Husain, Mina (AUTHOR), Shah, Sadia (AUTHOR), Bassett, Paul (AUTHOR), Cohen, Nancy (AUTHOR), Jafri, Farhat (AUTHOR), Naeem, Shehla (AUTHOR), Zadeh, Zainab (AUTHOR), Roberts, Chris (AUTHOR), Rahman, Atif (AUTHOR), Naeem, Farooq (AUTHOR), Husain, Muhammad Ishrat (AUTHOR), Chaudhry, Nasim (AUTHOR)
Source: Depression & Anxiety (1091-4269). Sep2021, Vol. 38 Issue 9, p925-939. 15p. 2 Diagrams, 8 Charts.
Subjects: Cluster randomized controlled trials, Child development, Parents, Edinburgh Postnatal Depression Scale, Quality of life
Geographic Terms: Karachi (Pakistan), Pakistan
Abstract: Background: Rates of depression among Pakistani mothers are high, leading to poor developmental outcomes in their children. This study tested the effectiveness of a manualized integrated parenting program; Learning through Play Plus (LTP+) for maternal depression in Karachi, Pakistan. Methods: A cluster randomized control trial conducted from January 2014 to December 2015 across 120 villages in Karachi. A total of 774 depressed mothers aged 18–44 years with children aged 0–30 months old, were included. Villages were randomized to receive LTP+ added to treatment as usual (TAU) or TAU alone. Primary outcomes were severity of maternal depression at 3 and 6 months measured by the Edinburgh Postnatal Depression Scale and child socio‐emotional development at 6 months measured by the Ages and Stages Questionnaire (ASQ). Secondary outcomes included maternal anxiety, quality of life, social support, parenting competence, and knowledge about child development. Results: Mothers in the LTP+ group reported significantly lower depression scores compared to those in the TAU group (6.6 vs. 13.8, effect size [ES]: −7.2; 95% confidence interval [CI]: −8.2, −6.1) at 3 and 6 months (7.2 vs. 12.00; ES: −4.6; 95% CI: −5.9, −3.4). Child socio‐emotional development at 6 months was significantly better in the LTP+ group on all domains of the ASQ. There were also statistically significant improvements on all secondary outcomes at 3‐ and 6‐month follow‐up. Conclusion: In low‐resource settings like Pakistan, low‐cost integrated parenting interventions delivered by lay health workers can provide effective treatment for depressed mothers, leading to improvements in child development. [ABSTRACT FROM AUTHOR]
Copyright of Depression & Anxiety (1091-4269) is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: An integrated parenting intervention for maternal depression and child development in a low‐resource setting: Cluster randomized controlled trial.
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  Data: <searchLink fieldCode="AR" term="%22Husain%2C+Nusrat%22">Husain, Nusrat</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kiran%2C+Tayyeba%22">Kiran, Tayyeba</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Fatima%2C+Batool%22">Fatima, Batool</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Chaudhry%2C+Imran+B%2E%22">Chaudhry, Imran B.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Husain%2C+Mina%22">Husain, Mina</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Shah%2C+Sadia%22">Shah, Sadia</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Bassett%2C+Paul%22">Bassett, Paul</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Cohen%2C+Nancy%22">Cohen, Nancy</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Jafri%2C+Farhat%22">Jafri, Farhat</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Naeem%2C+Shehla%22">Naeem, Shehla</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Zadeh%2C+Zainab%22">Zadeh, Zainab</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Roberts%2C+Chris%22">Roberts, Chris</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Rahman%2C+Atif%22">Rahman, Atif</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Naeem%2C+Farooq%22">Naeem, Farooq</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Husain%2C+Muhammad+Ishrat%22">Husain, Muhammad Ishrat</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Chaudhry%2C+Nasim%22">Chaudhry, Nasim</searchLink> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22Depression+%26+Anxiety+%281091-4269%29%22">Depression & Anxiety (1091-4269)</searchLink>. Sep2021, Vol. 38 Issue 9, p925-939. 15p. 2 Diagrams, 8 Charts.
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  Data: <searchLink fieldCode="DE" term="%22Cluster+randomized+controlled+trials%22">Cluster randomized controlled trials</searchLink><br /><searchLink fieldCode="DE" term="%22Child+development%22">Child development</searchLink><br /><searchLink fieldCode="DE" term="%22Parents%22">Parents</searchLink><br /><searchLink fieldCode="DE" term="%22Edinburgh+Postnatal+Depression+Scale%22">Edinburgh Postnatal Depression Scale</searchLink><br /><searchLink fieldCode="DE" term="%22Quality+of+life%22">Quality of life</searchLink>
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  Data: <searchLink fieldCode="DE" term="%22Karachi+%28Pakistan%29%22">Karachi (Pakistan)</searchLink><br /><searchLink fieldCode="DE" term="%22Pakistan%22">Pakistan</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Background: Rates of depression among Pakistani mothers are high, leading to poor developmental outcomes in their children. This study tested the effectiveness of a manualized integrated parenting program; Learning through Play Plus (LTP+) for maternal depression in Karachi, Pakistan. Methods: A cluster randomized control trial conducted from January 2014 to December 2015 across 120 villages in Karachi. A total of 774 depressed mothers aged 18–44 years with children aged 0–30 months old, were included. Villages were randomized to receive LTP+ added to treatment as usual (TAU) or TAU alone. Primary outcomes were severity of maternal depression at 3 and 6 months measured by the Edinburgh Postnatal Depression Scale and child socio‐emotional development at 6 months measured by the Ages and Stages Questionnaire (ASQ). Secondary outcomes included maternal anxiety, quality of life, social support, parenting competence, and knowledge about child development. Results: Mothers in the LTP+ group reported significantly lower depression scores compared to those in the TAU group (6.6 vs. 13.8, effect size [ES]: −7.2; 95% confidence interval [CI]: −8.2, −6.1) at 3 and 6 months (7.2 vs. 12.00; ES: −4.6; 95% CI: −5.9, −3.4). Child socio‐emotional development at 6 months was significantly better in the LTP+ group on all domains of the ASQ. There were also statistically significant improvements on all secondary outcomes at 3‐ and 6‐month follow‐up. Conclusion: In low‐resource settings like Pakistan, low‐cost integrated parenting interventions delivered by lay health workers can provide effective treatment for depressed mothers, leading to improvements in child development. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Depression & Anxiety (1091-4269) is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1002/da.23169
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      – Code: eng
        Text: English
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        PageCount: 15
        StartPage: 925
    Subjects:
      – SubjectFull: Cluster randomized controlled trials
        Type: general
      – SubjectFull: Child development
        Type: general
      – SubjectFull: Parents
        Type: general
      – SubjectFull: Edinburgh Postnatal Depression Scale
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      – SubjectFull: Karachi (Pakistan)
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      – SubjectFull: Pakistan
        Type: general
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      – TitleFull: An integrated parenting intervention for maternal depression and child development in a low‐resource setting: Cluster randomized controlled trial.
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              Text: Sep2021
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