Gastrointestinal Symptoms in 2- to 5-Year-Old Children in the Study to Explore Early Development.

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Title: Gastrointestinal Symptoms in 2- to 5-Year-Old Children in the Study to Explore Early Development.
Authors: Reynolds, Ann M., Soke, Gnakub N., Sabourin, Katherine R., Croen, Lisa A., Daniels, Julie L., Fallin, M. Daniele, Kral, Tanja V. E., Lee, Li- Ching, Newschaffer, Craig J., Pinto-Martin, Jennifer A., Schieve, Laura A., Sims, Amy, Wiggins, Lisa, Levy, Susan E.
Source: Journal of Autism & Developmental Disorders. Nov2021, Vol. 51 Issue 11, p3806-3817. 12p. 2 Diagrams, 7 Charts.
Subjects: Research, Child development, Gastrointestinal diseases, Children with disabilities, Medical cooperation, Neural development, Behavior disorders in children, Sleep disorders in children, Severity of illness index, Autism in children, Disease prevalence, Child development deviations, Phenotypes, Parents, Symptoms, Children
Abstract: Gastrointestinal symptoms (GIS) are commonly reported in children with autism spectrum disorder (ASD). This multi-site study evaluated the prevalence of GIS in preschool-aged children with ASD/(n = 672), with other developmental delays (DD)/(n = 938), and children in the general population (POP)/(n = 851). After adjusting for covariates, children in the ASD group were over 3 times more likely to have parent-reported GIS than the POP group, and almost 2 times more likely than the DD group. Children with GIS from all groups had more behavioral and sleep problems. Within the ASD group, children with developmental regression had more GIS than those without; however, there were no differences in autism severity scores between children with and without GIS. These findings have implications for clinical management. [ABSTRACT FROM AUTHOR]
Copyright of Journal of Autism & Developmental Disorders is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Gastrointestinal Symptoms in 2- to 5-Year-Old Children in the Study to Explore Early Development.
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  Data: <searchLink fieldCode="AR" term="%22Reynolds%2C+Ann+M%2E%22">Reynolds, Ann M.</searchLink><br /><searchLink fieldCode="AR" term="%22Soke%2C+Gnakub+N%2E%22">Soke, Gnakub N.</searchLink><br /><searchLink fieldCode="AR" term="%22Sabourin%2C+Katherine+R%2E%22">Sabourin, Katherine R.</searchLink><br /><searchLink fieldCode="AR" term="%22Croen%2C+Lisa+A%2E%22">Croen, Lisa A.</searchLink><br /><searchLink fieldCode="AR" term="%22Daniels%2C+Julie+L%2E%22">Daniels, Julie L.</searchLink><br /><searchLink fieldCode="AR" term="%22Fallin%2C+M%2E+Daniele%22">Fallin, M. Daniele</searchLink><br /><searchLink fieldCode="AR" term="%22Kral%2C+Tanja+V%2E+E%2E%22">Kral, Tanja V. E.</searchLink><br /><searchLink fieldCode="AR" term="%22Lee%2C+Li-+Ching%22">Lee, Li- Ching</searchLink><br /><searchLink fieldCode="AR" term="%22Newschaffer%2C+Craig+J%2E%22">Newschaffer, Craig J.</searchLink><br /><searchLink fieldCode="AR" term="%22Pinto-Martin%2C+Jennifer+A%2E%22">Pinto-Martin, Jennifer A.</searchLink><br /><searchLink fieldCode="AR" term="%22Schieve%2C+Laura+A%2E%22">Schieve, Laura A.</searchLink><br /><searchLink fieldCode="AR" term="%22Sims%2C+Amy%22">Sims, Amy</searchLink><br /><searchLink fieldCode="AR" term="%22Wiggins%2C+Lisa%22">Wiggins, Lisa</searchLink><br /><searchLink fieldCode="AR" term="%22Levy%2C+Susan+E%2E%22">Levy, Susan E.</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22Journal+of+Autism+%26+Developmental+Disorders%22">Journal of Autism & Developmental Disorders</searchLink>. Nov2021, Vol. 51 Issue 11, p3806-3817. 12p. 2 Diagrams, 7 Charts.
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  Data: <searchLink fieldCode="DE" term="%22Research%22">Research</searchLink><br /><searchLink fieldCode="DE" term="%22Child+development%22">Child development</searchLink><br /><searchLink fieldCode="DE" term="%22Gastrointestinal+diseases%22">Gastrointestinal diseases</searchLink><br /><searchLink fieldCode="DE" term="%22Children+with+disabilities%22">Children with disabilities</searchLink><br /><searchLink fieldCode="DE" term="%22Medical+cooperation%22">Medical cooperation</searchLink><br /><searchLink fieldCode="DE" term="%22Neural+development%22">Neural development</searchLink><br /><searchLink fieldCode="DE" term="%22Behavior+disorders+in+children%22">Behavior disorders in children</searchLink><br /><searchLink fieldCode="DE" term="%22Sleep+disorders+in+children%22">Sleep disorders in children</searchLink><br /><searchLink fieldCode="DE" term="%22Severity+of+illness+index%22">Severity of illness index</searchLink><br /><searchLink fieldCode="DE" term="%22Autism+in+children%22">Autism in children</searchLink><br /><searchLink fieldCode="DE" term="%22Disease+prevalence%22">Disease prevalence</searchLink><br /><searchLink fieldCode="DE" term="%22Child+development+deviations%22">Child development deviations</searchLink><br /><searchLink fieldCode="DE" term="%22Phenotypes%22">Phenotypes</searchLink><br /><searchLink fieldCode="DE" term="%22Parents%22">Parents</searchLink><br /><searchLink fieldCode="DE" term="%22Symptoms%22">Symptoms</searchLink><br /><searchLink fieldCode="DE" term="%22Children%22">Children</searchLink>
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  Data: Gastrointestinal symptoms (GIS) are commonly reported in children with autism spectrum disorder (ASD). This multi-site study evaluated the prevalence of GIS in preschool-aged children with ASD/(n = 672), with other developmental delays (DD)/(n = 938), and children in the general population (POP)/(n = 851). After adjusting for covariates, children in the ASD group were over 3 times more likely to have parent-reported GIS than the POP group, and almost 2 times more likely than the DD group. Children with GIS from all groups had more behavioral and sleep problems. Within the ASD group, children with developmental regression had more GIS than those without; however, there were no differences in autism severity scores between children with and without GIS. These findings have implications for clinical management. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Journal of Autism & Developmental Disorders is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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      – Type: doi
        Value: 10.1007/s10803-020-04786-9
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        Text: English
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        PageCount: 12
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        Type: general
      – SubjectFull: Child development
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      – SubjectFull: Gastrointestinal diseases
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      – SubjectFull: Medical cooperation
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      – SubjectFull: Neural development
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      – SubjectFull: Behavior disorders in children
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      – SubjectFull: Symptoms
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