Kikuchi's Disease in Asian Children.
Saved in:
| Title: | Kikuchi's Disease in Asian Children. |
|---|---|
| Authors: | Hsin-Ching Lin, Chih-Ying Su, Shun-Chen Huang |
| Source: | Pediatrics. Jan2005, Vol. 115 Issue 1, pe92-e96. 5p. 1 Chart. |
| Subjects: | Lymphadenitis, Lymphatic diseases, Lymph nodes, Juvenile diseases, Pediatrics |
| Abstract: | Objective. Kikuchi's disease (KD), or histiocytic necrotizing lymphadenitis, is a unique form of self-limiting lymphadenitis and typically affects the head and neck regions. It usually occurs in young adults and has a female predilection. The aim of this study was to review the authors' institutional experience with KD in children over a 16-year period. Methods. Between January 1986 and May 2002, a total of 23 patients who were younger than 16 years underwent cervical lymph node biopsies and received a diagnosis of KD. Clinical features, laboratory values, pathologic parameters, specific characteristics of our pediatric patients, and long-term follow-up results are discussed. The follow-up period averaged 8 years. Results. There were 8 girls and 15 boys with a mean age of 12.8. All 23 patients had affected cervical lymph nodes located in the posterior cervical triangle, and 2 cases additionally had affected nodes in the anterior triangle. Cervical lymph nodes were affected unilaterally in 82.6% (19) and bilaterally in 17.4% (4) of these patients. The dimensions of the affected lymph nodes were commonly in the range of 0.5 to 3 cm (52.2%; 12 of 23) and 3 to 6 cm (39.1%; 9 of 23). In 2 (8.7%) patients, the size of the enlarged lymph nodes reached >6 cm. Leukopenia was observed in 5 (21.7%) patients, and fever was observed in 7 (30.4%) patients. One child with KD developed systemic lupus erythematosus 5 years later. The cervical lymphadenopathy usually resolved itself without any medical treatment within 6 months after definite diagnosis was made. Neither recurrence nor persisting KD has since been noted. Conclusion. KD, although rare, should be part of the differential diagnosis for posterior cervical lymphade-nopathy in children, especially in patients of Asian descent. In our pediatric series, KD demonstrated a male predominance, which is in contrast to previously reported adult series demonstrating a female predominance. The children with KD require a... [ABSTRACT FROM AUTHOR] |
| Copyright of Pediatrics is the property of American Academy of Pediatrics and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
| FullText | Text: Availability: 0 |
|---|---|
| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 15390225 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
| IllustrationInfo | |
| Items | – Name: Title Label: Title Group: Ti Data: Kikuchi's Disease in Asian Children. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Hsin-Ching+Lin%22">Hsin-Ching Lin</searchLink><br /><searchLink fieldCode="AR" term="%22Chih-Ying+Su%22">Chih-Ying Su</searchLink><br /><searchLink fieldCode="AR" term="%22Shun-Chen+Huang%22">Shun-Chen Huang</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Pediatrics%22">Pediatrics</searchLink>. Jan2005, Vol. 115 Issue 1, pe92-e96. 5p. 1 Chart. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Lymphadenitis%22">Lymphadenitis</searchLink><br /><searchLink fieldCode="DE" term="%22Lymphatic+diseases%22">Lymphatic diseases</searchLink><br /><searchLink fieldCode="DE" term="%22Lymph+nodes%22">Lymph nodes</searchLink><br /><searchLink fieldCode="DE" term="%22Juvenile+diseases%22">Juvenile diseases</searchLink><br /><searchLink fieldCode="DE" term="%22Pediatrics%22">Pediatrics</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Objective. Kikuchi's disease (KD), or histiocytic necrotizing lymphadenitis, is a unique form of self-limiting lymphadenitis and typically affects the head and neck regions. It usually occurs in young adults and has a female predilection. The aim of this study was to review the authors' institutional experience with KD in children over a 16-year period. Methods. Between January 1986 and May 2002, a total of 23 patients who were younger than 16 years underwent cervical lymph node biopsies and received a diagnosis of KD. Clinical features, laboratory values, pathologic parameters, specific characteristics of our pediatric patients, and long-term follow-up results are discussed. The follow-up period averaged 8 years. Results. There were 8 girls and 15 boys with a mean age of 12.8. All 23 patients had affected cervical lymph nodes located in the posterior cervical triangle, and 2 cases additionally had affected nodes in the anterior triangle. Cervical lymph nodes were affected unilaterally in 82.6% (19) and bilaterally in 17.4% (4) of these patients. The dimensions of the affected lymph nodes were commonly in the range of 0.5 to 3 cm (52.2%; 12 of 23) and 3 to 6 cm (39.1%; 9 of 23). In 2 (8.7%) patients, the size of the enlarged lymph nodes reached >6 cm. Leukopenia was observed in 5 (21.7%) patients, and fever was observed in 7 (30.4%) patients. One child with KD developed systemic lupus erythematosus 5 years later. The cervical lymphadenopathy usually resolved itself without any medical treatment within 6 months after definite diagnosis was made. Neither recurrence nor persisting KD has since been noted. Conclusion. KD, although rare, should be part of the differential diagnosis for posterior cervical lymphade-nopathy in children, especially in patients of Asian descent. In our pediatric series, KD demonstrated a male predominance, which is in contrast to previously reported adult series demonstrating a female predominance. The children with KD require a... [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Pediatrics is the property of American Academy of Pediatrics and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=15390225 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1542/peds.2004-0924 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 5 StartPage: e92 Subjects: – SubjectFull: Lymphadenitis Type: general – SubjectFull: Lymphatic diseases Type: general – SubjectFull: Lymph nodes Type: general – SubjectFull: Juvenile diseases Type: general – SubjectFull: Pediatrics Type: general Titles: – TitleFull: Kikuchi's Disease in Asian Children. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Hsin-Ching Lin – PersonEntity: Name: NameFull: Chih-Ying Su – PersonEntity: Name: NameFull: Shun-Chen Huang IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 01 Text: Jan2005 Type: published Y: 2005 Identifiers: – Type: issn-print Value: 00314005 Numbering: – Type: volume Value: 115 – Type: issue Value: 1 Titles: – TitleFull: Pediatrics Type: main |
| ResultId | 1 |
