Pediatric Medication Noninitiation in Spain.

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Title: Pediatric Medication Noninitiation in Spain.
Authors: Carbonell-Duacastella, Cristina, Rubio-Valera, Maria, Marqués-Ercilla, Sílvia, Penarrubia-María, Maria Teresa, Gil-Girbau, Montserrat, Garcia-Cardenas, Victoria, Pasarín, Maria Isabel, Parody-Rúa, Elizabeth, Aznar-Lou, Ignacio
Source: Pediatrics. Jan2022, Vol. 149 Issue 1, p48-58. 11p.
Subjects: Scientific observation, Health services accessibility, Multivariate analysis, Medical care costs, Drug administration, Health behavior, Drugs, At-risk people, Patient compliance, Logistic regression analysis, Odds ratio
Geographic Terms: Spain
Abstract: OBJECTIVES: To estimate medication noninitiation prevalence in the pediatric population and identify the explanatory factors underlying this behavior. METHODS: Observational study of patients (<18 years old) receiving at least 1 new prescription (28 pharmaceutical subgroups; July 2017 to June 2018) in Catalonia, Spain. A prescription was considered new when there was no prescription for the same pharmaceutical subgroup in the previous 6 months. Noninitiation occurred when a prescription was not filled within 1 month or 6 months (sensitivity analysis). Prevalence was estimated as the proportion of total prescriptions not initiated. To identify explanatory factors, a multivariable multilevel logistic regression model was used, and adjusted odds ratios were reported. RESULTS: Overall, 1 539 003 new prescriptions were issued to 715 895 children. The overall prevalence of 1-month noninitiation was 9.0% (ranging from 2.6% [oral antibiotics] to 21.5% [proton pump inhibitors]), and the prevalence of 6-month noninitiation was 8.5%. Noninitiation was higher in the youngest and oldest population groups, in children from families with a 0% copayment rate (vulnerable populations) and those with conditions from external causes. Out-of-pocket costs of drugs increased the odds of noninitiation. The odds of noninitiation were lower when the prescription was issued by a pediatrician (compared with a primary or secondary care clinician). CONCLUSIONS: The prevalence of noninitiation of medical treatments in pediatrics is high and varies according to patients' ages and medical groups. Results suggest that there are inequities in access to pharmacologic treatments in this population that must be taken into account by health care planners and providers. [ABSTRACT FROM AUTHOR]
Copyright of Pediatrics is the property of American Academy of Pediatrics and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: OBJECTIVES: To estimate medication noninitiation prevalence in the pediatric population and identify the explanatory factors underlying this behavior. METHODS: Observational study of patients (&lt;18 years old) receiving at least 1 new prescription (28 pharmaceutical subgroups; July 2017 to June 2018) in Catalonia, Spain. A prescription was considered new when there was no prescription for the same pharmaceutical subgroup in the previous 6 months. Noninitiation occurred when a prescription was not filled within 1 month or 6 months (sensitivity analysis). Prevalence was estimated as the proportion of total prescriptions not initiated. To identify explanatory factors, a multivariable multilevel logistic regression model was used, and adjusted odds ratios were reported. RESULTS: Overall, 1 539 003 new prescriptions were issued to 715 895 children. The overall prevalence of 1-month noninitiation was 9.0% (ranging from 2.6% [oral antibiotics] to 21.5% [proton pump inhibitors]), and the prevalence of 6-month noninitiation was 8.5%. Noninitiation was higher in the youngest and oldest population groups, in children from families with a 0% copayment rate (vulnerable populations) and those with conditions from external causes. Out-of-pocket costs of drugs increased the odds of noninitiation. The odds of noninitiation were lower when the prescription was issued by a pediatrician (compared with a primary or secondary care clinician). CONCLUSIONS: The prevalence of noninitiation of medical treatments in pediatrics is high and varies according to patients&#39; ages and medical groups. Results suggest that there are inequities in access to pharmacologic treatments in this population that must be taken into account by health care planners and providers. [ABSTRACT FROM AUTHOR]
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  Data: &lt;i&gt;Copyright of Pediatrics is the property of American Academy of Pediatrics and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1542/peds.2020-034371
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 11
        StartPage: 48
    Subjects:
      – SubjectFull: Scientific observation
        Type: general
      – SubjectFull: Health services accessibility
        Type: general
      – SubjectFull: Multivariate analysis
        Type: general
      – SubjectFull: Medical care costs
        Type: general
      – SubjectFull: Drug administration
        Type: general
      – SubjectFull: Health behavior
        Type: general
      – SubjectFull: Drugs
        Type: general
      – SubjectFull: At-risk people
        Type: general
      – SubjectFull: Patient compliance
        Type: general
      – SubjectFull: Logistic regression analysis
        Type: general
      – SubjectFull: Odds ratio
        Type: general
      – SubjectFull: Spain
        Type: general
    Titles:
      – TitleFull: Pediatric Medication Noninitiation in Spain.
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            NameFull: Carbonell-Duacastella, Cristina
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            NameFull: Rubio-Valera, Maria
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            NameFull: Marqués-Ercilla, Sílvia
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            NameFull: Penarrubia-María, Maria Teresa
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            NameFull: Gil-Girbau, Montserrat
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            NameFull: Garcia-Cardenas, Victoria
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            NameFull: Pasarín, Maria Isabel
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            NameFull: Parody-Rúa, Elizabeth
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            – D: 01
              M: 01
              Text: Jan2022
              Type: published
              Y: 2022
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