Pediatric Medication Noninitiation in Spain.
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| Title: | Pediatric Medication Noninitiation in Spain. |
|---|---|
| Authors: | Carbonell-Duacastella, Cristina, Rubio-Valera, Maria, Marqués-Ercilla, Sílvia, Penarrubia-María, Maria Teresa, Gil-Girbau, Montserrat, Garcia-Cardenas, Victoria, Pasarín, Maria Isabel, Parody-Rúa, Elizabeth, Aznar-Lou, Ignacio |
| Source: | Pediatrics. Jan2022, Vol. 149 Issue 1, p48-58. 11p. |
| Subjects: | Scientific observation, Health services accessibility, Multivariate analysis, Medical care costs, Drug administration, Health behavior, Drugs, At-risk people, Patient compliance, Logistic regression analysis, Odds ratio |
| Geographic Terms: | Spain |
| Abstract: | OBJECTIVES: To estimate medication noninitiation prevalence in the pediatric population and identify the explanatory factors underlying this behavior. METHODS: Observational study of patients (<18 years old) receiving at least 1 new prescription (28 pharmaceutical subgroups; July 2017 to June 2018) in Catalonia, Spain. A prescription was considered new when there was no prescription for the same pharmaceutical subgroup in the previous 6 months. Noninitiation occurred when a prescription was not filled within 1 month or 6 months (sensitivity analysis). Prevalence was estimated as the proportion of total prescriptions not initiated. To identify explanatory factors, a multivariable multilevel logistic regression model was used, and adjusted odds ratios were reported. RESULTS: Overall, 1 539 003 new prescriptions were issued to 715 895 children. The overall prevalence of 1-month noninitiation was 9.0% (ranging from 2.6% [oral antibiotics] to 21.5% [proton pump inhibitors]), and the prevalence of 6-month noninitiation was 8.5%. Noninitiation was higher in the youngest and oldest population groups, in children from families with a 0% copayment rate (vulnerable populations) and those with conditions from external causes. Out-of-pocket costs of drugs increased the odds of noninitiation. The odds of noninitiation were lower when the prescription was issued by a pediatrician (compared with a primary or secondary care clinician). CONCLUSIONS: The prevalence of noninitiation of medical treatments in pediatrics is high and varies according to patients' ages and medical groups. Results suggest that there are inequities in access to pharmacologic treatments in this population that must be taken into account by health care planners and providers. [ABSTRACT FROM AUTHOR] |
| Copyright of Pediatrics is the property of American Academy of Pediatrics and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
| FullText | Text: Availability: 0 |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 154493059 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Pediatric Medication Noninitiation in Spain. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Carbonell-Duacastella%2C+Cristina%22">Carbonell-Duacastella, Cristina</searchLink><br /><searchLink fieldCode="AR" term="%22Rubio-Valera%2C+Maria%22">Rubio-Valera, Maria</searchLink><br /><searchLink fieldCode="AR" term="%22Marqués-Ercilla%2C+Sílvia%22">Marqués-Ercilla, Sílvia</searchLink><br /><searchLink fieldCode="AR" term="%22Penarrubia-María%2C+Maria+Teresa%22">Penarrubia-María, Maria Teresa</searchLink><br /><searchLink fieldCode="AR" term="%22Gil-Girbau%2C+Montserrat%22">Gil-Girbau, Montserrat</searchLink><br /><searchLink fieldCode="AR" term="%22Garcia-Cardenas%2C+Victoria%22">Garcia-Cardenas, Victoria</searchLink><br /><searchLink fieldCode="AR" term="%22Pasarín%2C+Maria+Isabel%22">Pasarín, Maria Isabel</searchLink><br /><searchLink fieldCode="AR" term="%22Parody-Rúa%2C+Elizabeth%22">Parody-Rúa, Elizabeth</searchLink><br /><searchLink fieldCode="AR" term="%22Aznar-Lou%2C+Ignacio%22">Aznar-Lou, Ignacio</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Pediatrics%22">Pediatrics</searchLink>. Jan2022, Vol. 149 Issue 1, p48-58. 11p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Scientific+observation%22">Scientific observation</searchLink><br /><searchLink fieldCode="DE" term="%22Health+services+accessibility%22">Health services accessibility</searchLink><br /><searchLink fieldCode="DE" term="%22Multivariate+analysis%22">Multivariate analysis</searchLink><br /><searchLink fieldCode="DE" term="%22Medical+care+costs%22">Medical care costs</searchLink><br /><searchLink fieldCode="DE" term="%22Drug+administration%22">Drug administration</searchLink><br /><searchLink fieldCode="DE" term="%22Health+behavior%22">Health behavior</searchLink><br /><searchLink fieldCode="DE" term="%22Drugs%22">Drugs</searchLink><br /><searchLink fieldCode="DE" term="%22At-risk+people%22">At-risk people</searchLink><br /><searchLink fieldCode="DE" term="%22Patient+compliance%22">Patient compliance</searchLink><br /><searchLink fieldCode="DE" term="%22Logistic+regression+analysis%22">Logistic regression analysis</searchLink><br /><searchLink fieldCode="DE" term="%22Odds+ratio%22">Odds ratio</searchLink> – Name: SubjectGeographic Label: Geographic Terms Group: Su Data: <searchLink fieldCode="DE" term="%22Spain%22">Spain</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: OBJECTIVES: To estimate medication noninitiation prevalence in the pediatric population and identify the explanatory factors underlying this behavior. METHODS: Observational study of patients (<18 years old) receiving at least 1 new prescription (28 pharmaceutical subgroups; July 2017 to June 2018) in Catalonia, Spain. A prescription was considered new when there was no prescription for the same pharmaceutical subgroup in the previous 6 months. Noninitiation occurred when a prescription was not filled within 1 month or 6 months (sensitivity analysis). Prevalence was estimated as the proportion of total prescriptions not initiated. To identify explanatory factors, a multivariable multilevel logistic regression model was used, and adjusted odds ratios were reported. RESULTS: Overall, 1 539 003 new prescriptions were issued to 715 895 children. The overall prevalence of 1-month noninitiation was 9.0% (ranging from 2.6% [oral antibiotics] to 21.5% [proton pump inhibitors]), and the prevalence of 6-month noninitiation was 8.5%. Noninitiation was higher in the youngest and oldest population groups, in children from families with a 0% copayment rate (vulnerable populations) and those with conditions from external causes. Out-of-pocket costs of drugs increased the odds of noninitiation. The odds of noninitiation were lower when the prescription was issued by a pediatrician (compared with a primary or secondary care clinician). CONCLUSIONS: The prevalence of noninitiation of medical treatments in pediatrics is high and varies according to patients' ages and medical groups. Results suggest that there are inequities in access to pharmacologic treatments in this population that must be taken into account by health care planners and providers. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Pediatrics is the property of American Academy of Pediatrics and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1542/peds.2020-034371 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 11 StartPage: 48 Subjects: – SubjectFull: Scientific observation Type: general – SubjectFull: Health services accessibility Type: general – SubjectFull: Multivariate analysis Type: general – SubjectFull: Medical care costs Type: general – SubjectFull: Drug administration Type: general – SubjectFull: Health behavior Type: general – SubjectFull: Drugs Type: general – SubjectFull: At-risk people Type: general – SubjectFull: Patient compliance Type: general – SubjectFull: Logistic regression analysis Type: general – SubjectFull: Odds ratio Type: general – SubjectFull: Spain Type: general Titles: – TitleFull: Pediatric Medication Noninitiation in Spain. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Carbonell-Duacastella, Cristina – PersonEntity: Name: NameFull: Rubio-Valera, Maria – PersonEntity: Name: NameFull: Marqués-Ercilla, Sílvia – PersonEntity: Name: NameFull: Penarrubia-María, Maria Teresa – PersonEntity: Name: NameFull: Gil-Girbau, Montserrat – PersonEntity: Name: NameFull: Garcia-Cardenas, Victoria – PersonEntity: Name: NameFull: Pasarín, Maria Isabel – PersonEntity: Name: NameFull: Parody-Rúa, Elizabeth – PersonEntity: Name: NameFull: Aznar-Lou, Ignacio IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 01 Text: Jan2022 Type: published Y: 2022 Identifiers: – Type: issn-print Value: 00314005 Numbering: – Type: volume Value: 149 – Type: issue Value: 1 Titles: – TitleFull: Pediatrics Type: main |
| ResultId | 1 |