Antenatal depressive symptoms in Kenyan women living with HIV: contributions of recent HIV diagnosis, stigma, and partner violence.

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Title: Antenatal depressive symptoms in Kenyan women living with HIV: contributions of recent HIV diagnosis, stigma, and partner violence.
Authors: Osborn, Lusi, Ronen, Keshet, Larsen, Anna M., Richardson, Barbra, Khasimwa, Brian, Chohan, Bhavna, Matemo, Daniel, Unger, Jennifer, Drake, Alison L., Kinuthia, John, John-Stewart, Grace
Source: AIDS Care. Jan 2022, Vol. 34 Issue 1, p69-77. 9p. 1 Diagram, 2 Charts.
Subjects: Diagnosis of mental depression, Maternal health services, Pregnancy & psychology, Attitudes of mothers, Cross-sectional method, Social stigma, Medical screening, Intimate partner violence, Questionnaires, Descriptive statistics, Prenatal care, Women's health, Psychology of HIV-positive persons, Vertical transmission (Communicable diseases), Pregnancy
Geographic Terms: Sub-Saharan Africa, Kenya
Abstract: Depression among pregnant women living with HIV (WLWH) in sub-Saharan Africa leads to poor pregnancy and HIV outcomes. This cross-sectional analysis utilized enrollment data from a randomized trial (Mobile WAChX, NCT02400671) in six Kenyan public maternal and child health clinics. Depressive symptoms were assessed with the Patient Health Questionnaire-9 (PHQ-9), stigma with the Stigma Scale for Chronic Illness, and intimate partner violence (IPV) with the Abuse Assessment Screen. Correlates of moderate-to-severe depressive symptoms ("depression", PHQ-9 score ≥10) were assessed using generalized estimating equation models clustered by facility. Among 824 pregnant WLWH, 9% had depression; these women had more recent HIV diagnosis than those without depression (median 0.4 vs. 2.0 years since diagnosis, p =.008). Depression was associated with HIV-related stigma (adjusted Prevalence Ratio [aPR]:2.36, p =.025), IPV (aPR:2.93, p =.002), and lower social support score (aPR:0.99, p =.023). Using population-attributable risk percent to estimate contributors to maternal depression, 81% were attributable to stigma (27%), recent diagnosis (24%), and IPV (20%). Integrating depression screening and treatment in prevention of mother-to-child HIV transmission programs may be beneficial, particularly in women recently diagnosed or reporting stigma and IPV. [ABSTRACT FROM AUTHOR]
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  Data: Antenatal depressive symptoms in Kenyan women living with HIV: contributions of recent HIV diagnosis, stigma, and partner violence.
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  Data: <searchLink fieldCode="AR" term="%22Osborn%2C+Lusi%22">Osborn, Lusi</searchLink><br /><searchLink fieldCode="AR" term="%22Ronen%2C+Keshet%22">Ronen, Keshet</searchLink><br /><searchLink fieldCode="AR" term="%22Larsen%2C+Anna+M%2E%22">Larsen, Anna M.</searchLink><br /><searchLink fieldCode="AR" term="%22Richardson%2C+Barbra%22">Richardson, Barbra</searchLink><br /><searchLink fieldCode="AR" term="%22Khasimwa%2C+Brian%22">Khasimwa, Brian</searchLink><br /><searchLink fieldCode="AR" term="%22Chohan%2C+Bhavna%22">Chohan, Bhavna</searchLink><br /><searchLink fieldCode="AR" term="%22Matemo%2C+Daniel%22">Matemo, Daniel</searchLink><br /><searchLink fieldCode="AR" term="%22Unger%2C+Jennifer%22">Unger, Jennifer</searchLink><br /><searchLink fieldCode="AR" term="%22Drake%2C+Alison+L%2E%22">Drake, Alison L.</searchLink><br /><searchLink fieldCode="AR" term="%22Kinuthia%2C+John%22">Kinuthia, John</searchLink><br /><searchLink fieldCode="AR" term="%22John-Stewart%2C+Grace%22">John-Stewart, Grace</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22AIDS+Care%22">AIDS Care</searchLink>. Jan 2022, Vol. 34 Issue 1, p69-77. 9p. 1 Diagram, 2 Charts.
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  Data: <searchLink fieldCode="DE" term="%22Diagnosis+of+mental+depression%22">Diagnosis of mental depression</searchLink><br /><searchLink fieldCode="DE" term="%22Maternal+health+services%22">Maternal health services</searchLink><br /><searchLink fieldCode="DE" term="%22Pregnancy+%26+psychology%22">Pregnancy & psychology</searchLink><br /><searchLink fieldCode="DE" term="%22Attitudes+of+mothers%22">Attitudes of mothers</searchLink><br /><searchLink fieldCode="DE" term="%22Cross-sectional+method%22">Cross-sectional method</searchLink><br /><searchLink fieldCode="DE" term="%22Social+stigma%22">Social stigma</searchLink><br /><searchLink fieldCode="DE" term="%22Medical+screening%22">Medical screening</searchLink><br /><searchLink fieldCode="DE" term="%22Intimate+partner+violence%22">Intimate partner violence</searchLink><br /><searchLink fieldCode="DE" term="%22Questionnaires%22">Questionnaires</searchLink><br /><searchLink fieldCode="DE" term="%22Descriptive+statistics%22">Descriptive statistics</searchLink><br /><searchLink fieldCode="DE" term="%22Prenatal+care%22">Prenatal care</searchLink><br /><searchLink fieldCode="DE" term="%22Women's+health%22">Women's health</searchLink><br /><searchLink fieldCode="DE" term="%22Psychology+of+HIV-positive+persons%22">Psychology of HIV-positive persons</searchLink><br /><searchLink fieldCode="DE" term="%22Vertical+transmission+%28Communicable+diseases%29%22">Vertical transmission (Communicable diseases)</searchLink><br /><searchLink fieldCode="DE" term="%22Pregnancy%22">Pregnancy</searchLink>
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  Data: <searchLink fieldCode="DE" term="%22Sub-Saharan+Africa%22">Sub-Saharan Africa</searchLink><br /><searchLink fieldCode="DE" term="%22Kenya%22">Kenya</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Depression among pregnant women living with HIV (WLWH) in sub-Saharan Africa leads to poor pregnancy and HIV outcomes. This cross-sectional analysis utilized enrollment data from a randomized trial (Mobile WAChX, NCT02400671) in six Kenyan public maternal and child health clinics. Depressive symptoms were assessed with the Patient Health Questionnaire-9 (PHQ-9), stigma with the Stigma Scale for Chronic Illness, and intimate partner violence (IPV) with the Abuse Assessment Screen. Correlates of moderate-to-severe depressive symptoms ("depression", PHQ-9 score ≥10) were assessed using generalized estimating equation models clustered by facility. Among 824 pregnant WLWH, 9% had depression; these women had more recent HIV diagnosis than those without depression (median 0.4 vs. 2.0 years since diagnosis, p =.008). Depression was associated with HIV-related stigma (adjusted Prevalence Ratio [aPR]:2.36, p =.025), IPV (aPR:2.93, p =.002), and lower social support score (aPR:0.99, p =.023). Using population-attributable risk percent to estimate contributors to maternal depression, 81% were attributable to stigma (27%), recent diagnosis (24%), and IPV (20%). Integrating depression screening and treatment in prevention of mother-to-child HIV transmission programs may be beneficial, particularly in women recently diagnosed or reporting stigma and IPV. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of AIDS Care is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
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    Identifiers:
      – Type: doi
        Value: 10.1080/09540121.2021.1981216
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      – Code: eng
        Text: English
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        PageCount: 9
        StartPage: 69
    Subjects:
      – SubjectFull: Diagnosis of mental depression
        Type: general
      – SubjectFull: Maternal health services
        Type: general
      – SubjectFull: Pregnancy & psychology
        Type: general
      – SubjectFull: Attitudes of mothers
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      – SubjectFull: Cross-sectional method
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      – SubjectFull: Social stigma
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      – SubjectFull: Medical screening
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      – SubjectFull: Intimate partner violence
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      – SubjectFull: Questionnaires
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      – SubjectFull: Descriptive statistics
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      – SubjectFull: Prenatal care
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      – SubjectFull: Women's health
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      – SubjectFull: Psychology of HIV-positive persons
        Type: general
      – SubjectFull: Vertical transmission (Communicable diseases)
        Type: general
      – SubjectFull: Pregnancy
        Type: general
      – SubjectFull: Sub-Saharan Africa
        Type: general
      – SubjectFull: Kenya
        Type: general
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      – TitleFull: Antenatal depressive symptoms in Kenyan women living with HIV: contributions of recent HIV diagnosis, stigma, and partner violence.
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              Text: Jan 2022
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