View in EDS HTML Full Text PDF Full Text

Determining prognostic variables of treatment outcome in obsessive–compulsive disorder: effectiveness and its predictors in routine clinical care.

Saved in:
Bibliographic Details
Title: Determining prognostic variables of treatment outcome in obsessive–compulsive disorder: effectiveness and its predictors in routine clinical care.
Authors: Herzog, Philipp (AUTHOR), Osen, Bernhard (AUTHOR), Stierle, Christian (AUTHOR), Middendorf, Thomas (AUTHOR), Voderholzer, Ulrich (AUTHOR), Koch, Stefan (AUTHOR), Feldmann, Matthias (AUTHOR), Rief, Winfried (AUTHOR), Brakemeier, Eva-Lotta (AUTHOR)
Source: European Archives of Psychiatry & Clinical Neuroscience. Mar2022, Vol. 272 Issue 2, p313-326. 14p. 1 Diagram, 3 Charts.
Subjects: Obsessive-compulsive disorder, Treatment effectiveness, Evidence-based psychotherapy, Clinical medicine, Psychotherapists, Multiple regression analysis, Tic disorders
Abstract: The objectives of this study were to investigate the naturalistic effectiveness of routine inpatient treatment for patients with obsessive–compulsive disorder (OCD) and to identify predictors of treatment outcome. A routinely collected data set of 1,596 OCD inpatients (M = 33.9 years, SD = 11.7; 60.4% female) having received evidence-based psychotherapy based on the cognitive–behavioral therapy (CBT) in five German psychotherapeutic clinics was analyzed. Effect sizes (Hedges' g) were calculated for several outcome variables to determine effectiveness. Predictor analyses were performed on a subsample (N = 514; M = 34.3 years, SD = 12.2; 60.3% female). For this purpose, the number of potential predictors was reduced using factor analysis, followed by multiple regression analysis to identify robust predictors. Effect sizes of various outcome variables could be classified as large (g = 1.34 of OCD–symptom change). Predictors of changes in OCD and depressive symptoms were symptom severity at admission and general psychopathological distress. In addition, patients with higher social support and more washing compulsions benefited more from treatment. Subgroup analyses showed a distinct predictor profile of changes in compulsions and obsessions. The results indicate that an evidence-based psychotherapy program for OCD can be effectively implemented in routine inpatient care. In addition to well-established predictors, social support, and washing compulsions in particular were identified as important positive predictors. Specific predictor profiles for changes in obsessions and compulsions are discussed. [ABSTRACT FROM AUTHOR]
Copyright of European Archives of Psychiatry & Clinical Neuroscience is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: pbh
DbLabel: Psychology and Behavioral Sciences Collection
An: 155397142
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Determining prognostic variables of treatment outcome in obsessive–compulsive disorder: effectiveness and its predictors in routine clinical care.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Herzog%2C+Philipp%22">Herzog, Philipp</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Osen%2C+Bernhard%22">Osen, Bernhard</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Stierle%2C+Christian%22">Stierle, Christian</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Middendorf%2C+Thomas%22">Middendorf, Thomas</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Voderholzer%2C+Ulrich%22">Voderholzer, Ulrich</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Koch%2C+Stefan%22">Koch, Stefan</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Feldmann%2C+Matthias%22">Feldmann, Matthias</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Rief%2C+Winfried%22">Rief, Winfried</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Brakemeier%2C+Eva-Lotta%22">Brakemeier, Eva-Lotta</searchLink> (AUTHOR)
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22European+Archives+of+Psychiatry+%26+Clinical+Neuroscience%22">European Archives of Psychiatry & Clinical Neuroscience</searchLink>. Mar2022, Vol. 272 Issue 2, p313-326. 14p. 1 Diagram, 3 Charts.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Obsessive-compulsive+disorder%22">Obsessive-compulsive disorder</searchLink><br /><searchLink fieldCode="DE" term="%22Treatment+effectiveness%22">Treatment effectiveness</searchLink><br /><searchLink fieldCode="DE" term="%22Evidence-based+psychotherapy%22">Evidence-based psychotherapy</searchLink><br /><searchLink fieldCode="DE" term="%22Clinical+medicine%22">Clinical medicine</searchLink><br /><searchLink fieldCode="DE" term="%22Psychotherapists%22">Psychotherapists</searchLink><br /><searchLink fieldCode="DE" term="%22Multiple+regression+analysis%22">Multiple regression analysis</searchLink><br /><searchLink fieldCode="DE" term="%22Tic+disorders%22">Tic disorders</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: The objectives of this study were to investigate the naturalistic effectiveness of routine inpatient treatment for patients with obsessive–compulsive disorder (OCD) and to identify predictors of treatment outcome. A routinely collected data set of 1,596 OCD inpatients (M = 33.9 years, SD = 11.7; 60.4% female) having received evidence-based psychotherapy based on the cognitive–behavioral therapy (CBT) in five German psychotherapeutic clinics was analyzed. Effect sizes (Hedges' g) were calculated for several outcome variables to determine effectiveness. Predictor analyses were performed on a subsample (N = 514; M = 34.3 years, SD = 12.2; 60.3% female). For this purpose, the number of potential predictors was reduced using factor analysis, followed by multiple regression analysis to identify robust predictors. Effect sizes of various outcome variables could be classified as large (g = 1.34 of OCD–symptom change). Predictors of changes in OCD and depressive symptoms were symptom severity at admission and general psychopathological distress. In addition, patients with higher social support and more washing compulsions benefited more from treatment. Subgroup analyses showed a distinct predictor profile of changes in compulsions and obsessions. The results indicate that an evidence-based psychotherapy program for OCD can be effectively implemented in routine inpatient care. In addition to well-established predictors, social support, and washing compulsions in particular were identified as important positive predictors. Specific predictor profiles for changes in obsessions and compulsions are discussed. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of European Archives of Psychiatry & Clinical Neuroscience is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=155397142
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1007/s00406-021-01284-6
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 14
        StartPage: 313
    Subjects:
      – SubjectFull: Obsessive-compulsive disorder
        Type: general
      – SubjectFull: Treatment effectiveness
        Type: general
      – SubjectFull: Evidence-based psychotherapy
        Type: general
      – SubjectFull: Clinical medicine
        Type: general
      – SubjectFull: Psychotherapists
        Type: general
      – SubjectFull: Multiple regression analysis
        Type: general
      – SubjectFull: Tic disorders
        Type: general
    Titles:
      – TitleFull: Determining prognostic variables of treatment outcome in obsessive–compulsive disorder: effectiveness and its predictors in routine clinical care.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Herzog, Philipp
      – PersonEntity:
          Name:
            NameFull: Osen, Bernhard
      – PersonEntity:
          Name:
            NameFull: Stierle, Christian
      – PersonEntity:
          Name:
            NameFull: Middendorf, Thomas
      – PersonEntity:
          Name:
            NameFull: Voderholzer, Ulrich
      – PersonEntity:
          Name:
            NameFull: Koch, Stefan
      – PersonEntity:
          Name:
            NameFull: Feldmann, Matthias
      – PersonEntity:
          Name:
            NameFull: Rief, Winfried
      – PersonEntity:
          Name:
            NameFull: Brakemeier, Eva-Lotta
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 03
              Text: Mar2022
              Type: published
              Y: 2022
          Identifiers:
            – Type: issn-print
              Value: 09401334
          Numbering:
            – Type: volume
              Value: 272
            – Type: issue
              Value: 2
          Titles:
            – TitleFull: European Archives of Psychiatry & Clinical Neuroscience
              Type: main
ResultId 1