Early childhood adversity and late-life depressive symptoms: unpacking mediation and interaction by adult socioeconomic status.
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| Title: | Early childhood adversity and late-life depressive symptoms: unpacking mediation and interaction by adult socioeconomic status. |
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| Authors: | Yazawa, Aki (AUTHOR), Shiba, Koichiro (AUTHOR), Inoue, Yosuke (AUTHOR), Okuzono, Sakurako S. (AUTHOR), Inoue, Kosuke (AUTHOR), Kondo, Naoki (AUTHOR), Kondo, Katsunori (AUTHOR), Kawachi, Ichiro (AUTHOR) |
| Source: | Social Psychiatry & Psychiatric Epidemiology. Jun2022, Vol. 57 Issue 6, p1147-1156. 10p. |
| Subjects: | Mental depression, Children of people with mental illness, Socioeconomic status, Geriatric Depression Scale, Older people, Adverse childhood experiences |
| Abstract: | Purpose: Adverse childhood experiences (ACEs) have been linked to diminished health achievement across the life course. However, few studies have rigorously investigated the role of adult socioeconomic status (SES) as a mediator and an effect modifier of the association between ACEs and late-life depression. We used a four-way decomposition analysis to examine the relative contributions of mediation and interaction by low adult SES to the association between ACEs and late-life depression. Methods: Data came from two waves (2013 and 2016) of the Japan Gerontological Evaluation Study, a nationwide cohort of older people (n = 7271). ACEs were determined as ≥ 2 experiences of the following: parental loss, parental divorce, parental mental illness, domestic violence, physical abuse, psychological neglect, psychological abuse, and economic disadvantage. Low adult SES was defined as earning < 2 million yen of income and < 10 years of schooling. Depressive symptoms were assessed using the Geriatric Depression Scale. Results: Controlled direct effect (coefficient 0.28; 95% CI 0.08–0.46) accounted for 69.1% of the total effect, which was greater than the other three estimates for the decomposed effects (reference interaction 20.8%, mediated interaction 5.7%, and pure indirect effect 4.4%). Adult SES accounted for 10.1% (via mediation) and 26.5% (via exposure–mediator interaction) of the total association between ACEs and depressive symptoms, respectively. Conclusion: ACEs appeared to be a strong and independent determinant of depressive symptoms in later life. Nonetheless, the interaction between ACEs and adult SES indicates that achieving high adult SES could mitigate the adverse effect of ACEs on late-life depression. [ABSTRACT FROM AUTHOR] |
| Copyright of Social Psychiatry & Psychiatric Epidemiology is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 156789242 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Early childhood adversity and late-life depressive symptoms: unpacking mediation and interaction by adult socioeconomic status. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Yazawa%2C+Aki%22">Yazawa, Aki</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Shiba%2C+Koichiro%22">Shiba, Koichiro</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Inoue%2C+Yosuke%22">Inoue, Yosuke</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Okuzono%2C+Sakurako+S%2E%22">Okuzono, Sakurako S.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Inoue%2C+Kosuke%22">Inoue, Kosuke</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kondo%2C+Naoki%22">Kondo, Naoki</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kondo%2C+Katsunori%22">Kondo, Katsunori</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kawachi%2C+Ichiro%22">Kawachi, Ichiro</searchLink> (AUTHOR) – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Social+Psychiatry+%26+Psychiatric+Epidemiology%22">Social Psychiatry & Psychiatric Epidemiology</searchLink>. Jun2022, Vol. 57 Issue 6, p1147-1156. 10p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Mental+depression%22">Mental depression</searchLink><br /><searchLink fieldCode="DE" term="%22Children+of+people+with+mental+illness%22">Children of people with mental illness</searchLink><br /><searchLink fieldCode="DE" term="%22Socioeconomic+status%22">Socioeconomic status</searchLink><br /><searchLink fieldCode="DE" term="%22Geriatric+Depression+Scale%22">Geriatric Depression Scale</searchLink><br /><searchLink fieldCode="DE" term="%22Older+people%22">Older people</searchLink><br /><searchLink fieldCode="DE" term="%22Adverse+childhood+experiences%22">Adverse childhood experiences</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Purpose: Adverse childhood experiences (ACEs) have been linked to diminished health achievement across the life course. However, few studies have rigorously investigated the role of adult socioeconomic status (SES) as a mediator and an effect modifier of the association between ACEs and late-life depression. We used a four-way decomposition analysis to examine the relative contributions of mediation and interaction by low adult SES to the association between ACEs and late-life depression. Methods: Data came from two waves (2013 and 2016) of the Japan Gerontological Evaluation Study, a nationwide cohort of older people (n = 7271). ACEs were determined as ≥ 2 experiences of the following: parental loss, parental divorce, parental mental illness, domestic violence, physical abuse, psychological neglect, psychological abuse, and economic disadvantage. Low adult SES was defined as earning < 2 million yen of income and < 10 years of schooling. Depressive symptoms were assessed using the Geriatric Depression Scale. Results: Controlled direct effect (coefficient 0.28; 95% CI 0.08–0.46) accounted for 69.1% of the total effect, which was greater than the other three estimates for the decomposed effects (reference interaction 20.8%, mediated interaction 5.7%, and pure indirect effect 4.4%). Adult SES accounted for 10.1% (via mediation) and 26.5% (via exposure–mediator interaction) of the total association between ACEs and depressive symptoms, respectively. Conclusion: ACEs appeared to be a strong and independent determinant of depressive symptoms in later life. Nonetheless, the interaction between ACEs and adult SES indicates that achieving high adult SES could mitigate the adverse effect of ACEs on late-life depression. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Social Psychiatry & Psychiatric Epidemiology is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s00127-022-02241-x Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 10 StartPage: 1147 Subjects: – SubjectFull: Mental depression Type: general – SubjectFull: Children of people with mental illness Type: general – SubjectFull: Socioeconomic status Type: general – SubjectFull: Geriatric Depression Scale Type: general – SubjectFull: Older people Type: general – SubjectFull: Adverse childhood experiences Type: general Titles: – TitleFull: Early childhood adversity and late-life depressive symptoms: unpacking mediation and interaction by adult socioeconomic status. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Yazawa, Aki – PersonEntity: Name: NameFull: Shiba, Koichiro – PersonEntity: Name: NameFull: Inoue, Yosuke – PersonEntity: Name: NameFull: Okuzono, Sakurako S. – PersonEntity: Name: NameFull: Inoue, Kosuke – PersonEntity: Name: NameFull: Kondo, Naoki – PersonEntity: Name: NameFull: Kondo, Katsunori – PersonEntity: Name: NameFull: Kawachi, Ichiro IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 06 Text: Jun2022 Type: published Y: 2022 Identifiers: – Type: issn-print Value: 09337954 Numbering: – Type: volume Value: 57 – Type: issue Value: 6 Titles: – TitleFull: Social Psychiatry & Psychiatric Epidemiology Type: main |
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