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Childhood poverty, immune cell aging, and African Americans' insulin resistance: A prospective study.

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Title: Childhood poverty, immune cell aging, and African Americans' insulin resistance: A prospective study.
Authors: Barton, Allen W. (AUTHOR), Yu, Tianyi (AUTHOR), Gong, Qiujie (AUTHOR), Miller, Gregory E. (AUTHOR), Chen, Edith (AUTHOR), Brody, Gene H. (AUTHOR)
Source: Child Development. Sep2022, Vol. 93 Issue 5, p1616-1624. 9p. 2 Diagrams, 1 Chart.
Subjects: Poor children, Insulin resistance, African American youth, Cellular aging, Life chances, Immune system aging, Chronic disease risk factors
Abstract: The present study investigated developmental pathways that can contribute to chronic disease among rural African Americans. With a sample of 342 African American youth (59% female) from the southeastern United States followed for nearly two decades (2001–2019), we examined the prospective association between family poverty during adolescence (ages 11–18) and insulin resistance (IR) in young adulthood (ages 25–29) as well as underlying biological and psychosocial mechanisms. Results indicated family poverty during adolescence forecast higher levels of IR in young adulthood, with accelerated immune cell aging at age 20 partially mediating this association. Serial mediational models confirmed the hypothesized pathway linking family poverty, perceived life chances, cellular aging, and IR. Findings provide empirical support for theorized developmental precursors of chronic disease. [ABSTRACT FROM AUTHOR]
Copyright of Child Development is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Childhood poverty, immune cell aging, and African Americans' insulin resistance: A prospective study.
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  Data: <searchLink fieldCode="AR" term="%22Barton%2C+Allen+W%2E%22">Barton, Allen W.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Yu%2C+Tianyi%22">Yu, Tianyi</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Gong%2C+Qiujie%22">Gong, Qiujie</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Miller%2C+Gregory+E%2E%22">Miller, Gregory E.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Chen%2C+Edith%22">Chen, Edith</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Brody%2C+Gene+H%2E%22">Brody, Gene H.</searchLink> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22Child+Development%22">Child Development</searchLink>. Sep2022, Vol. 93 Issue 5, p1616-1624. 9p. 2 Diagrams, 1 Chart.
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  Data: <searchLink fieldCode="DE" term="%22Poor+children%22">Poor children</searchLink><br /><searchLink fieldCode="DE" term="%22Insulin+resistance%22">Insulin resistance</searchLink><br /><searchLink fieldCode="DE" term="%22African+American+youth%22">African American youth</searchLink><br /><searchLink fieldCode="DE" term="%22Cellular+aging%22">Cellular aging</searchLink><br /><searchLink fieldCode="DE" term="%22Life+chances%22">Life chances</searchLink><br /><searchLink fieldCode="DE" term="%22Immune+system+aging%22">Immune system aging</searchLink><br /><searchLink fieldCode="DE" term="%22Chronic+disease+risk+factors%22">Chronic disease risk factors</searchLink>
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  Data: The present study investigated developmental pathways that can contribute to chronic disease among rural African Americans. With a sample of 342 African American youth (59% female) from the southeastern United States followed for nearly two decades (2001–2019), we examined the prospective association between family poverty during adolescence (ages 11–18) and insulin resistance (IR) in young adulthood (ages 25–29) as well as underlying biological and psychosocial mechanisms. Results indicated family poverty during adolescence forecast higher levels of IR in young adulthood, with accelerated immune cell aging at age 20 partially mediating this association. Serial mediational models confirmed the hypothesized pathway linking family poverty, perceived life chances, cellular aging, and IR. Findings provide empirical support for theorized developmental precursors of chronic disease. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Child Development is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=158809983
RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1111/cdev.13795
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      – Code: eng
        Text: English
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        PageCount: 9
        StartPage: 1616
    Subjects:
      – SubjectFull: Poor children
        Type: general
      – SubjectFull: Insulin resistance
        Type: general
      – SubjectFull: African American youth
        Type: general
      – SubjectFull: Cellular aging
        Type: general
      – SubjectFull: Life chances
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      – SubjectFull: Immune system aging
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      – SubjectFull: Chronic disease risk factors
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              M: 09
              Text: Sep2022
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              Y: 2022
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