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Effects of reversible cognitive frailty on disability, quality of life, depression, and hospitalization: a prospective cohort study.

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Title: Effects of reversible cognitive frailty on disability, quality of life, depression, and hospitalization: a prospective cohort study.
Authors: Wang, Wenyu, Si, Huaxin, Yu, Ruby, Qiao, Xiaoxia, Jin, Yaru, Ji, Lili, Liu, Qinqin, Bian, Yanhui, Yu, Jiaqi, Wang, Cuili
Source: Aging & Mental Health. Oct2022, Vol. 26 Issue 10, p2031-2038. 8p. 1 Diagram, 2 Charts.
Subjects: Mental depression risk factors, Frail elderly, Mild cognitive impairment, Self-evaluation, Activities of daily living, Functional assessment, Risk assessment, Quality of life, Hospital care, Independent living, Questionnaires, Descriptive statistics, Odds ratio, Longitudinal method, Disease complications
Geographic Terms: China
Abstract: Cognitive frailty, a potentially reversible condition describing the concurrence of physical frailty and mild cognitive impairment (MCI), has been recently proposed to incorporate subjective cognitive decline (SCD), a reversible pre-MCI state with more readily available cognitive reserve, as well as pre-physical frailty. Reversible cognitive frailty has been associated with dementia and mortality. We aimed to examine the association of reversible cognitive frailty with other adverse outcomes including disability, poor quality of life (QOL), depression, and hospitalization. This was a cohort study with 1-year follow-up among 735 Chinese community-dwelling older adults with intact cognition. Reversible cognitive frailty was operationalized with the presence of pre-physical or physical frailty identified by the Frailty Phenotype and SCD identified by the simplified SCD questionnaire including four self-report cognitive domains of memory, naming, orientation, and mathematical reasoning. Adverse outcomes included incident Activities of Daily Living (ADL)-Instrumental ADL (IADL) disability, poor physical, mental and overall QOL, depression, and hospitalization over 1-year follow-up. The prevalence of reversible cognitive frailty was 27.8%. Participants with reversible cognitive frailty had higher risk of the incidence of ADL-IADL disability, poor physical QOL, poor mental QOL, poor overall QOL, and depression (Odds Ratios: 1.67–4.38, P < 0.05), but not higher risk of hospitalization over 1-year follow-up. Reversible cognitive frailty was not uncommon and associated with incident disability, poor QOL, and depression among community-dwelling older adults. Early identification of reversible cognitive frailty can facilitate targeted interventions and may promote independence in older adults. Supplemental data for this article is available online at http://dx.doi.org/10.1080/13607863.2021.2011835 [ABSTRACT FROM AUTHOR]
Copyright of Aging & Mental Health is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Cognitive frailty, a potentially reversible condition describing the concurrence of physical frailty and mild cognitive impairment (MCI), has been recently proposed to incorporate subjective cognitive decline (SCD), a reversible pre-MCI state with more readily available cognitive reserve, as well as pre-physical frailty. Reversible cognitive frailty has been associated with dementia and mortality. We aimed to examine the association of reversible cognitive frailty with other adverse outcomes including disability, poor quality of life (QOL), depression, and hospitalization. This was a cohort study with 1-year follow-up among 735 Chinese community-dwelling older adults with intact cognition. Reversible cognitive frailty was operationalized with the presence of pre-physical or physical frailty identified by the Frailty Phenotype and SCD identified by the simplified SCD questionnaire including four self-report cognitive domains of memory, naming, orientation, and mathematical reasoning. Adverse outcomes included incident Activities of Daily Living (ADL)-Instrumental ADL (IADL) disability, poor physical, mental and overall QOL, depression, and hospitalization over 1-year follow-up. The prevalence of reversible cognitive frailty was 27.8%. Participants with reversible cognitive frailty had higher risk of the incidence of ADL-IADL disability, poor physical QOL, poor mental QOL, poor overall QOL, and depression (Odds Ratios: 1.67–4.38, P &lt; 0.05), but not higher risk of hospitalization over 1-year follow-up. Reversible cognitive frailty was not uncommon and associated with incident disability, poor QOL, and depression among community-dwelling older adults. Early identification of reversible cognitive frailty can facilitate targeted interventions and may promote independence in older adults. Supplemental data for this article is available online at http://dx.doi.org/10.1080/13607863.2021.2011835 [ABSTRACT FROM AUTHOR]
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  Data: &lt;i&gt;Copyright of Aging &amp; Mental Health is the property of Taylor &amp; Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1080/13607863.2021.2011835
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 8
        StartPage: 2031
    Subjects:
      – SubjectFull: Mental depression risk factors
        Type: general
      – SubjectFull: Frail elderly
        Type: general
      – SubjectFull: Mild cognitive impairment
        Type: general
      – SubjectFull: Self-evaluation
        Type: general
      – SubjectFull: Activities of daily living
        Type: general
      – SubjectFull: Functional assessment
        Type: general
      – SubjectFull: Risk assessment
        Type: general
      – SubjectFull: Quality of life
        Type: general
      – SubjectFull: Hospital care
        Type: general
      – SubjectFull: Independent living
        Type: general
      – SubjectFull: Questionnaires
        Type: general
      – SubjectFull: Descriptive statistics
        Type: general
      – SubjectFull: Odds ratio
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      – SubjectFull: Longitudinal method
        Type: general
      – SubjectFull: Disease complications
        Type: general
      – SubjectFull: China
        Type: general
    Titles:
      – TitleFull: Effects of reversible cognitive frailty on disability, quality of life, depression, and hospitalization: a prospective cohort study.
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            – D: 01
              M: 10
              Text: Oct2022
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