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Impaired delay discounting and time sensitivity in methcathinone use disorder.

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Title: Impaired delay discounting and time sensitivity in methcathinone use disorder.
Authors: Zeng, Ningning (AUTHOR), Zheng, Hui (AUTHOR), Shi, Tianshu (AUTHOR), Zhang, Hang-Bin (AUTHOR), Wang, Li-Xun (AUTHOR), Liang, Zhu-Yuan (AUTHOR), Sun, Bomin (AUTHOR), Liao, Yanhui (AUTHOR), Rao, Li-Lin (AUTHOR), Yang, Bo (AUTHOR), Yuan, Ti-Fei (AUTHOR)
Source: European Archives of Psychiatry & Clinical Neuroscience. Dec2022, Vol. 272 Issue 8, p1595-1602. 8p. 1 Chart, 4 Graphs.
Subjects: Delay discounting (Psychology), Time perception, Task performance, Substance abuse, Drug utilization, Decision making
Abstract: Substance use disorder (SUD) is characterized by continued drug use despite adverse consequences. Methcathinone is a new type of psychoactive substance that is associated with high excitement and impulsive behaviors. However, it is unclear if individuals with methcathinone use disorders (MCUD) are with impaired decision-making ability. We analyzed the task performance in 45 male MCUD subjects and 35 male matched healthy controls (HC) with intertemporal decision-making task. Constant sensitivity discounting model was used to estimate potential changes in both discounting rate and time sensitivity. The results showed that MCUD individuals exhibited a higher delay discounting rate (p = 0.003, Cohen's d = 0.683) and reduced sensitivity to time (p < 0.001, Cohen's d = 1.662). The delay discounting rate was correlated to the first age for drug use (r = − 0.41, p = 0.004), and the time sensitivity was negatively correlated with the duration of abstinence (r = − 0.31, p = 0.036). We conclude that MCUD individuals are with impaired decision-making ability and time perception disturbances. [ABSTRACT FROM AUTHOR]
Copyright of European Archives of Psychiatry & Clinical Neuroscience is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Impaired delay discounting and time sensitivity in methcathinone use disorder.
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  Data: Substance use disorder (SUD) is characterized by continued drug use despite adverse consequences. Methcathinone is a new type of psychoactive substance that is associated with high excitement and impulsive behaviors. However, it is unclear if individuals with methcathinone use disorders (MCUD) are with impaired decision-making ability. We analyzed the task performance in 45 male MCUD subjects and 35 male matched healthy controls (HC) with intertemporal decision-making task. Constant sensitivity discounting model was used to estimate potential changes in both discounting rate and time sensitivity. The results showed that MCUD individuals exhibited a higher delay discounting rate (p = 0.003, Cohen&#39;s d = 0.683) and reduced sensitivity to time (p &lt; 0.001, Cohen&#39;s d = 1.662). The delay discounting rate was correlated to the first age for drug use (r = − 0.41, p = 0.004), and the time sensitivity was negatively correlated with the duration of abstinence (r = − 0.31, p = 0.036). We conclude that MCUD individuals are with impaired decision-making ability and time perception disturbances. [ABSTRACT FROM AUTHOR]
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  Data: &lt;i&gt;Copyright of European Archives of Psychiatry &amp; Clinical Neuroscience is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
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        Value: 10.1007/s00406-021-01372-7
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      – Code: eng
        Text: English
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      – SubjectFull: Delay discounting (Psychology)
        Type: general
      – SubjectFull: Time perception
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              Text: Dec2022
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