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Menopausal hormone therapy and the risk of cataracts in postmenopausal women in South Korea.

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Title: Menopausal hormone therapy and the risk of cataracts in postmenopausal women in South Korea.
Authors: Yuk, Jin‐Sung (AUTHOR), Park, Jae Yong (AUTHOR), Sim, Ha Eun (AUTHOR), Hwang, Je Hyung (AUTHOR)
Source: Ophthalmic & Physiological Optics. Mar2023, Vol. 43 Issue 2, p254-262. 9p. 2 Diagrams, 3 Charts.
Subjects: Postmenopause, Hormone therapy, Cataract, Alcohol drinking, Ratio analysis
Geographic Terms: South Korea
Abstract: Purpose: Postmenopausal women have a higher prevalence of cataracts than men of a similar age. This study aimed to evaluate the effects of menopausal hormone therapy (MHT) on lens opacities in postmenopausal women. Methods: This retrospective cohort study analysed population‐based health insurance data in South Korea collected from 2002 to 2019. To determine the risk factors associated with cataract, postmenopausal women (N = 2,506,271) were grouped according to post‐MHT use. The treatment group was further divided into the following subgroups: tibolone, combined oestrogen plus progestin by manufacturer, oral oestrogen, combined oestrogen plus progestin by physician and topical oestrogen groups. The main outcome measure was the prevalence of cataracts. Results: The control group comprised 463,151 postmenopausal women who had never used MHT after menopause, while the treatment group included 228,033 postmenopausal women who had used MHT continuously for at least 6 months. The treatment group had a higher incidence of cataracts than the control group based on Cox proportional hazards ratio analysis. Low socioeconomic status and high parity were identified as risk factors for cataracts, and reduced risk of cataracts was associated with living in rural areas and drinking alcohol. Conclusions: Women undergoing post‐MHT, including tibolone, had a higher incidence of cataracts. Cataract development should be a concern when examining postmenopausal patients using MHT. [ABSTRACT FROM AUTHOR]
Copyright of Ophthalmic & Physiological Optics is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Menopausal hormone therapy and the risk of cataracts in postmenopausal women in South Korea.
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  Data: <searchLink fieldCode="AR" term="%22Yuk%2C+Jin‐Sung%22">Yuk, Jin‐Sung</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Park%2C+Jae+Yong%22">Park, Jae Yong</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Sim%2C+Ha+Eun%22">Sim, Ha Eun</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Hwang%2C+Je+Hyung%22">Hwang, Je Hyung</searchLink> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22Ophthalmic+%26+Physiological+Optics%22">Ophthalmic & Physiological Optics</searchLink>. Mar2023, Vol. 43 Issue 2, p254-262. 9p. 2 Diagrams, 3 Charts.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Postmenopause%22">Postmenopause</searchLink><br /><searchLink fieldCode="DE" term="%22Hormone+therapy%22">Hormone therapy</searchLink><br /><searchLink fieldCode="DE" term="%22Cataract%22">Cataract</searchLink><br /><searchLink fieldCode="DE" term="%22Alcohol+drinking%22">Alcohol drinking</searchLink><br /><searchLink fieldCode="DE" term="%22Ratio+analysis%22">Ratio analysis</searchLink>
– Name: SubjectGeographic
  Label: Geographic Terms
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  Data: <searchLink fieldCode="DE" term="%22South+Korea%22">South Korea</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Purpose: Postmenopausal women have a higher prevalence of cataracts than men of a similar age. This study aimed to evaluate the effects of menopausal hormone therapy (MHT) on lens opacities in postmenopausal women. Methods: This retrospective cohort study analysed population‐based health insurance data in South Korea collected from 2002 to 2019. To determine the risk factors associated with cataract, postmenopausal women (N = 2,506,271) were grouped according to post‐MHT use. The treatment group was further divided into the following subgroups: tibolone, combined oestrogen plus progestin by manufacturer, oral oestrogen, combined oestrogen plus progestin by physician and topical oestrogen groups. The main outcome measure was the prevalence of cataracts. Results: The control group comprised 463,151 postmenopausal women who had never used MHT after menopause, while the treatment group included 228,033 postmenopausal women who had used MHT continuously for at least 6 months. The treatment group had a higher incidence of cataracts than the control group based on Cox proportional hazards ratio analysis. Low socioeconomic status and high parity were identified as risk factors for cataracts, and reduced risk of cataracts was associated with living in rural areas and drinking alcohol. Conclusions: Women undergoing post‐MHT, including tibolone, had a higher incidence of cataracts. Cataract development should be a concern when examining postmenopausal patients using MHT. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Ophthalmic & Physiological Optics is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1111/opo.13089
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      – Code: eng
        Text: English
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        PageCount: 9
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      – SubjectFull: Postmenopause
        Type: general
      – SubjectFull: Hormone therapy
        Type: general
      – SubjectFull: Cataract
        Type: general
      – SubjectFull: Alcohol drinking
        Type: general
      – SubjectFull: Ratio analysis
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      – SubjectFull: South Korea
        Type: general
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      – TitleFull: Menopausal hormone therapy and the risk of cataracts in postmenopausal women in South Korea.
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            NameFull: Yuk, Jin‐Sung
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            NameFull: Park, Jae Yong
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            NameFull: Sim, Ha Eun
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              M: 03
              Text: Mar2023
              Type: published
              Y: 2023
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