View in EDS HTML Full Text PDF Full Text

Anorexia nervosa and muscle health: A systematic review of our current understanding and future recommendations for study.

Saved in:
Bibliographic Details
Title: Anorexia nervosa and muscle health: A systematic review of our current understanding and future recommendations for study.
Authors: Rosa‐Caldwell, Megan E., Eddy, Kamryn T., Rutkove, Seward B., Breithaupt, Lauren
Source: International Journal of Eating Disorders. Mar2023, Vol. 56 Issue 3, p483-500. 18p. 1 Diagram, 1 Chart, 1 Graph.
Subjects: Skeletal muscle physiology, Online information services, Energy metabolism, Skeletal muscle, Systematic reviews, Lean body mass, Weight gain, Muscle strength, Descriptive statistics, Research funding, Anorexia nervosa, MEDLINE
Abstract (English): Objective: Conduct a systematic review on muscle size and strength in individuals with anorexia nervosa (AN). Method: In accordance with PRISMA guidelines, we searched Pubmed for articles published between 1995 and 2022 using a combination of search terms related to AN and muscle size, strength, or metabolism. After two authors screened articles and extracted data, 30 articles met inclusion criteria. Data were coded, and a risk bias was conducted for each study. Results: The majority of studies focused on muscle size/lean mass (60%, n = 18) and energy expenditure (33%, n = 9), with few studies (17%, n = 5) investigating muscle function or possible mechanisms underlying muscle size (20%, n = 6). Studies supported that individuals with AN have smaller muscle size and reduced energy expenditure relative to controls. In some studies (33%, n = 10) recovery from AN was not sufficient to restore muscle mass or function. Mechanisms underlying short and long‐term musculoskeletal alterations have not been thoroughly explored. Discussion: Muscle mass and strength loss may be an unexplored component of physiological deterioration during and after AN. More research is necessary to understand intramuscular alterations during AN and interventions to facilitate muscle mass and functional gain following weight restoration in AN. Public Significance: Muscle health is important for optimal health and is reduced in individuals with AN. However, we do not understand how muscle is altered at the cellular level throughout the course of AN. Here we review what is currently known regarding muscle health during AN and with weight restoration. [ABSTRACT FROM AUTHOR]
Abstract (Spanish): Résumé: Objetivo: Realizar una revisión sistemática sobre el tamaño y la fuerza muscular en individuos que padecen anorexia nerviosa (AN). Método: De acuerdo con las guías PRISMA, se realizaron búsquedas en Pubmed de artículos publicados entre 1995 y 2022 mediante una combinación de términos de búsqueda relacionados con la anorexia nerviosa y el tamaño, la fuerza o el metabolismo muscular. Después de que dos autores examinaron los artículos y extrajeron los datos, 30 artículos cumplieron los criterios de inclusión. Se codificaron los datos y se realizó un sesgo de riesgo para cada estudio. Resultados: La mayoría de los estudios se enfocaron en el tamaño muscular/masa magra (60%, n=18) y el gasto energético (33%, n=9), con pocos estudios (17%, n=5) investigando la función muscular o los posibles mecanismos subyacentes al tamaño muscular (20%, n=6). Los estudios apoyaron que los individuos que padecen anorexia nerviosa tienen un tamaño muscular más pequeño y un gasto de energía reducido en relación con los controles. En algunos estudios (33%, n = 10) la recuperación de la anorexia nerviosa no fue suficiente para restaurar la masa muscular o la función. Los mecanismos subyacentes a las alteraciones musculoesqueléticas a corto y largo plazo no se han explorado a fondo. Discusión: La pérdida de masa muscular y fuerza puede ser un componente inexplorado del deterioro fisiológico durante y después de la AN. Se necesita más investigación para comprender las alteraciones intramusculares durante la anorexia nerviosa y las intervenciones para facilitar la masa muscular y la ganancia funcional después de la restauración del peso en la anorexia nerviosa. [ABSTRACT FROM AUTHOR]
Copyright of International Journal of Eating Disorders is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: pbh
DbLabel: Psychology and Behavioral Sciences Collection
An: 162168238
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Anorexia nervosa and muscle health: A systematic review of our current understanding and future recommendations for study.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Rosa‐Caldwell%2C+Megan+E%2E%22">Rosa‐Caldwell, Megan E.</searchLink><br /><searchLink fieldCode="AR" term="%22Eddy%2C+Kamryn+T%2E%22">Eddy, Kamryn T.</searchLink><br /><searchLink fieldCode="AR" term="%22Rutkove%2C+Seward+B%2E%22">Rutkove, Seward B.</searchLink><br /><searchLink fieldCode="AR" term="%22Breithaupt%2C+Lauren%22">Breithaupt, Lauren</searchLink>
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22International+Journal+of+Eating+Disorders%22">International Journal of Eating Disorders</searchLink>. Mar2023, Vol. 56 Issue 3, p483-500. 18p. 1 Diagram, 1 Chart, 1 Graph.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Skeletal+muscle+physiology%22">Skeletal muscle physiology</searchLink><br /><searchLink fieldCode="DE" term="%22Online+information+services%22">Online information services</searchLink><br /><searchLink fieldCode="DE" term="%22Energy+metabolism%22">Energy metabolism</searchLink><br /><searchLink fieldCode="DE" term="%22Skeletal+muscle%22">Skeletal muscle</searchLink><br /><searchLink fieldCode="DE" term="%22Systematic+reviews%22">Systematic reviews</searchLink><br /><searchLink fieldCode="DE" term="%22Lean+body+mass%22">Lean body mass</searchLink><br /><searchLink fieldCode="DE" term="%22Weight+gain%22">Weight gain</searchLink><br /><searchLink fieldCode="DE" term="%22Muscle+strength%22">Muscle strength</searchLink><br /><searchLink fieldCode="DE" term="%22Descriptive+statistics%22">Descriptive statistics</searchLink><br /><searchLink fieldCode="DE" term="%22Research+funding%22">Research funding</searchLink><br /><searchLink fieldCode="DE" term="%22Anorexia+nervosa%22">Anorexia nervosa</searchLink><br /><searchLink fieldCode="DE" term="%22MEDLINE%22">MEDLINE</searchLink>
– Name: Abstract
  Label: Abstract (English)
  Group: Ab
  Data: Objective: Conduct a systematic review on muscle size and strength in individuals with anorexia nervosa (AN). Method: In accordance with PRISMA guidelines, we searched Pubmed for articles published between 1995 and 2022 using a combination of search terms related to AN and muscle size, strength, or metabolism. After two authors screened articles and extracted data, 30 articles met inclusion criteria. Data were coded, and a risk bias was conducted for each study. Results: The majority of studies focused on muscle size/lean mass (60%, n = 18) and energy expenditure (33%, n = 9), with few studies (17%, n = 5) investigating muscle function or possible mechanisms underlying muscle size (20%, n = 6). Studies supported that individuals with AN have smaller muscle size and reduced energy expenditure relative to controls. In some studies (33%, n = 10) recovery from AN was not sufficient to restore muscle mass or function. Mechanisms underlying short and long‐term musculoskeletal alterations have not been thoroughly explored. Discussion: Muscle mass and strength loss may be an unexplored component of physiological deterioration during and after AN. More research is necessary to understand intramuscular alterations during AN and interventions to facilitate muscle mass and functional gain following weight restoration in AN. Public Significance: Muscle health is important for optimal health and is reduced in individuals with AN. However, we do not understand how muscle is altered at the cellular level throughout the course of AN. Here we review what is currently known regarding muscle health during AN and with weight restoration. [ABSTRACT FROM AUTHOR]
– Name: Abstract
  Label: Abstract (Spanish)
  Group: Ab
  Data: Résumé: Objetivo: Realizar una revisión sistemática sobre el tamaño y la fuerza muscular en individuos que padecen anorexia nerviosa (AN). Método: De acuerdo con las guías PRISMA, se realizaron búsquedas en Pubmed de artículos publicados entre 1995 y 2022 mediante una combinación de términos de búsqueda relacionados con la anorexia nerviosa y el tamaño, la fuerza o el metabolismo muscular. Después de que dos autores examinaron los artículos y extrajeron los datos, 30 artículos cumplieron los criterios de inclusión. Se codificaron los datos y se realizó un sesgo de riesgo para cada estudio. Resultados: La mayoría de los estudios se enfocaron en el tamaño muscular/masa magra (60%, n=18) y el gasto energético (33%, n=9), con pocos estudios (17%, n=5) investigando la función muscular o los posibles mecanismos subyacentes al tamaño muscular (20%, n=6). Los estudios apoyaron que los individuos que padecen anorexia nerviosa tienen un tamaño muscular más pequeño y un gasto de energía reducido en relación con los controles. En algunos estudios (33%, n = 10) la recuperación de la anorexia nerviosa no fue suficiente para restaurar la masa muscular o la función. Los mecanismos subyacentes a las alteraciones musculoesqueléticas a corto y largo plazo no se han explorado a fondo. Discusión: La pérdida de masa muscular y fuerza puede ser un componente inexplorado del deterioro fisiológico durante y después de la AN. Se necesita más investigación para comprender las alteraciones intramusculares durante la anorexia nerviosa y las intervenciones para facilitar la masa muscular y la ganancia funcional después de la restauración del peso en la anorexia nerviosa. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of International Journal of Eating Disorders is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=162168238
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1002/eat.23878
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 18
        StartPage: 483
    Subjects:
      – SubjectFull: Skeletal muscle physiology
        Type: general
      – SubjectFull: Online information services
        Type: general
      – SubjectFull: Energy metabolism
        Type: general
      – SubjectFull: Skeletal muscle
        Type: general
      – SubjectFull: Systematic reviews
        Type: general
      – SubjectFull: Lean body mass
        Type: general
      – SubjectFull: Weight gain
        Type: general
      – SubjectFull: Muscle strength
        Type: general
      – SubjectFull: Descriptive statistics
        Type: general
      – SubjectFull: Research funding
        Type: general
      – SubjectFull: Anorexia nervosa
        Type: general
      – SubjectFull: MEDLINE
        Type: general
    Titles:
      – TitleFull: Anorexia nervosa and muscle health: A systematic review of our current understanding and future recommendations for study.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Rosa‐Caldwell, Megan E.
      – PersonEntity:
          Name:
            NameFull: Eddy, Kamryn T.
      – PersonEntity:
          Name:
            NameFull: Rutkove, Seward B.
      – PersonEntity:
          Name:
            NameFull: Breithaupt, Lauren
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 03
              Text: Mar2023
              Type: published
              Y: 2023
          Identifiers:
            – Type: issn-print
              Value: 02763478
          Numbering:
            – Type: volume
              Value: 56
            – Type: issue
              Value: 3
          Titles:
            – TitleFull: International Journal of Eating Disorders
              Type: main
ResultId 1