Asthma.

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Bibliographic Details
Title: Asthma.
Authors: Porsbjerg, Celeste (AUTHOR), Melén, Erik (AUTHOR), Lehtimäki, Lauri (AUTHOR), Shaw, Dominick (AUTHOR)
Source: Lancet. Mar2023, Vol. 401 Issue 10379, p858-873. 16p.
Subjects: Asthma, Non-communicable diseases, Asthmatics, Wheeze, Asthma-related mortality, Disease remission, Biotherapy
Abstract: Asthma is one of the most common chronic non-communicable diseases worldwide and is characterised by variable airflow obstruction, causing dyspnoea and wheezing. Highly effective therapies are available; asthma morbidity and mortality have vastly improved in the past 15 years, and most patients can attain good asthma control. However, undertreatment is still common, and improving patient and health-care provider understanding of when and how to adjust treatment is crucial. Asthma management consists of a cycle of assessment of asthma control and risk factors and adjustment of medications accordingly. With the introduction of biological therapies, management of severe asthma has entered the precision medicine era—a shift that is driving clinical ambitions towards disease remission. Patients with severe asthma often have co-existing conditions contributing to their symptoms, mandating a multidimensional management approach. In this Seminar, we provide a clinically focused overview of asthma; epidemiology, pathophysiology, diagnosis, and management in children and adults. [ABSTRACT FROM AUTHOR]
Copyright of Lancet is the property of Lancet and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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PubType: Academic Journal
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  Data: Asthma.
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  Data: <searchLink fieldCode="AR" term="%22Porsbjerg%2C+Celeste%22">Porsbjerg, Celeste</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Melén%2C+Erik%22">Melén, Erik</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Lehtimäki%2C+Lauri%22">Lehtimäki, Lauri</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Shaw%2C+Dominick%22">Shaw, Dominick</searchLink> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22Lancet%22">Lancet</searchLink>. Mar2023, Vol. 401 Issue 10379, p858-873. 16p.
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  Data: <searchLink fieldCode="DE" term="%22Asthma%22">Asthma</searchLink><br /><searchLink fieldCode="DE" term="%22Non-communicable+diseases%22">Non-communicable diseases</searchLink><br /><searchLink fieldCode="DE" term="%22Asthmatics%22">Asthmatics</searchLink><br /><searchLink fieldCode="DE" term="%22Wheeze%22">Wheeze</searchLink><br /><searchLink fieldCode="DE" term="%22Asthma-related+mortality%22">Asthma-related mortality</searchLink><br /><searchLink fieldCode="DE" term="%22Disease+remission%22">Disease remission</searchLink><br /><searchLink fieldCode="DE" term="%22Biotherapy%22">Biotherapy</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Asthma is one of the most common chronic non-communicable diseases worldwide and is characterised by variable airflow obstruction, causing dyspnoea and wheezing. Highly effective therapies are available; asthma morbidity and mortality have vastly improved in the past 15 years, and most patients can attain good asthma control. However, undertreatment is still common, and improving patient and health-care provider understanding of when and how to adjust treatment is crucial. Asthma management consists of a cycle of assessment of asthma control and risk factors and adjustment of medications accordingly. With the introduction of biological therapies, management of severe asthma has entered the precision medicine era—a shift that is driving clinical ambitions towards disease remission. Patients with severe asthma often have co-existing conditions contributing to their symptoms, mandating a multidimensional management approach. In this Seminar, we provide a clinically focused overview of asthma; epidemiology, pathophysiology, diagnosis, and management in children and adults. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
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  Group: Ab
  Data: <i>Copyright of Lancet is the property of Lancet and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
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    Identifiers:
      – Type: doi
        Value: 10.1016/S0140-6736(22)02125-0
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      – Code: eng
        Text: English
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      Pagination:
        PageCount: 16
        StartPage: 858
    Subjects:
      – SubjectFull: Asthma
        Type: general
      – SubjectFull: Non-communicable diseases
        Type: general
      – SubjectFull: Asthmatics
        Type: general
      – SubjectFull: Wheeze
        Type: general
      – SubjectFull: Asthma-related mortality
        Type: general
      – SubjectFull: Disease remission
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      – SubjectFull: Biotherapy
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      – TitleFull: Asthma.
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            NameFull: Porsbjerg, Celeste
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            NameFull: Melén, Erik
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            NameFull: Lehtimäki, Lauri
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            NameFull: Shaw, Dominick
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            – D: 11
              M: 03
              Text: Mar2023
              Type: published
              Y: 2023
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