Associations between the prevalence of chronic hepatitis B among people who inject drugs and country‐level characteristics: An ecological analysis.
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| Title: | Associations between the prevalence of chronic hepatitis B among people who inject drugs and country‐level characteristics: An ecological analysis. |
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| Authors: | Syangbo, Anjalee (AUTHOR), Hickman, Matthew (AUTHOR), Colledge‐Frisby, Samantha (AUTHOR), Leung, Janni (AUTHOR), Grebely, Jason (AUTHOR), Larney, Sarah (AUTHOR), Degenhardt, Louisa (AUTHOR), Trickey, Adam (AUTHOR) |
| Source: | Drug & Alcohol Review. Mar2023, Vol. 42 Issue 3, p569-581. 13p. 4 Charts, 2 Graphs, 1 Map. |
| Subjects: | Chronic hepatitis B, Disease prevalence, Hepatitis B virus, Hepatitis C virus, Hepatitis B vaccines |
| Geographic Terms: | Southeast Asia, Western Europe |
| Abstract: | Introduction: Globally, hepatitis B virus (HBV) is a leading cause of liver disease. People who inject drugs (PWID) are at greater risk than the general population of contracting HBV. This risk could depend on societal factors in different countries. We investigated the associations between country‐level chronic HBV prevalence in PWID with national indicators of development and prevalence of HIV and hepatitis C virus (HCV). Methods: We used global systematic review data on chronic HBV prevalence (hepatitis B surface antigen‐positive) among PWID and country‐level sociodemographic characteristics from online databases. National random‐effects meta‐analysis estimates of HBV prevalence were the outcome in linear regression models testing for associations with country‐level characteristics. Results: The study included 131,710 PWID from 304 estimates in 55 countries: the pooled HBV prevalence among PWID in the countries analysed was 4.5% (95% CI 3.9–5.1), the highest regional pooled prevalence was in East and Southeast Asia (17.6% [13.3–22.3]), and the lowest was in Western Europe (1.7% [1.4–2.1]). In multivariable models, no indicators of development were associated with HBV prevalence, but there was evidence of positive associations between HBV prevalence in the general population and among PWID, and evidence of HIV and HCV prevalence in PWID being associated with HBV prevalence in PWID: multivariable coefficients 0.03 (95% CI 0.01–0.04); p < 0.001, and 0.01 (95% CI 0.00–0.03); p = 0.01, respectively. Discussion and Conclusions: HBV prevalence among PWID was associated with HIV and HCV prevalence among PWID and background HBV prevalence in the general population, highlighting the need for improving harm reduction in PWID and implementation of HBV vaccination, especially where HBV is endemic. [ABSTRACT FROM AUTHOR] |
| Copyright of Drug & Alcohol Review is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 162569472 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Associations between the prevalence of chronic hepatitis B among people who inject drugs and country‐level characteristics: An ecological analysis. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Syangbo%2C+Anjalee%22">Syangbo, Anjalee</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Hickman%2C+Matthew%22">Hickman, Matthew</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Colledge‐Frisby%2C+Samantha%22">Colledge‐Frisby, Samantha</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Leung%2C+Janni%22">Leung, Janni</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Grebely%2C+Jason%22">Grebely, Jason</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Larney%2C+Sarah%22">Larney, Sarah</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Degenhardt%2C+Louisa%22">Degenhardt, Louisa</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Trickey%2C+Adam%22">Trickey, Adam</searchLink> (AUTHOR) – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Drug+%26+Alcohol+Review%22">Drug & Alcohol Review</searchLink>. Mar2023, Vol. 42 Issue 3, p569-581. 13p. 4 Charts, 2 Graphs, 1 Map. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Chronic+hepatitis+B%22">Chronic hepatitis B</searchLink><br /><searchLink fieldCode="DE" term="%22Disease+prevalence%22">Disease prevalence</searchLink><br /><searchLink fieldCode="DE" term="%22Hepatitis+B+virus%22">Hepatitis B virus</searchLink><br /><searchLink fieldCode="DE" term="%22Hepatitis+C+virus%22">Hepatitis C virus</searchLink><br /><searchLink fieldCode="DE" term="%22Hepatitis+B+vaccines%22">Hepatitis B vaccines</searchLink> – Name: SubjectGeographic Label: Geographic Terms Group: Su Data: <searchLink fieldCode="DE" term="%22Southeast+Asia%22">Southeast Asia</searchLink><br /><searchLink fieldCode="DE" term="%22Western+Europe%22">Western Europe</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Introduction: Globally, hepatitis B virus (HBV) is a leading cause of liver disease. People who inject drugs (PWID) are at greater risk than the general population of contracting HBV. This risk could depend on societal factors in different countries. We investigated the associations between country‐level chronic HBV prevalence in PWID with national indicators of development and prevalence of HIV and hepatitis C virus (HCV). Methods: We used global systematic review data on chronic HBV prevalence (hepatitis B surface antigen‐positive) among PWID and country‐level sociodemographic characteristics from online databases. National random‐effects meta‐analysis estimates of HBV prevalence were the outcome in linear regression models testing for associations with country‐level characteristics. Results: The study included 131,710 PWID from 304 estimates in 55 countries: the pooled HBV prevalence among PWID in the countries analysed was 4.5% (95% CI 3.9–5.1), the highest regional pooled prevalence was in East and Southeast Asia (17.6% [13.3–22.3]), and the lowest was in Western Europe (1.7% [1.4–2.1]). In multivariable models, no indicators of development were associated with HBV prevalence, but there was evidence of positive associations between HBV prevalence in the general population and among PWID, and evidence of HIV and HCV prevalence in PWID being associated with HBV prevalence in PWID: multivariable coefficients 0.03 (95% CI 0.01–0.04); p < 0.001, and 0.01 (95% CI 0.00–0.03); p = 0.01, respectively. Discussion and Conclusions: HBV prevalence among PWID was associated with HIV and HCV prevalence among PWID and background HBV prevalence in the general population, highlighting the need for improving harm reduction in PWID and implementation of HBV vaccination, especially where HBV is endemic. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Drug & Alcohol Review is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1111/dar.13595 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 13 StartPage: 569 Subjects: – SubjectFull: Chronic hepatitis B Type: general – SubjectFull: Disease prevalence Type: general – SubjectFull: Hepatitis B virus Type: general – SubjectFull: Hepatitis C virus Type: general – SubjectFull: Hepatitis B vaccines Type: general – SubjectFull: Southeast Asia Type: general – SubjectFull: Western Europe Type: general Titles: – TitleFull: Associations between the prevalence of chronic hepatitis B among people who inject drugs and country‐level characteristics: An ecological analysis. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Syangbo, Anjalee – PersonEntity: Name: NameFull: Hickman, Matthew – PersonEntity: Name: NameFull: Colledge‐Frisby, Samantha – PersonEntity: Name: NameFull: Leung, Janni – PersonEntity: Name: NameFull: Grebely, Jason – PersonEntity: Name: NameFull: Larney, Sarah – PersonEntity: Name: NameFull: Degenhardt, Louisa – PersonEntity: Name: NameFull: Trickey, Adam IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 03 Text: Mar2023 Type: published Y: 2023 Identifiers: – Type: issn-print Value: 09595236 Numbering: – Type: volume Value: 42 – Type: issue Value: 3 Titles: – TitleFull: Drug & Alcohol Review Type: main |
| ResultId | 1 |
