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Video directly observed therapy to improve adherence of human immunodeficiency virus infected adolescents to combination antiretroviral therapy: a proof-of-concept study.

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Title: Video directly observed therapy to improve adherence of human immunodeficiency virus infected adolescents to combination antiretroviral therapy: a proof-of-concept study.
Authors: Kordy, Faisal, Nashid, Nancy, Khan, Sarah, Read, Stanley, Macdougall, Georgina, Louch, Debra, Arneson, Cheryl, Bitnun, Ari
Source: AIDS Care. Mar2023, Vol. 35 Issue 3, p417-424. 8p. 3 Charts, 1 Graph.
Subjects: HIV infections, HIV-positive persons, Pilot projects, Directly observed therapy, Combination drug therapy, Viral load, Videoconferencing, Antiretroviral agents, Patient satisfaction, Quality assurance, Drugs, Questionnaires, Patient compliance, Text messages, Longitudinal method, Therapeutics, Adolescence
Abstract: Adherence to antiretroviral therapy (ART) is a major challenge for many youth living with HIV (YLWH). In this prospective proof-of-concept study, we assessed the feasibility and acceptability of conducting a study of video directly observed therapy (VDOT) as a method of improving medication adherence in YLWH who had a history of poor adherence to ART. The study had four phases; phase I – VDOT daily (4 months) using Facetime®; phase II – daily texting (2 months); phase III – weekly texting (3 months); phase IV – no intervention (3 months). Participants were seen in clinic on a monthly basis for assessment and laboratory evaluation. Five of eight eligible participants were enrolled. All achieved virologic suppression one month after enrollment. Three of five completed the study protocol and maintained virologic suppression through the 12-month period of study. Participant responses to the end-of-study questionnaire indicated satisfaction with the intervention and thought VDOT was helpful to them. Healthcare providers thought that the intervention was effective for some youth but was at times burdensome. This proof-of-concept study demonstrated that VDOT may be effective at improving medication adherence in previously poorly adherent YLWH and that larger studies of VDOT for such patients are both feasible and warranted. [ABSTRACT FROM AUTHOR]
Copyright of AIDS Care is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Label: Title
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  Data: Video directly observed therapy to improve adherence of human immunodeficiency virus infected adolescents to combination antiretroviral therapy: a proof-of-concept study.
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  Data: <searchLink fieldCode="AR" term="%22Kordy%2C+Faisal%22">Kordy, Faisal</searchLink><br /><searchLink fieldCode="AR" term="%22Nashid%2C+Nancy%22">Nashid, Nancy</searchLink><br /><searchLink fieldCode="AR" term="%22Khan%2C+Sarah%22">Khan, Sarah</searchLink><br /><searchLink fieldCode="AR" term="%22Read%2C+Stanley%22">Read, Stanley</searchLink><br /><searchLink fieldCode="AR" term="%22Macdougall%2C+Georgina%22">Macdougall, Georgina</searchLink><br /><searchLink fieldCode="AR" term="%22Louch%2C+Debra%22">Louch, Debra</searchLink><br /><searchLink fieldCode="AR" term="%22Arneson%2C+Cheryl%22">Arneson, Cheryl</searchLink><br /><searchLink fieldCode="AR" term="%22Bitnun%2C+Ari%22">Bitnun, Ari</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22AIDS+Care%22">AIDS Care</searchLink>. Mar2023, Vol. 35 Issue 3, p417-424. 8p. 3 Charts, 1 Graph.
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  Data: <searchLink fieldCode="DE" term="%22HIV+infections%22">HIV infections</searchLink><br /><searchLink fieldCode="DE" term="%22HIV-positive+persons%22">HIV-positive persons</searchLink><br /><searchLink fieldCode="DE" term="%22Pilot+projects%22">Pilot projects</searchLink><br /><searchLink fieldCode="DE" term="%22Directly+observed+therapy%22">Directly observed therapy</searchLink><br /><searchLink fieldCode="DE" term="%22Combination+drug+therapy%22">Combination drug therapy</searchLink><br /><searchLink fieldCode="DE" term="%22Viral+load%22">Viral load</searchLink><br /><searchLink fieldCode="DE" term="%22Videoconferencing%22">Videoconferencing</searchLink><br /><searchLink fieldCode="DE" term="%22Antiretroviral+agents%22">Antiretroviral agents</searchLink><br /><searchLink fieldCode="DE" term="%22Patient+satisfaction%22">Patient satisfaction</searchLink><br /><searchLink fieldCode="DE" term="%22Quality+assurance%22">Quality assurance</searchLink><br /><searchLink fieldCode="DE" term="%22Drugs%22">Drugs</searchLink><br /><searchLink fieldCode="DE" term="%22Questionnaires%22">Questionnaires</searchLink><br /><searchLink fieldCode="DE" term="%22Patient+compliance%22">Patient compliance</searchLink><br /><searchLink fieldCode="DE" term="%22Text+messages%22">Text messages</searchLink><br /><searchLink fieldCode="DE" term="%22Longitudinal+method%22">Longitudinal method</searchLink><br /><searchLink fieldCode="DE" term="%22Therapeutics%22">Therapeutics</searchLink><br /><searchLink fieldCode="DE" term="%22Adolescence%22">Adolescence</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Adherence to antiretroviral therapy (ART) is a major challenge for many youth living with HIV (YLWH). In this prospective proof-of-concept study, we assessed the feasibility and acceptability of conducting a study of video directly observed therapy (VDOT) as a method of improving medication adherence in YLWH who had a history of poor adherence to ART. The study had four phases; phase I – VDOT daily (4 months) using Facetime®; phase II – daily texting (2 months); phase III – weekly texting (3 months); phase IV – no intervention (3 months). Participants were seen in clinic on a monthly basis for assessment and laboratory evaluation. Five of eight eligible participants were enrolled. All achieved virologic suppression one month after enrollment. Three of five completed the study protocol and maintained virologic suppression through the 12-month period of study. Participant responses to the end-of-study questionnaire indicated satisfaction with the intervention and thought VDOT was helpful to them. Healthcare providers thought that the intervention was effective for some youth but was at times burdensome. This proof-of-concept study demonstrated that VDOT may be effective at improving medication adherence in previously poorly adherent YLWH and that larger studies of VDOT for such patients are both feasible and warranted. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of AIDS Care is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1080/09540121.2022.2104794
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 8
        StartPage: 417
    Subjects:
      – SubjectFull: HIV infections
        Type: general
      – SubjectFull: HIV-positive persons
        Type: general
      – SubjectFull: Pilot projects
        Type: general
      – SubjectFull: Directly observed therapy
        Type: general
      – SubjectFull: Combination drug therapy
        Type: general
      – SubjectFull: Viral load
        Type: general
      – SubjectFull: Videoconferencing
        Type: general
      – SubjectFull: Antiretroviral agents
        Type: general
      – SubjectFull: Patient satisfaction
        Type: general
      – SubjectFull: Quality assurance
        Type: general
      – SubjectFull: Drugs
        Type: general
      – SubjectFull: Questionnaires
        Type: general
      – SubjectFull: Patient compliance
        Type: general
      – SubjectFull: Text messages
        Type: general
      – SubjectFull: Longitudinal method
        Type: general
      – SubjectFull: Therapeutics
        Type: general
      – SubjectFull: Adolescence
        Type: general
    Titles:
      – TitleFull: Video directly observed therapy to improve adherence of human immunodeficiency virus infected adolescents to combination antiretroviral therapy: a proof-of-concept study.
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            NameFull: Kordy, Faisal
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            NameFull: Nashid, Nancy
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            NameFull: Read, Stanley
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            – D: 01
              M: 03
              Text: Mar2023
              Type: published
              Y: 2023
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              Value: 09540121
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              Value: 35
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            – TitleFull: AIDS Care
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