View in EDS HTML Full Text PDF Full Text

Examining clinical correlates, treatment outcomes and mediators in young people with comorbid obsessive–compulsive disorder and autism spectrum disorder.

Saved in:
Bibliographic Details
Title: Examining clinical correlates, treatment outcomes and mediators in young people with comorbid obsessive–compulsive disorder and autism spectrum disorder.
Authors: Jassi, A. D., Vidal-Ribas, P., Krebs, G., Mataix-Cols, D., Monzani, B.
Source: European Child & Adolescent Psychiatry. Jul2023, Vol. 32 Issue 7, p1201-1210. 10p. 2 Charts, 1 Graph.
Subjects: Treatment of autism, Confidence intervals, Functional status, Treatment effectiveness, Comparative studies, Symptoms, Research funding, Questionnaires, Obsessive-compulsive disorder, Cognitive therapy, Comorbidity, Children, Adolescence
Abstract: Despite the high comorbidity, surprisingly little is known about the clinical features, treatment prognosis, and treatment mediators for youth with Obsessive–Compulsive Disorder (OCD) and Autism Spectrum Disorder (ASD). This study, the largest to date, compared 172 young people with OCD and ASD (OCD + ASD) to 447 without ASD (OCD) on clinical characteristics, finding those with OCD + ASD were more likely to endorse poorer insight into their OCD, have greater global functional impairment, greater levels of concurrent psychopathology, higher levels of family accommodation and to be on medication. Treatment outcomes following a course of Cognitive Behaviour Therapy with or without medication were explored for a subgroup; 100 young people with OCD + ASD and 223 with OCD. Whilst both groups benefitted from treatment, the OCD + ASD group had significantly poorer treatment outcomes. Greater global functional impairment and being on medication mediated the between-group difference in outcomes. Further research and treatment refinements are needed to improve outcomes for youth with OCD + ASD. [ABSTRACT FROM AUTHOR]
Copyright of European Child & Adolescent Psychiatry is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: pbh
DbLabel: Psychology and Behavioral Sciences Collection
An: 164369497
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Examining clinical correlates, treatment outcomes and mediators in young people with comorbid obsessive–compulsive disorder and autism spectrum disorder.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Jassi%2C+A%2E+D%2E%22">Jassi, A. D.</searchLink><br /><searchLink fieldCode="AR" term="%22Vidal-Ribas%2C+P%2E%22">Vidal-Ribas, P.</searchLink><br /><searchLink fieldCode="AR" term="%22Krebs%2C+G%2E%22">Krebs, G.</searchLink><br /><searchLink fieldCode="AR" term="%22Mataix-Cols%2C+D%2E%22">Mataix-Cols, D.</searchLink><br /><searchLink fieldCode="AR" term="%22Monzani%2C+B%2E%22">Monzani, B.</searchLink>
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22European+Child+%26+Adolescent+Psychiatry%22">European Child & Adolescent Psychiatry</searchLink>. Jul2023, Vol. 32 Issue 7, p1201-1210. 10p. 2 Charts, 1 Graph.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Treatment+of+autism%22">Treatment of autism</searchLink><br /><searchLink fieldCode="DE" term="%22Confidence+intervals%22">Confidence intervals</searchLink><br /><searchLink fieldCode="DE" term="%22Functional+status%22">Functional status</searchLink><br /><searchLink fieldCode="DE" term="%22Treatment+effectiveness%22">Treatment effectiveness</searchLink><br /><searchLink fieldCode="DE" term="%22Comparative+studies%22">Comparative studies</searchLink><br /><searchLink fieldCode="DE" term="%22Symptoms%22">Symptoms</searchLink><br /><searchLink fieldCode="DE" term="%22Research+funding%22">Research funding</searchLink><br /><searchLink fieldCode="DE" term="%22Questionnaires%22">Questionnaires</searchLink><br /><searchLink fieldCode="DE" term="%22Obsessive-compulsive+disorder%22">Obsessive-compulsive disorder</searchLink><br /><searchLink fieldCode="DE" term="%22Cognitive+therapy%22">Cognitive therapy</searchLink><br /><searchLink fieldCode="DE" term="%22Comorbidity%22">Comorbidity</searchLink><br /><searchLink fieldCode="DE" term="%22Children%22">Children</searchLink><br /><searchLink fieldCode="DE" term="%22Adolescence%22">Adolescence</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Despite the high comorbidity, surprisingly little is known about the clinical features, treatment prognosis, and treatment mediators for youth with Obsessive–Compulsive Disorder (OCD) and Autism Spectrum Disorder (ASD). This study, the largest to date, compared 172 young people with OCD and ASD (OCD + ASD) to 447 without ASD (OCD) on clinical characteristics, finding those with OCD + ASD were more likely to endorse poorer insight into their OCD, have greater global functional impairment, greater levels of concurrent psychopathology, higher levels of family accommodation and to be on medication. Treatment outcomes following a course of Cognitive Behaviour Therapy with or without medication were explored for a subgroup; 100 young people with OCD + ASD and 223 with OCD. Whilst both groups benefitted from treatment, the OCD + ASD group had significantly poorer treatment outcomes. Greater global functional impairment and being on medication mediated the between-group difference in outcomes. Further research and treatment refinements are needed to improve outcomes for youth with OCD + ASD. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of European Child & Adolescent Psychiatry is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=164369497
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1007/s00787-021-01921-4
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 10
        StartPage: 1201
    Subjects:
      – SubjectFull: Treatment of autism
        Type: general
      – SubjectFull: Confidence intervals
        Type: general
      – SubjectFull: Functional status
        Type: general
      – SubjectFull: Treatment effectiveness
        Type: general
      – SubjectFull: Comparative studies
        Type: general
      – SubjectFull: Symptoms
        Type: general
      – SubjectFull: Research funding
        Type: general
      – SubjectFull: Questionnaires
        Type: general
      – SubjectFull: Obsessive-compulsive disorder
        Type: general
      – SubjectFull: Cognitive therapy
        Type: general
      – SubjectFull: Comorbidity
        Type: general
      – SubjectFull: Children
        Type: general
      – SubjectFull: Adolescence
        Type: general
    Titles:
      – TitleFull: Examining clinical correlates, treatment outcomes and mediators in young people with comorbid obsessive–compulsive disorder and autism spectrum disorder.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Jassi, A. D.
      – PersonEntity:
          Name:
            NameFull: Vidal-Ribas, P.
      – PersonEntity:
          Name:
            NameFull: Krebs, G.
      – PersonEntity:
          Name:
            NameFull: Mataix-Cols, D.
      – PersonEntity:
          Name:
            NameFull: Monzani, B.
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 07
              Text: Jul2023
              Type: published
              Y: 2023
          Identifiers:
            – Type: issn-print
              Value: 10188827
          Numbering:
            – Type: volume
              Value: 32
            – Type: issue
              Value: 7
          Titles:
            – TitleFull: European Child & Adolescent Psychiatry
              Type: main
ResultId 1