Effect of Life Review Therapy for Holocaust Survivors: A randomized controlled trial.

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Title: Effect of Life Review Therapy for Holocaust Survivors: A randomized controlled trial.
Authors: Forstmeier, Simon (AUTHOR), Zimmermann, Sarah (AUTHOR), van der Hal, Elisheva (AUTHOR), Auerbach, Martin (AUTHOR), Kleinke, Kristian (AUTHOR), Maercker, Andreas (AUTHOR), Brom, Danny (AUTHOR)
Source: Journal of Traumatic Stress. Jun2023, Vol. 36 Issue 3, p628-641. 14p. 1 Diagram, 4 Charts.
Subjects: Post-traumatic stress disorder, Holocaust survivors, Randomized controlled trials, Psychoses, Older people, Mental depression
Abstract: Despite the therapeutic needs of aging Holocaust survivors, no randomized controlled trial (RCT) of psychotherapy exists for this population, with very few on older adults in general. This RCT aimed to compare the efficacy of Life Review Therapy for Holocaust survivors (LRT‐HS) relative to a supportive control group. Holocaust survivors with a probable diagnosis of full or subsyndromal posttraumatic stress disorder (PTSD) or depressive disorder were included. Exclusion criteria were probable dementia, acute psychotic disorder, and acute suicidality. The predefined primary endpoint was the course of PTSD symptom scores. In total, 49 of 79 consecutive individuals assessed for eligibility were randomized and included in the intent‐to‐treat analyses (LRT‐HS: n = 24, control: n = 25; Mage= 81.5 years, SD = 4.81, 77.6% female). Linear mixed models revealed no statistically significant superiority of LRT‐HS for PTSD symptoms at posttreatment, with moderate effect sizes, Time x Condition interaction: t(75) = 1.46, p =.148, dwithin = 0.70, dbetween = 0.41, but analyses were significant at follow‐up, with large effect sizes, t(79) = 2.89, p =.005, dwithin = 1.20, dbetween = 1.00. LRT‐HS superiority for depression was observed at posttreatment, t(73) = 2.58, p =.012, but not follow‐up, t(76) = 1.08, p =.282, with moderate effect sizes, dwithin = 0.46–0.60, dbetween = 0.53–0.70. The findings show that even in older age, PTSD and depression following exposure to multiple traumatic childhood events can be treated efficaciously using an age‐appropriate treatment that includes structured life review and narrative exposure. [ABSTRACT FROM AUTHOR]
Copyright of Journal of Traumatic Stress is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Effect of Life Review Therapy for Holocaust Survivors: A randomized controlled trial.
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  Data: <searchLink fieldCode="AR" term="%22Forstmeier%2C+Simon%22">Forstmeier, Simon</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Zimmermann%2C+Sarah%22">Zimmermann, Sarah</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22van+der+Hal%2C+Elisheva%22">van der Hal, Elisheva</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Auerbach%2C+Martin%22">Auerbach, Martin</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kleinke%2C+Kristian%22">Kleinke, Kristian</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Maercker%2C+Andreas%22">Maercker, Andreas</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Brom%2C+Danny%22">Brom, Danny</searchLink> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22Journal+of+Traumatic+Stress%22">Journal of Traumatic Stress</searchLink>. Jun2023, Vol. 36 Issue 3, p628-641. 14p. 1 Diagram, 4 Charts.
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  Data: <searchLink fieldCode="DE" term="%22Post-traumatic+stress+disorder%22">Post-traumatic stress disorder</searchLink><br /><searchLink fieldCode="DE" term="%22Holocaust+survivors%22">Holocaust survivors</searchLink><br /><searchLink fieldCode="DE" term="%22Randomized+controlled+trials%22">Randomized controlled trials</searchLink><br /><searchLink fieldCode="DE" term="%22Psychoses%22">Psychoses</searchLink><br /><searchLink fieldCode="DE" term="%22Older+people%22">Older people</searchLink><br /><searchLink fieldCode="DE" term="%22Mental+depression%22">Mental depression</searchLink>
– Name: Abstract
  Label: Abstract
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  Data: Despite the therapeutic needs of aging Holocaust survivors, no randomized controlled trial (RCT) of psychotherapy exists for this population, with very few on older adults in general. This RCT aimed to compare the efficacy of Life Review Therapy for Holocaust survivors (LRT‐HS) relative to a supportive control group. Holocaust survivors with a probable diagnosis of full or subsyndromal posttraumatic stress disorder (PTSD) or depressive disorder were included. Exclusion criteria were probable dementia, acute psychotic disorder, and acute suicidality. The predefined primary endpoint was the course of PTSD symptom scores. In total, 49 of 79 consecutive individuals assessed for eligibility were randomized and included in the intent‐to‐treat analyses (LRT‐HS: n = 24, control: n = 25; Mage= 81.5 years, SD = 4.81, 77.6% female). Linear mixed models revealed no statistically significant superiority of LRT‐HS for PTSD symptoms at posttreatment, with moderate effect sizes, Time x Condition interaction: t(75) = 1.46, p =.148, dwithin = 0.70, dbetween = 0.41, but analyses were significant at follow‐up, with large effect sizes, t(79) = 2.89, p =.005, dwithin = 1.20, dbetween = 1.00. LRT‐HS superiority for depression was observed at posttreatment, t(73) = 2.58, p =.012, but not follow‐up, t(76) = 1.08, p =.282, with moderate effect sizes, dwithin = 0.46–0.60, dbetween = 0.53–0.70. The findings show that even in older age, PTSD and depression following exposure to multiple traumatic childhood events can be treated efficaciously using an age‐appropriate treatment that includes structured life review and narrative exposure. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
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  Data: <i>Copyright of Journal of Traumatic Stress is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Value: 10.1002/jts.22933
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        Text: English
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        PageCount: 14
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      – SubjectFull: Post-traumatic stress disorder
        Type: general
      – SubjectFull: Holocaust survivors
        Type: general
      – SubjectFull: Randomized controlled trials
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      – SubjectFull: Psychoses
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      – SubjectFull: Older people
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      – SubjectFull: Mental depression
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      – TitleFull: Effect of Life Review Therapy for Holocaust Survivors: A randomized controlled trial.
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            NameFull: Forstmeier, Simon
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              M: 06
              Text: Jun2023
              Type: published
              Y: 2023
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