Pubertal timing and adolescent outcomes: investigating explanations for associations with a genetically informed design.

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Title: Pubertal timing and adolescent outcomes: investigating explanations for associations with a genetically informed design.
Authors: Padrutt, Emily R., Harper, Jeremy, Schaefer, Jonathan D., Nelson, Kayla M., McGue, Matt, Iacono, William G., Wilson, Sylia
Source: Journal of Child Psychology & Psychiatry. Aug2023, Vol. 64 Issue 8, p1232-1241. 10p. 2 Charts, 2 Graphs.
Subjects: Risk-taking behavior, Evaluation of medical care, Genetics, Substance abuse, Time, Age distribution, Puberty, Descriptive statistics, Research funding, Biometry, Adolescence
Abstract: Background: Psychopathology and risky behaviors increase during adolescence, and understanding which adolescents are most at risk informs prevention and intervention efforts. Pubertal timing relative to same‐sex, same‐age peers is a known correlate of adolescent outcomes among both boys and girls. However, it remains unclear whether this relation is better explained by a plausible causal process or unobserved familial liability. Methods: We extended previous research by examining associations between pubertal timing in early adolescence (age 14) and outcomes in later adolescence (age 17) in a community sample of 2,510 twins (49% boys, 51% girls). Results: Earlier pubertal timing was associated with more substance use, risk behavior, internalizing and externalizing problems, and peer problems in later adolescence; these effects were small, consistent with previous literature. Follow‐up co‐twin control analyses indicated that within‐twin‐pair differences in pubertal timing were not associated with within‐twin‐pair differences in most adolescent outcomes after accounting for shared familial liability, suggesting that earlier pubertal timing and adolescent outcomes both reflect familial risk factors. Biometric models indicated that associations between earlier pubertal timing and negative adolescent outcomes were largely attributable to shared genetic liability. Conclusions: Although earlier pubertal timing was associated with negative adolescent outcomes, our results suggests that these associations did not appear to be caused by earlier pubertal timing but were likely caused by shared genetic influences. [ABSTRACT FROM AUTHOR]
Copyright of Journal of Child Psychology & Psychiatry is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Pubertal timing and adolescent outcomes: investigating explanations for associations with a genetically informed design.
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  Data: <searchLink fieldCode="AR" term="%22Padrutt%2C+Emily+R%2E%22">Padrutt, Emily R.</searchLink><br /><searchLink fieldCode="AR" term="%22Harper%2C+Jeremy%22">Harper, Jeremy</searchLink><br /><searchLink fieldCode="AR" term="%22Schaefer%2C+Jonathan+D%2E%22">Schaefer, Jonathan D.</searchLink><br /><searchLink fieldCode="AR" term="%22Nelson%2C+Kayla+M%2E%22">Nelson, Kayla M.</searchLink><br /><searchLink fieldCode="AR" term="%22McGue%2C+Matt%22">McGue, Matt</searchLink><br /><searchLink fieldCode="AR" term="%22Iacono%2C+William+G%2E%22">Iacono, William G.</searchLink><br /><searchLink fieldCode="AR" term="%22Wilson%2C+Sylia%22">Wilson, Sylia</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22Journal+of+Child+Psychology+%26+Psychiatry%22">Journal of Child Psychology & Psychiatry</searchLink>. Aug2023, Vol. 64 Issue 8, p1232-1241. 10p. 2 Charts, 2 Graphs.
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  Data: <searchLink fieldCode="DE" term="%22Risk-taking+behavior%22">Risk-taking behavior</searchLink><br /><searchLink fieldCode="DE" term="%22Evaluation+of+medical+care%22">Evaluation of medical care</searchLink><br /><searchLink fieldCode="DE" term="%22Genetics%22">Genetics</searchLink><br /><searchLink fieldCode="DE" term="%22Substance+abuse%22">Substance abuse</searchLink><br /><searchLink fieldCode="DE" term="%22Time%22">Time</searchLink><br /><searchLink fieldCode="DE" term="%22Age+distribution%22">Age distribution</searchLink><br /><searchLink fieldCode="DE" term="%22Puberty%22">Puberty</searchLink><br /><searchLink fieldCode="DE" term="%22Descriptive+statistics%22">Descriptive statistics</searchLink><br /><searchLink fieldCode="DE" term="%22Research+funding%22">Research funding</searchLink><br /><searchLink fieldCode="DE" term="%22Biometry%22">Biometry</searchLink><br /><searchLink fieldCode="DE" term="%22Adolescence%22">Adolescence</searchLink>
– Name: Abstract
  Label: Abstract
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  Data: Background: Psychopathology and risky behaviors increase during adolescence, and understanding which adolescents are most at risk informs prevention and intervention efforts. Pubertal timing relative to same‐sex, same‐age peers is a known correlate of adolescent outcomes among both boys and girls. However, it remains unclear whether this relation is better explained by a plausible causal process or unobserved familial liability. Methods: We extended previous research by examining associations between pubertal timing in early adolescence (age 14) and outcomes in later adolescence (age 17) in a community sample of 2,510 twins (49% boys, 51% girls). Results: Earlier pubertal timing was associated with more substance use, risk behavior, internalizing and externalizing problems, and peer problems in later adolescence; these effects were small, consistent with previous literature. Follow‐up co‐twin control analyses indicated that within‐twin‐pair differences in pubertal timing were not associated with within‐twin‐pair differences in most adolescent outcomes after accounting for shared familial liability, suggesting that earlier pubertal timing and adolescent outcomes both reflect familial risk factors. Biometric models indicated that associations between earlier pubertal timing and negative adolescent outcomes were largely attributable to shared genetic liability. Conclusions: Although earlier pubertal timing was associated with negative adolescent outcomes, our results suggests that these associations did not appear to be caused by earlier pubertal timing but were likely caused by shared genetic influences. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Journal of Child Psychology & Psychiatry is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1111/jcpp.13808
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      – Code: eng
        Text: English
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      Pagination:
        PageCount: 10
        StartPage: 1232
    Subjects:
      – SubjectFull: Risk-taking behavior
        Type: general
      – SubjectFull: Evaluation of medical care
        Type: general
      – SubjectFull: Genetics
        Type: general
      – SubjectFull: Substance abuse
        Type: general
      – SubjectFull: Time
        Type: general
      – SubjectFull: Age distribution
        Type: general
      – SubjectFull: Puberty
        Type: general
      – SubjectFull: Descriptive statistics
        Type: general
      – SubjectFull: Research funding
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      – SubjectFull: Biometry
        Type: general
      – SubjectFull: Adolescence
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      – TitleFull: Pubertal timing and adolescent outcomes: investigating explanations for associations with a genetically informed design.
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            NameFull: Padrutt, Emily R.
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            NameFull: Harper, Jeremy
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              M: 08
              Text: Aug2023
              Type: published
              Y: 2023
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