Italian Huntington disease patients--data and tissue bank.

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Bibliographic Details
Title:	Italian Huntington disease patients--data and tissue bank.
Authors:	Squitieri, F., Cannella, M., Gaudio, L., Martino, T., Maglione, V., Giallonardo, P., Simonelli, M., Simonelli, G., Mangeruga, D., Ciarmiello, A., Pierelli, F.
Source:	Neurological Sciences. Oct2003, Vol. 24 Issue 3, p215-216. 2p.
Subjects:	Huntington disease, Tissue banks, Tissues, Health facilities, Neurogenetics, Cell culture, Cell lines, Medical records, Bioethics, Age factors in disease, Comparative studies, DNA, Family health, Magnetic resonance imaging, Research methodology, Medical cooperation, Genetic mutation, Research, Research funding, Positron emission tomography, Evaluation research, Sequence analysis
Geographic Terms:	Italy
Abstract:	We have collected clinical and genetic data on Huntington disease (HD) patients and their families over the last 5 years at the Unit of Neurogenetics, IRCCS Neuromed of Pozzilli (IS), Italy. Data on 854 mutation carriers are included in the data bank, together with a large number of DNA samples, blood, and other tissues. In particular, lymphoblastoid cell lines from 100 patients, including subjects carrying very rare genetic conditions (CAG mutation homozygosity, juvenile and infantile onset, pre-mutations) have been established. For all these initiatives ethical approval from the bioethics committee was obtained. We wish to extend this initiative to all families, investigators, and institutions within and, possibly outside, the Italian border in an attempt to enlarge the bank and to institute a HD Research Roster. [ABSTRACT FROM AUTHOR]
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Database:	Psychology and Behavioral Sciences Collection

Description
Abstract:	We have collected clinical and genetic data on Huntington disease (HD) patients and their families over the last 5 years at the Unit of Neurogenetics, IRCCS Neuromed of Pozzilli (IS), Italy. Data on 854 mutation carriers are included in the data bank, together with a large number of DNA samples, blood, and other tissues. In particular, lymphoblastoid cell lines from 100 patients, including subjects carrying very rare genetic conditions (CAG mutation homozygosity, juvenile and infantile onset, pre-mutations) have been established. For all these initiatives ethical approval from the bioethics committee was obtained. We wish to extend this initiative to all families, investigators, and institutions within and, possibly outside, the Italian border in an attempt to enlarge the bank and to institute a HD Research Roster. [ABSTRACT FROM AUTHOR]
ISSN:	15901874
DOI:	10.1007/s10072-003-0137-8