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Health utilities and willingness to pay in adult patients with coeliac disease in Hungary.

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Title: Health utilities and willingness to pay in adult patients with coeliac disease in Hungary.
Authors: Angyal, M. Mercédesz (AUTHOR), Lakatos, Peter L. (AUTHOR), Jenei, Balázs (AUTHOR), Brodszky, Valentin (AUTHOR), Rencz, Fanni (AUTHOR)
Source: Quality of Life Research. Sep2023, Vol. 32 Issue 9, p2503-2516. 14p. 1 Diagram, 5 Charts, 1 Graph.
Subjects: Celiac disease, Willingness to pay, Gluten-free foods, Cost benefit analysis, Quality of life, Gluten-free diet
Geographic Terms: Hungary
Abstract: Background: Coeliac disease (CD) is a life-long food-related disorder with a global prevalence of approximately 1%. Patients with CD often experience reduced health-related quality of life that could improve with a strict adherence to a gluten-free diet (GFD). Objectives: To obtain visual analogue scale (VAS), time trade-off (TTO) and willingness-to-pay (WTP) values amongst patients with CD. Methods: In 2020–2021, a cross-sectional online survey was conducted amongst 312 adult CD patients in Hungary. Patients completed the Gastrointestinal Symptom Rating Scale (GSRS) and evaluated their current health and three hypothetical health state vignettes defined based on dietary adherence using VAS, conventional 10-year TTO and WTP. Multivariate regressions were used to explore the effect of patients' demographic and clinical characteristics on utility and WTP values. Results: Mean VAS values for current health and 'CD with strict adherence to GFD', 'CD with loose adherence to GFD' and 'CD without GFD' hypothetical health states were 79.69 ± 18.52, 85.36 ± 16.18, 62.44 ± 19.91 and 36.69 ± 25.83, respectively. Corresponding mean TTO utilities were: 0.90 ± 0.19, 0.91 ± 0.20, 0.87 ± 0.23 and 0.76 ± 0.29. Mean annual WTP values for returning to full health were: €845 ± 1077, €648 ± 1002, €862 ± 1135 and €1251 ± 1496. Older age at diagnosis, male sex, more severe gastrointestinal symptoms (GSRS) and having comorbidities were associated with lower VAS and TTO or higher WTP values for current own health (p < 0.05). Conclusion: This is the first study to report TTO utilities for CD health states. Strict adherence to the GFD may result in substantial health gains in symptomatic patients. Utilities and WTP results can be used to estimate benefits of GFD in cost-utility and cost–benefit analyses. [ABSTRACT FROM AUTHOR]
Copyright of Quality of Life Research is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Health utilities and willingness to pay in adult patients with coeliac disease in Hungary.
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  Data: &lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Angyal%2C+M%2E+Merc&#233;desz%22&quot;&gt;Angyal, M. Merc&#233;desz&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Lakatos%2C+Peter+L%2E%22&quot;&gt;Lakatos, Peter L.&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Jenei%2C+Bal&#225;zs%22&quot;&gt;Jenei, Bal&#225;zs&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Brodszky%2C+Valentin%22&quot;&gt;Brodszky, Valentin&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Rencz%2C+Fanni%22&quot;&gt;Rencz, Fanni&lt;/searchLink&gt; (AUTHOR)
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  Data: &lt;searchLink fieldCode=&quot;JN&quot; term=&quot;%22Quality+of+Life+Research%22&quot;&gt;Quality of Life Research&lt;/searchLink&gt;. Sep2023, Vol. 32 Issue 9, p2503-2516. 14p. 1 Diagram, 5 Charts, 1 Graph.
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  Data: &lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Celiac+disease%22&quot;&gt;Celiac disease&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Willingness+to+pay%22&quot;&gt;Willingness to pay&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Gluten-free+foods%22&quot;&gt;Gluten-free foods&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Cost+benefit+analysis%22&quot;&gt;Cost benefit analysis&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Quality+of+life%22&quot;&gt;Quality of life&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Gluten-free+diet%22&quot;&gt;Gluten-free diet&lt;/searchLink&gt;
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  Data: &lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Hungary%22&quot;&gt;Hungary&lt;/searchLink&gt;
– Name: Abstract
  Label: Abstract
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  Data: Background: Coeliac disease (CD) is a life-long food-related disorder with a global prevalence of approximately 1%. Patients with CD often experience reduced health-related quality of life that could improve with a strict adherence to a gluten-free diet (GFD). Objectives: To obtain visual analogue scale (VAS), time trade-off (TTO) and willingness-to-pay (WTP) values amongst patients with CD. Methods: In 2020–2021, a cross-sectional online survey was conducted amongst 312 adult CD patients in Hungary. Patients completed the Gastrointestinal Symptom Rating Scale (GSRS) and evaluated their current health and three hypothetical health state vignettes defined based on dietary adherence using VAS, conventional 10-year TTO and WTP. Multivariate regressions were used to explore the effect of patients&#39; demographic and clinical characteristics on utility and WTP values. Results: Mean VAS values for current health and &#39;CD with strict adherence to GFD&#39;, &#39;CD with loose adherence to GFD&#39; and &#39;CD without GFD&#39; hypothetical health states were 79.69 &#177; 18.52, 85.36 &#177; 16.18, 62.44 &#177; 19.91 and 36.69 &#177; 25.83, respectively. Corresponding mean TTO utilities were: 0.90 &#177; 0.19, 0.91 &#177; 0.20, 0.87 &#177; 0.23 and 0.76 &#177; 0.29. Mean annual WTP values for returning to full health were: €845 &#177; 1077, €648 &#177; 1002, €862 &#177; 1135 and €1251 &#177; 1496. Older age at diagnosis, male sex, more severe gastrointestinal symptoms (GSRS) and having comorbidities were associated with lower VAS and TTO or higher WTP values for current own health (p &lt; 0.05). Conclusion: This is the first study to report TTO utilities for CD health states. Strict adherence to the GFD may result in substantial health gains in symptomatic patients. Utilities and WTP results can be used to estimate benefits of GFD in cost-utility and cost–benefit analyses. [ABSTRACT FROM AUTHOR]
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  Data: &lt;i&gt;Copyright of Quality of Life Research is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
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      – Type: doi
        Value: 10.1007/s11136-023-03418-w
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      – Code: eng
        Text: English
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        PageCount: 14
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    Subjects:
      – SubjectFull: Celiac disease
        Type: general
      – SubjectFull: Willingness to pay
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      – SubjectFull: Gluten-free foods
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      – SubjectFull: Gluten-free diet
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      – SubjectFull: Hungary
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              M: 09
              Text: Sep2023
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