View in EDS HTML Full Text PDF Full Text

The relationship between genetic liability, childhood maltreatment, and IQ: findings from the EU-GEI multicentric case–control study.

Saved in:
Bibliographic Details
Title: The relationship between genetic liability, childhood maltreatment, and IQ: findings from the EU-GEI multicentric case–control study.
Authors: Sideli, Lucia (AUTHOR), Aas, Monica (AUTHOR), Quattrone, Diego (AUTHOR), La Barbera, Daniele (AUTHOR), La Cascia, Caterina (AUTHOR), Ferraro, Laura (AUTHOR), Alameda, Luis (AUTHOR), Velthorst, Eva (AUTHOR), Trotta, Giulia (AUTHOR), Tripoli, Giada (AUTHOR), Schimmenti, Adriano (AUTHOR), Fontana, Andrea (AUTHOR), Gayer-Anderson, Charlotte (AUTHOR), Stilo, Simona (AUTHOR), Seminerio, Fabio (AUTHOR), Sartorio, Crocettarachele (AUTHOR), Marrazzo, Giovanna (AUTHOR), Lasalvia, Antonio (AUTHOR), Tosato, Sarah (AUTHOR), Tarricone, Ilaria (AUTHOR)
Source: Social Psychiatry & Psychiatric Epidemiology. Oct2023, Vol. 58 Issue 10, p1573-1580. 8p.
Subjects: Child abuse, Disease risk factors, Monogenic & polygenic inheritance (Genetics), Intelligence levels, Gene expression
Abstract: This study investigated if the association between childhood maltreatment and cognition among psychosis patients and community controls was partially accounted for by genetic liability for psychosis. Patients with first-episode psychosis (N = 755) and unaffected controls (N = 1219) from the EU-GEI study were assessed for childhood maltreatment, intelligence quotient (IQ), family history of psychosis (FH), and polygenic risk score for schizophrenia (SZ-PRS). Controlling for FH and SZ-PRS did not attenuate the association between childhood maltreatment and IQ in cases or controls. Findings suggest that these expressions of genetic liability cannot account for the lower levels of cognition found among adults maltreated in childhood. [ABSTRACT FROM AUTHOR]
Copyright of Social Psychiatry & Psychiatric Epidemiology is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: pbh
DbLabel: Psychology and Behavioral Sciences Collection
An: 170717469
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: The relationship between genetic liability, childhood maltreatment, and IQ: findings from the EU-GEI multicentric case–control study.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Sideli%2C+Lucia%22">Sideli, Lucia</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Aas%2C+Monica%22">Aas, Monica</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Quattrone%2C+Diego%22">Quattrone, Diego</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22La+Barbera%2C+Daniele%22">La Barbera, Daniele</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22La+Cascia%2C+Caterina%22">La Cascia, Caterina</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Ferraro%2C+Laura%22">Ferraro, Laura</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Alameda%2C+Luis%22">Alameda, Luis</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Velthorst%2C+Eva%22">Velthorst, Eva</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Trotta%2C+Giulia%22">Trotta, Giulia</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Tripoli%2C+Giada%22">Tripoli, Giada</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Schimmenti%2C+Adriano%22">Schimmenti, Adriano</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Fontana%2C+Andrea%22">Fontana, Andrea</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Gayer-Anderson%2C+Charlotte%22">Gayer-Anderson, Charlotte</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Stilo%2C+Simona%22">Stilo, Simona</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Seminerio%2C+Fabio%22">Seminerio, Fabio</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Sartorio%2C+Crocettarachele%22">Sartorio, Crocettarachele</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Marrazzo%2C+Giovanna%22">Marrazzo, Giovanna</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Lasalvia%2C+Antonio%22">Lasalvia, Antonio</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Tosato%2C+Sarah%22">Tosato, Sarah</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Tarricone%2C+Ilaria%22">Tarricone, Ilaria</searchLink> (AUTHOR)
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22Social+Psychiatry+%26+Psychiatric+Epidemiology%22">Social Psychiatry & Psychiatric Epidemiology</searchLink>. Oct2023, Vol. 58 Issue 10, p1573-1580. 8p.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Child+abuse%22">Child abuse</searchLink><br /><searchLink fieldCode="DE" term="%22Disease+risk+factors%22">Disease risk factors</searchLink><br /><searchLink fieldCode="DE" term="%22Monogenic+%26+polygenic+inheritance+%28Genetics%29%22">Monogenic & polygenic inheritance (Genetics)</searchLink><br /><searchLink fieldCode="DE" term="%22Intelligence+levels%22">Intelligence levels</searchLink><br /><searchLink fieldCode="DE" term="%22Gene+expression%22">Gene expression</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: This study investigated if the association between childhood maltreatment and cognition among psychosis patients and community controls was partially accounted for by genetic liability for psychosis. Patients with first-episode psychosis (N = 755) and unaffected controls (N = 1219) from the EU-GEI study were assessed for childhood maltreatment, intelligence quotient (IQ), family history of psychosis (FH), and polygenic risk score for schizophrenia (SZ-PRS). Controlling for FH and SZ-PRS did not attenuate the association between childhood maltreatment and IQ in cases or controls. Findings suggest that these expressions of genetic liability cannot account for the lower levels of cognition found among adults maltreated in childhood. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Social Psychiatry & Psychiatric Epidemiology is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=170717469
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1007/s00127-023-02513-0
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 8
        StartPage: 1573
    Subjects:
      – SubjectFull: Child abuse
        Type: general
      – SubjectFull: Disease risk factors
        Type: general
      – SubjectFull: Monogenic & polygenic inheritance (Genetics)
        Type: general
      – SubjectFull: Intelligence levels
        Type: general
      – SubjectFull: Gene expression
        Type: general
    Titles:
      – TitleFull: The relationship between genetic liability, childhood maltreatment, and IQ: findings from the EU-GEI multicentric case–control study.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Sideli, Lucia
      – PersonEntity:
          Name:
            NameFull: Aas, Monica
      – PersonEntity:
          Name:
            NameFull: Quattrone, Diego
      – PersonEntity:
          Name:
            NameFull: La Barbera, Daniele
      – PersonEntity:
          Name:
            NameFull: La Cascia, Caterina
      – PersonEntity:
          Name:
            NameFull: Ferraro, Laura
      – PersonEntity:
          Name:
            NameFull: Alameda, Luis
      – PersonEntity:
          Name:
            NameFull: Velthorst, Eva
      – PersonEntity:
          Name:
            NameFull: Trotta, Giulia
      – PersonEntity:
          Name:
            NameFull: Tripoli, Giada
      – PersonEntity:
          Name:
            NameFull: Schimmenti, Adriano
      – PersonEntity:
          Name:
            NameFull: Fontana, Andrea
      – PersonEntity:
          Name:
            NameFull: Gayer-Anderson, Charlotte
      – PersonEntity:
          Name:
            NameFull: Stilo, Simona
      – PersonEntity:
          Name:
            NameFull: Seminerio, Fabio
      – PersonEntity:
          Name:
            NameFull: Sartorio, Crocettarachele
      – PersonEntity:
          Name:
            NameFull: Marrazzo, Giovanna
      – PersonEntity:
          Name:
            NameFull: Lasalvia, Antonio
      – PersonEntity:
          Name:
            NameFull: Tosato, Sarah
      – PersonEntity:
          Name:
            NameFull: Tarricone, Ilaria
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 10
              Text: Oct2023
              Type: published
              Y: 2023
          Identifiers:
            – Type: issn-print
              Value: 09337954
          Numbering:
            – Type: volume
              Value: 58
            – Type: issue
              Value: 10
          Titles:
            – TitleFull: Social Psychiatry & Psychiatric Epidemiology
              Type: main
ResultId 1