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Multiple cranial neuropathy due to varicella zoster virus reactivation without vesicular rash: a challenging diagnosis.

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Title: Multiple cranial neuropathy due to varicella zoster virus reactivation without vesicular rash: a challenging diagnosis.
Authors: Stornaiuolo, Antonio (AUTHOR), Iodice, Rosa (AUTHOR), De Simone, Roberto (AUTHOR), Russo, Cinzia (AUTHOR), Rubino, Marica (AUTHOR), Braca, Simone (AUTHOR), Miele, Angelo (AUTHOR), Tozza, Stefano (AUTHOR), Nolano, Maria (AUTHOR), Manganelli, Fiore (AUTHOR)
Source: Neurological Sciences. Oct2023, Vol. 44 Issue 10, p3687-3689. 3p.
Subjects: Varicella-zoster virus, Virus reactivation, Cranial nerves, Facial nerve, Neuropathy, Herpes zoster, Facial paralysis
Abstract: Ramsay Hunt syndrome is due to reactivation of varicella zoster virus (VZV) dormant in the geniculate ganglion of the facial nerve. The diagnosis is typically based on clinical triad of ipsilateral facial paralysis, otalgia, and vesicles in the auditory canal or the auricle. However, Ramsay Hunt syndrome may occur without skin eruption in up to one third of patients. Moreover, the involvement of other cranial nerves in addition to the facial nerve has been also reported. Herein, we reported a case report of a man who developed a multiple cranial neuropathy caused by VZV reactivation without skin vesicular eruption. The present case underlines a possible diagnostic challenge that clinicians may hit when facing a common disorder such as peripheral facial palsy. Indeed, clinicians must be aware that Ramsay Hunt syndrome may develop without skin vesicular eruption as well it may be complicated by multiple cranial nerve involvement. Antiviral therapy is effective in VZV reactivation for recovery of nerve function. [ABSTRACT FROM AUTHOR]
Copyright of Neurological Sciences is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Multiple cranial neuropathy due to varicella zoster virus reactivation without vesicular rash: a challenging diagnosis.
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  Data: <searchLink fieldCode="JN" term="%22Neurological+Sciences%22">Neurological Sciences</searchLink>. Oct2023, Vol. 44 Issue 10, p3687-3689. 3p.
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  Data: <searchLink fieldCode="DE" term="%22Varicella-zoster+virus%22">Varicella-zoster virus</searchLink><br /><searchLink fieldCode="DE" term="%22Virus+reactivation%22">Virus reactivation</searchLink><br /><searchLink fieldCode="DE" term="%22Cranial+nerves%22">Cranial nerves</searchLink><br /><searchLink fieldCode="DE" term="%22Facial+nerve%22">Facial nerve</searchLink><br /><searchLink fieldCode="DE" term="%22Neuropathy%22">Neuropathy</searchLink><br /><searchLink fieldCode="DE" term="%22Herpes+zoster%22">Herpes zoster</searchLink><br /><searchLink fieldCode="DE" term="%22Facial+paralysis%22">Facial paralysis</searchLink>
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  Data: Ramsay Hunt syndrome is due to reactivation of varicella zoster virus (VZV) dormant in the geniculate ganglion of the facial nerve. The diagnosis is typically based on clinical triad of ipsilateral facial paralysis, otalgia, and vesicles in the auditory canal or the auricle. However, Ramsay Hunt syndrome may occur without skin eruption in up to one third of patients. Moreover, the involvement of other cranial nerves in addition to the facial nerve has been also reported. Herein, we reported a case report of a man who developed a multiple cranial neuropathy caused by VZV reactivation without skin vesicular eruption. The present case underlines a possible diagnostic challenge that clinicians may hit when facing a common disorder such as peripheral facial palsy. Indeed, clinicians must be aware that Ramsay Hunt syndrome may develop without skin vesicular eruption as well it may be complicated by multiple cranial nerve involvement. Antiviral therapy is effective in VZV reactivation for recovery of nerve function. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Neurological Sciences is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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      – SubjectFull: Facial paralysis
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              Text: Oct2023
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