View in EDS HTML Full Text PDF Full Text

Subgenual Anterior Cingulate Cortex Reactivity to Rejection Vs. Acceptance Predicts Depressive Symptoms among Adolescents with an Anxiety History.

Saved in:
Bibliographic Details
Title: Subgenual Anterior Cingulate Cortex Reactivity to Rejection Vs. Acceptance Predicts Depressive Symptoms among Adolescents with an Anxiety History.
Authors: Silk, Jennifer S. (AUTHOR), Sequeira, Stefanie S. (AUTHOR), Jones, Neil P. (AUTHOR), Lee, Kyung Hwa (AUTHOR), Dahl, Ronald E. (AUTHOR), Forbes, Erika. E. (AUTHOR), Ryan, Neal D. (AUTHOR), Ladouceur, Cecile D. (AUTHOR)
Source: Journal of Clinical Child & Adolescent Psychology. Sep/Oct2023, Vol. 52 Issue 5, p659-674. 16p.
Subjects: Mental depression, Cingulate cortex, Social anxiety, Ecological momentary assessments (Clinical psychology), Anxiety, Teenagers
Abstract: The goal of this study was to examine whether neural sensitivity to negative peer evaluation conveys risk for depression among youth with a history of anxiety. We hypothesized that brain activation in regions that process affective salience in response to rejection, relative to acceptance, from virtual peers would predict depressive symptoms 1 year later and would be associated with ecological momentary assessment (EMA) reports of peer connectedness. Participants were 38 adolescents ages 11–16 (50% female) with a history of anxiety, recruited from a previous clinical trial. The study was a prospective naturalistic follow-up of depressive symptoms assessed 2 years (Wave 2) and 3 years (Wave 3) following treatment. At Wave 2, participants completed the Chatroom Interact Task during neuroimaging and 16 days of EMA. Controlling for depressive and anxiety symptoms at Wave 2, subgenual anterior cingulate (sgACC; β =.39, p =.010) activation to peer rejection (vs. acceptance) predicted depressive symptoms at Wave 3. SgACC activation to rejection (vs. acceptance) was highly negatively correlated with EMA reports of connectedness with peers in daily life (r = –.71, p <.001). Findings suggest that elevated sgACC activation to negative, relative to positive, peer evaluation may serve as a risk factor for depressive symptoms among youth with a history of anxiety, perhaps by promoting vigilance or reactivity to social evaluative threats. SgACC activation to simulated peer evaluation appears to have implications for understanding how adolescents experience their daily social environments in ways that could contribute to depressive symptoms. [ABSTRACT FROM AUTHOR]
Copyright of Journal of Clinical Child & Adolescent Psychology is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: pbh
DbLabel: Psychology and Behavioral Sciences Collection
An: 171995934
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Subgenual Anterior Cingulate Cortex Reactivity to Rejection Vs. Acceptance Predicts Depressive Symptoms among Adolescents with an Anxiety History.
– Name: Author
  Label: Authors
  Group: Au
  Data: &lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Silk%2C+Jennifer+S%2E%22&quot;&gt;Silk, Jennifer S.&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Sequeira%2C+Stefanie+S%2E%22&quot;&gt;Sequeira, Stefanie S.&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Jones%2C+Neil+P%2E%22&quot;&gt;Jones, Neil P.&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Lee%2C+Kyung+Hwa%22&quot;&gt;Lee, Kyung Hwa&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Dahl%2C+Ronald+E%2E%22&quot;&gt;Dahl, Ronald E.&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Forbes%2C+Erika%2E+E%2E%22&quot;&gt;Forbes, Erika. E.&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Ryan%2C+Neal+D%2E%22&quot;&gt;Ryan, Neal D.&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Ladouceur%2C+Cecile+D%2E%22&quot;&gt;Ladouceur, Cecile D.&lt;/searchLink&gt; (AUTHOR)
– Name: TitleSource
  Label: Source
  Group: Src
  Data: &lt;searchLink fieldCode=&quot;JN&quot; term=&quot;%22Journal+of+Clinical+Child+%26+Adolescent+Psychology%22&quot;&gt;Journal of Clinical Child &amp; Adolescent Psychology&lt;/searchLink&gt;. Sep/Oct2023, Vol. 52 Issue 5, p659-674. 16p.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: &lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Mental+depression%22&quot;&gt;Mental depression&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Cingulate+cortex%22&quot;&gt;Cingulate cortex&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Social+anxiety%22&quot;&gt;Social anxiety&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Ecological+momentary+assessments+%28Clinical+psychology%29%22&quot;&gt;Ecological momentary assessments (Clinical psychology)&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Anxiety%22&quot;&gt;Anxiety&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Teenagers%22&quot;&gt;Teenagers&lt;/searchLink&gt;
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: The goal of this study was to examine whether neural sensitivity to negative peer evaluation conveys risk for depression among youth with a history of anxiety. We hypothesized that brain activation in regions that process affective salience in response to rejection, relative to acceptance, from virtual peers would predict depressive symptoms 1 year later and would be associated with ecological momentary assessment (EMA) reports of peer connectedness. Participants were 38 adolescents ages 11–16 (50% female) with a history of anxiety, recruited from a previous clinical trial. The study was a prospective naturalistic follow-up of depressive symptoms assessed 2 years (Wave 2) and 3 years (Wave 3) following treatment. At Wave 2, participants completed the Chatroom Interact Task during neuroimaging and 16 days of EMA. Controlling for depressive and anxiety symptoms at Wave 2, subgenual anterior cingulate (sgACC; β =.39, p =.010) activation to peer rejection (vs. acceptance) predicted depressive symptoms at Wave 3. SgACC activation to rejection (vs. acceptance) was highly negatively correlated with EMA reports of connectedness with peers in daily life (r = –.71, p &lt;.001). Findings suggest that elevated sgACC activation to negative, relative to positive, peer evaluation may serve as a risk factor for depressive symptoms among youth with a history of anxiety, perhaps by promoting vigilance or reactivity to social evaluative threats. SgACC activation to simulated peer evaluation appears to have implications for understanding how adolescents experience their daily social environments in ways that could contribute to depressive symptoms. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: &lt;i&gt;Copyright of Journal of Clinical Child &amp; Adolescent Psychology is the property of Taylor &amp; Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=171995934
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1080/15374416.2021.2019048
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 16
        StartPage: 659
    Subjects:
      – SubjectFull: Mental depression
        Type: general
      – SubjectFull: Cingulate cortex
        Type: general
      – SubjectFull: Social anxiety
        Type: general
      – SubjectFull: Ecological momentary assessments (Clinical psychology)
        Type: general
      – SubjectFull: Anxiety
        Type: general
      – SubjectFull: Teenagers
        Type: general
    Titles:
      – TitleFull: Subgenual Anterior Cingulate Cortex Reactivity to Rejection Vs. Acceptance Predicts Depressive Symptoms among Adolescents with an Anxiety History.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Silk, Jennifer S.
      – PersonEntity:
          Name:
            NameFull: Sequeira, Stefanie S.
      – PersonEntity:
          Name:
            NameFull: Jones, Neil P.
      – PersonEntity:
          Name:
            NameFull: Lee, Kyung Hwa
      – PersonEntity:
          Name:
            NameFull: Dahl, Ronald E.
      – PersonEntity:
          Name:
            NameFull: Forbes, Erika. E.
      – PersonEntity:
          Name:
            NameFull: Ryan, Neal D.
      – PersonEntity:
          Name:
            NameFull: Ladouceur, Cecile D.
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 09
              Text: Sep/Oct2023
              Type: published
              Y: 2023
          Identifiers:
            – Type: issn-print
              Value: 15374416
          Numbering:
            – Type: volume
              Value: 52
            – Type: issue
              Value: 5
          Titles:
            – TitleFull: Journal of Clinical Child & Adolescent Psychology
              Type: main
ResultId 1