Outcomes of electroconvulsive therapy in patients with depressive symptoms with versus without comorbid personality disorders/traits: A systematic review and meta‐analysis.
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| Title: | Outcomes of electroconvulsive therapy in patients with depressive symptoms with versus without comorbid personality disorders/traits: A systematic review and meta‐analysis. |
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| Authors: | Ferrea, Stefano (AUTHOR), Petrides, Georgios (AUTHOR), Ehrt‐Schäfer, Yamina (AUTHOR), Angst, Jules (AUTHOR), Seifritz, Erich (AUTHOR), Olbrich, Sebastian (AUTHOR), Schoretsanitis, Georgios (AUTHOR) |
| Source: | Acta Psychiatrica Scandinavica. Jan2024, Vol. 149 Issue 1, p18-32. 15p. |
| Subjects: | Personality disorders, Electroconvulsive therapy, Mental depression, Comorbidity, Stimulus & response (Psychology) |
| Abstract: | Aims: To assess electroconvulsive therapy (ECT) outcomes in patients affected by depressive symptoms with versus without additional comorbid personality disorders/traits. Methods: We identified observational studies investigating ECT clinical outcomes in patients affected by depressive symptoms with versus without comorbid personality disorders/traits in Embase/Medline in 11/2022. Our protocol was registered with PROSPERO (CRD42023390833). Study quality was evaluated using the Newcastle‐Ottawa‐Scale. Our primary outcomes were ECT response and remission rates. Meta‐regression analyses included effects of in/outpatient percentages, age, number of ECT sessions, and electrode placement; subgroup analyses included the assessment methods for personality disorders/traits. We performed sensitivity analyses after excluding poor‐quality studies. Results: A total of 20 studies (n = 11,390) were included in our analysis. Patients with comorbid personality disorders/traits had lower remission rates (OR = 0.42, 95% CI = 0.31, 0.58, p < 0.001) with substantial heterogeneity (I2 = 93.0%) as well as lower response rates (OR = 0.35, 95% CI = 0.24, 0.51, n = 5129, p < 0.001) with substantial heterogeneity (I2 = 93.0%) compared with patients without comorbid personality disorders/traits. Relapse rates were higher in patients with versus without comorbid personality disorders/traits (OR = 3.23, 95% CI = 1.40, 7.45, k = 4, n = 239, p = 0.006) with moderate heterogeneity (I2 = 75.0%) and post‐ECT memory impairment was more frequent in patients with versus without comorbid personality disorders/traits (OR = 1.41, 95% CI = 1.36, 1.46, k = 4, n = 471, p < 0.001) with minimal heterogeneity (I2 = 0.0%). Dropout rates were higher in patients with versus without comorbid personality disorders/traits (OR = 1.58, 95% CI = 1.13, 2.21, k = 3, n = 6145, p = 0.008). Conclusions: Patients with comorbid personality disorders/traits treated with ECT are reported to have lower response and remission rates and higher rates of side effects and relapse rates compared with patients without personality disorders/traits. [ABSTRACT FROM AUTHOR] |
| Copyright of Acta Psychiatrica Scandinavica is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 174180957 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Outcomes of electroconvulsive therapy in patients with depressive symptoms with versus without comorbid personality disorders/traits: A systematic review and meta‐analysis. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Ferrea%2C+Stefano%22">Ferrea, Stefano</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Petrides%2C+Georgios%22">Petrides, Georgios</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Ehrt‐Schäfer%2C+Yamina%22">Ehrt‐Schäfer, Yamina</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Angst%2C+Jules%22">Angst, Jules</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Seifritz%2C+Erich%22">Seifritz, Erich</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Olbrich%2C+Sebastian%22">Olbrich, Sebastian</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Schoretsanitis%2C+Georgios%22">Schoretsanitis, Georgios</searchLink> (AUTHOR) – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Acta+Psychiatrica+Scandinavica%22">Acta Psychiatrica Scandinavica</searchLink>. Jan2024, Vol. 149 Issue 1, p18-32. 15p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Personality+disorders%22">Personality disorders</searchLink><br /><searchLink fieldCode="DE" term="%22Electroconvulsive+therapy%22">Electroconvulsive therapy</searchLink><br /><searchLink fieldCode="DE" term="%22Mental+depression%22">Mental depression</searchLink><br /><searchLink fieldCode="DE" term="%22Comorbidity%22">Comorbidity</searchLink><br /><searchLink fieldCode="DE" term="%22Stimulus+%26+response+%28Psychology%29%22">Stimulus & response (Psychology)</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Aims: To assess electroconvulsive therapy (ECT) outcomes in patients affected by depressive symptoms with versus without additional comorbid personality disorders/traits. Methods: We identified observational studies investigating ECT clinical outcomes in patients affected by depressive symptoms with versus without comorbid personality disorders/traits in Embase/Medline in 11/2022. Our protocol was registered with PROSPERO (CRD42023390833). Study quality was evaluated using the Newcastle‐Ottawa‐Scale. Our primary outcomes were ECT response and remission rates. Meta‐regression analyses included effects of in/outpatient percentages, age, number of ECT sessions, and electrode placement; subgroup analyses included the assessment methods for personality disorders/traits. We performed sensitivity analyses after excluding poor‐quality studies. Results: A total of 20 studies (n = 11,390) were included in our analysis. Patients with comorbid personality disorders/traits had lower remission rates (OR = 0.42, 95% CI = 0.31, 0.58, p < 0.001) with substantial heterogeneity (I2 = 93.0%) as well as lower response rates (OR = 0.35, 95% CI = 0.24, 0.51, n = 5129, p < 0.001) with substantial heterogeneity (I2 = 93.0%) compared with patients without comorbid personality disorders/traits. Relapse rates were higher in patients with versus without comorbid personality disorders/traits (OR = 3.23, 95% CI = 1.40, 7.45, k = 4, n = 239, p = 0.006) with moderate heterogeneity (I2 = 75.0%) and post‐ECT memory impairment was more frequent in patients with versus without comorbid personality disorders/traits (OR = 1.41, 95% CI = 1.36, 1.46, k = 4, n = 471, p < 0.001) with minimal heterogeneity (I2 = 0.0%). Dropout rates were higher in patients with versus without comorbid personality disorders/traits (OR = 1.58, 95% CI = 1.13, 2.21, k = 3, n = 6145, p = 0.008). Conclusions: Patients with comorbid personality disorders/traits treated with ECT are reported to have lower response and remission rates and higher rates of side effects and relapse rates compared with patients without personality disorders/traits. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Acta Psychiatrica Scandinavica is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=174180957 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1111/acps.13631 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 15 StartPage: 18 Subjects: – SubjectFull: Personality disorders Type: general – SubjectFull: Electroconvulsive therapy Type: general – SubjectFull: Mental depression Type: general – SubjectFull: Comorbidity Type: general – SubjectFull: Stimulus & response (Psychology) Type: general Titles: – TitleFull: Outcomes of electroconvulsive therapy in patients with depressive symptoms with versus without comorbid personality disorders/traits: A systematic review and meta‐analysis. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Ferrea, Stefano – PersonEntity: Name: NameFull: Petrides, Georgios – PersonEntity: Name: NameFull: Ehrt‐Schäfer, Yamina – PersonEntity: Name: NameFull: Angst, Jules – PersonEntity: Name: NameFull: Seifritz, Erich – PersonEntity: Name: NameFull: Olbrich, Sebastian – PersonEntity: Name: NameFull: Schoretsanitis, Georgios IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 01 Text: Jan2024 Type: published Y: 2024 Identifiers: – Type: issn-print Value: 0001690X Numbering: – Type: volume Value: 149 – Type: issue Value: 1 Titles: – TitleFull: Acta Psychiatrica Scandinavica Type: main |
| ResultId | 1 |
