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Drug consumption rooms are effective to reduce at‐risk practices associated with HIV/HCV infections among people who inject drugs: Results from the COSINUS cohort study.

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Title: Drug consumption rooms are effective to reduce at‐risk practices associated with HIV/HCV infections among people who inject drugs: Results from the COSINUS cohort study.
Authors: Lalanne, Laurence, Roux, Perrine, Donadille, Cécile, Briand Madrid, Laelia, Célerier, Isabelle, Chauvin, Carole, Hamelin, Naomi, Kervran, Charlotte, Maradan, Gwenaëlle, Auriacombe, Marc, Jauffret‐Roustide, Marie
Source: Addiction. Jan2024, Vol. 119 Issue 1, p180-199. 20p.
Subjects: Hepatitis C risk factors, HIV infection risk factors, Risk-taking behavior, Needle sharing, Experimental design, Health services accessibility, Confidence intervals, Medical screening, Interviewing, Harm reduction, Research funding, Descriptive statistics, Repeated measures design, Opioid analgesics, Longitudinal method, Evaluation
Geographic Terms: France
Abstract: Aims: The primary aim of this study was to evaluate the impact of drug consumption rooms (DCRs) in France on injection equipment‐sharing, while the secondary aims focused upon their impact on access to hepatitis C virus (HCV) testing and opioid agonist treatment (OAT). Design: The COhort to identify Structural and INdividual factors associated with drug USe (COSINUS cohort) was a 12‐month longitudinal study of 665 people who inject drugs (PWID), conducted in Bordeaux, Marseille, Paris and Strasbourg. We used data from face‐to‐face interviews at enrolment and at 6‐month and 12‐month visits. Setting and participants: The participants were recruited in harm reduction programmes in Bordeaux and Marseille and in DCRs in Strasbourg and Paris. Participants were aged more than 18 years, French‐speaking and had injected substances the month before enrolment. Measurements We measured the impact of DCR exposure on injection equipment sharing, HCV testing and the use of medications for opioid use disorder, after adjustment for significant correlates. We used a two‐step Heckman mixed‐effects probit model, which allowed us to take into account the correlation of repeated measures and to control for potential bias due to non‐randomization between the two groups (DCR‐exposed versus DCR‐unexposed participants). Findings The difference of declared injection equipment sharing between PWID exposed to DCRs versus non‐exposed was 10% (1% for those exposed versus 11% for those non‐exposed, marginal effect = −0.10; 95% confidence interval = −0.18, −0.03); there was no impact of DCRs on HCV testing and OAT. Conclusions: In the French context, drug consumption rooms appear to have a positive impact on at‐risk practices for infectious diseases such as human immunodeficiency virus (HIV) and hepatitis C virus. [ABSTRACT FROM AUTHOR]
Copyright of Addiction is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Drug consumption rooms are effective to reduce at‐risk practices associated with HIV/HCV infections among people who inject drugs: Results from the COSINUS cohort study.
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  Data: <searchLink fieldCode="AR" term="%22Lalanne%2C+Laurence%22">Lalanne, Laurence</searchLink><br /><searchLink fieldCode="AR" term="%22Roux%2C+Perrine%22">Roux, Perrine</searchLink><br /><searchLink fieldCode="AR" term="%22Donadille%2C+Cécile%22">Donadille, Cécile</searchLink><br /><searchLink fieldCode="AR" term="%22Briand+Madrid%2C+Laelia%22">Briand Madrid, Laelia</searchLink><br /><searchLink fieldCode="AR" term="%22Célerier%2C+Isabelle%22">Célerier, Isabelle</searchLink><br /><searchLink fieldCode="AR" term="%22Chauvin%2C+Carole%22">Chauvin, Carole</searchLink><br /><searchLink fieldCode="AR" term="%22Hamelin%2C+Naomi%22">Hamelin, Naomi</searchLink><br /><searchLink fieldCode="AR" term="%22Kervran%2C+Charlotte%22">Kervran, Charlotte</searchLink><br /><searchLink fieldCode="AR" term="%22Maradan%2C+Gwenaëlle%22">Maradan, Gwenaëlle</searchLink><br /><searchLink fieldCode="AR" term="%22Auriacombe%2C+Marc%22">Auriacombe, Marc</searchLink><br /><searchLink fieldCode="AR" term="%22Jauffret‐Roustide%2C+Marie%22">Jauffret‐Roustide, Marie</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22Addiction%22">Addiction</searchLink>. Jan2024, Vol. 119 Issue 1, p180-199. 20p.
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  Data: <searchLink fieldCode="DE" term="%22Hepatitis+C+risk+factors%22">Hepatitis C risk factors</searchLink><br /><searchLink fieldCode="DE" term="%22HIV+infection+risk+factors%22">HIV infection risk factors</searchLink><br /><searchLink fieldCode="DE" term="%22Risk-taking+behavior%22">Risk-taking behavior</searchLink><br /><searchLink fieldCode="DE" term="%22Needle+sharing%22">Needle sharing</searchLink><br /><searchLink fieldCode="DE" term="%22Experimental+design%22">Experimental design</searchLink><br /><searchLink fieldCode="DE" term="%22Health+services+accessibility%22">Health services accessibility</searchLink><br /><searchLink fieldCode="DE" term="%22Confidence+intervals%22">Confidence intervals</searchLink><br /><searchLink fieldCode="DE" term="%22Medical+screening%22">Medical screening</searchLink><br /><searchLink fieldCode="DE" term="%22Interviewing%22">Interviewing</searchLink><br /><searchLink fieldCode="DE" term="%22Harm+reduction%22">Harm reduction</searchLink><br /><searchLink fieldCode="DE" term="%22Research+funding%22">Research funding</searchLink><br /><searchLink fieldCode="DE" term="%22Descriptive+statistics%22">Descriptive statistics</searchLink><br /><searchLink fieldCode="DE" term="%22Repeated+measures+design%22">Repeated measures design</searchLink><br /><searchLink fieldCode="DE" term="%22Opioid+analgesics%22">Opioid analgesics</searchLink><br /><searchLink fieldCode="DE" term="%22Longitudinal+method%22">Longitudinal method</searchLink><br /><searchLink fieldCode="DE" term="%22Evaluation%22">Evaluation</searchLink>
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  Data: <searchLink fieldCode="DE" term="%22France%22">France</searchLink>
– Name: Abstract
  Label: Abstract
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  Data: Aims: The primary aim of this study was to evaluate the impact of drug consumption rooms (DCRs) in France on injection equipment‐sharing, while the secondary aims focused upon their impact on access to hepatitis C virus (HCV) testing and opioid agonist treatment (OAT). Design: The COhort to identify Structural and INdividual factors associated with drug USe (COSINUS cohort) was a 12‐month longitudinal study of 665 people who inject drugs (PWID), conducted in Bordeaux, Marseille, Paris and Strasbourg. We used data from face‐to‐face interviews at enrolment and at 6‐month and 12‐month visits. Setting and participants: The participants were recruited in harm reduction programmes in Bordeaux and Marseille and in DCRs in Strasbourg and Paris. Participants were aged more than 18 years, French‐speaking and had injected substances the month before enrolment. Measurements We measured the impact of DCR exposure on injection equipment sharing, HCV testing and the use of medications for opioid use disorder, after adjustment for significant correlates. We used a two‐step Heckman mixed‐effects probit model, which allowed us to take into account the correlation of repeated measures and to control for potential bias due to non‐randomization between the two groups (DCR‐exposed versus DCR‐unexposed participants). Findings The difference of declared injection equipment sharing between PWID exposed to DCRs versus non‐exposed was 10% (1% for those exposed versus 11% for those non‐exposed, marginal effect = −0.10; 95% confidence interval = −0.18, −0.03); there was no impact of DCRs on HCV testing and OAT. Conclusions: In the French context, drug consumption rooms appear to have a positive impact on at‐risk practices for infectious diseases such as human immunodeficiency virus (HIV) and hepatitis C virus. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Addiction is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Value: 10.1111/add.16320
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        Text: English
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      – SubjectFull: Hepatitis C risk factors
        Type: general
      – SubjectFull: HIV infection risk factors
        Type: general
      – SubjectFull: Risk-taking behavior
        Type: general
      – SubjectFull: Needle sharing
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      – SubjectFull: Experimental design
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      – SubjectFull: Health services accessibility
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      – SubjectFull: Confidence intervals
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      – SubjectFull: Medical screening
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      – SubjectFull: Interviewing
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      – SubjectFull: Harm reduction
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      – SubjectFull: Research funding
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      – SubjectFull: Descriptive statistics
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      – SubjectFull: Repeated measures design
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      – SubjectFull: Opioid analgesics
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      – SubjectFull: Evaluation
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      – SubjectFull: France
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      – TitleFull: Drug consumption rooms are effective to reduce at‐risk practices associated with HIV/HCV infections among people who inject drugs: Results from the COSINUS cohort study.
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              Text: Jan2024
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