View in EDS HTML Full Text PDF Full Text

Early-life adversity is associated with poor iron status in infancy.

Saved in:
Bibliographic Details
Title: Early-life adversity is associated with poor iron status in infancy.
Authors: Reid, Brie M. (AUTHOR), East, Patricia (AUTHOR), Blanco, Estela (AUTHOR), Doom, Jenalee R. (AUTHOR), Burrows, Raquel A. (AUTHOR), Correa-Burrows, Paulina (AUTHOR), Lozoff, Betsy (AUTHOR), Gahagan, Sheila (AUTHOR)
Source: Development & Psychopathology. Oct2023, Vol. 35 Issue 4, p1856-1867. 12p.
Subjects: Iron in the body, Iron supplements, Infants, Iron deficiency, Life change events
Geographic Terms: Santiago (Chile)
Abstract: Exposure to early-life adversity (ELA) and iron deficiency early in life are known risk factors for suboptimal brain and socioemotional development. Iron deficiency may arise from and co-occur with ELA, which could negatively affect development. In the present study, we investigated whether ELA is associated with iron deficiency in infants receiving no iron supplementation. This study is a secondary analysis of extant data collected in the 1990s; participants were healthy infants from working-class communities in Santiago, Chile (N = 534, 45.5% female). We measured stressful life events, maternal depression, and low home support for child development during infancy and assessed iron status when the infant was 12 months old. Slightly more than half of the infants were iron-deficient (51%), and 25.8% were iron-deficient anemic at 12 months. Results indicated that ELA was associated with lower iron levels and iron deficiency at 12 months. The findings are consistent with animal and human prenatal models of stress and iron status and provide evidence of the association between postnatal ELA and iron status in humans. The findings also highlight a nutritional pathway by which ELA may impact development and present a nutritionally-focused avenue for future research on ELA and psychopathology. [ABSTRACT FROM AUTHOR]
Copyright of Development & Psychopathology is the property of Cambridge University Press and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: pbh
DbLabel: Psychology and Behavioral Sciences Collection
An: 174341656
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Early-life adversity is associated with poor iron status in infancy.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Reid%2C+Brie+M%2E%22">Reid, Brie M.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22East%2C+Patricia%22">East, Patricia</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Blanco%2C+Estela%22">Blanco, Estela</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Doom%2C+Jenalee+R%2E%22">Doom, Jenalee R.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Burrows%2C+Raquel+A%2E%22">Burrows, Raquel A.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Correa-Burrows%2C+Paulina%22">Correa-Burrows, Paulina</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Lozoff%2C+Betsy%22">Lozoff, Betsy</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Gahagan%2C+Sheila%22">Gahagan, Sheila</searchLink> (AUTHOR)
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22Development+%26+Psychopathology%22">Development & Psychopathology</searchLink>. Oct2023, Vol. 35 Issue 4, p1856-1867. 12p.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Iron+in+the+body%22">Iron in the body</searchLink><br /><searchLink fieldCode="DE" term="%22Iron+supplements%22">Iron supplements</searchLink><br /><searchLink fieldCode="DE" term="%22Infants%22">Infants</searchLink><br /><searchLink fieldCode="DE" term="%22Iron+deficiency%22">Iron deficiency</searchLink><br /><searchLink fieldCode="DE" term="%22Life+change+events%22">Life change events</searchLink>
– Name: SubjectGeographic
  Label: Geographic Terms
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Santiago+%28Chile%29%22">Santiago (Chile)</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Exposure to early-life adversity (ELA) and iron deficiency early in life are known risk factors for suboptimal brain and socioemotional development. Iron deficiency may arise from and co-occur with ELA, which could negatively affect development. In the present study, we investigated whether ELA is associated with iron deficiency in infants receiving no iron supplementation. This study is a secondary analysis of extant data collected in the 1990s; participants were healthy infants from working-class communities in Santiago, Chile (N = 534, 45.5% female). We measured stressful life events, maternal depression, and low home support for child development during infancy and assessed iron status when the infant was 12 months old. Slightly more than half of the infants were iron-deficient (51%), and 25.8% were iron-deficient anemic at 12 months. Results indicated that ELA was associated with lower iron levels and iron deficiency at 12 months. The findings are consistent with animal and human prenatal models of stress and iron status and provide evidence of the association between postnatal ELA and iron status in humans. The findings also highlight a nutritional pathway by which ELA may impact development and present a nutritionally-focused avenue for future research on ELA and psychopathology. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Development & Psychopathology is the property of Cambridge University Press and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=174341656
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1017/S0954579422000517
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 12
        StartPage: 1856
    Subjects:
      – SubjectFull: Iron in the body
        Type: general
      – SubjectFull: Iron supplements
        Type: general
      – SubjectFull: Infants
        Type: general
      – SubjectFull: Iron deficiency
        Type: general
      – SubjectFull: Life change events
        Type: general
      – SubjectFull: Santiago (Chile)
        Type: general
    Titles:
      – TitleFull: Early-life adversity is associated with poor iron status in infancy.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Reid, Brie M.
      – PersonEntity:
          Name:
            NameFull: East, Patricia
      – PersonEntity:
          Name:
            NameFull: Blanco, Estela
      – PersonEntity:
          Name:
            NameFull: Doom, Jenalee R.
      – PersonEntity:
          Name:
            NameFull: Burrows, Raquel A.
      – PersonEntity:
          Name:
            NameFull: Correa-Burrows, Paulina
      – PersonEntity:
          Name:
            NameFull: Lozoff, Betsy
      – PersonEntity:
          Name:
            NameFull: Gahagan, Sheila
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 10
              Text: Oct2023
              Type: published
              Y: 2023
          Identifiers:
            – Type: issn-print
              Value: 09545794
          Numbering:
            – Type: volume
              Value: 35
            – Type: issue
              Value: 4
          Titles:
            – TitleFull: Development & Psychopathology
              Type: main
ResultId 1