Attention and neurodevelopment in young children who are HIV-exposed uninfected.

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Title: Attention and neurodevelopment in young children who are HIV-exposed uninfected.
Authors: Young, Julia M., Chen, Vanessa, Bitnun, Ari, Read, Stanley E., Smith, Mary Lou
Source: AIDS Care. Jan2024, Vol. 36 Issue 1, p26-35. 10p.
Subjects: Education of mothers, HIV infections, Multiple regression analysis, Developmental disabilities, Neural development, Attention, Infectious disease transmission, Intellect, Employment, Research funding, Children
Abstract: Children HIV-exposed, uninfected (CHEU) are at risk for compromised developmental outcomes. Attention is important for behavioural, cognitive and academic skills, yet has not been thoroughly investigated compared to children HIV-unexposed uninfected (CHUU). Fifty-five CHEU and 51 CHUU children were recruited at 5.5 years of age. Measures of inattention (IA), hyperactivity/impulsivity (HI) and total scores were collected using the parent-reported ADHD-Rating-Scale-IV. Measures of intelligence, visuomotor skills, academics and adaptive functioning were obtained. Analyses of between-group differences were performed as were correlational and multiple regression models, accounting for maternal education, employment and delivery type. Few children met clinical cut-offs for probable ADHD (3.6% CHEU, 2.0% CHUU), and no group differences in measures of IA, HI and combined scores were found. CHEU scored significantly lower than CHUU on intelligence, visuomotor function, academic skills and aspects of adaptive behaviour, though within age expectations. Lower Full-Scale IQ and Processing Speed were associated with higher IA in CHEU and lower adaptive functioning with higher IA in CHUU. Across both groups, children of unemployed mothers had more HI symptoms. CHEU were not at increased risk for attention difficulties at 5.5 years of age. Maternal employment status highlights the contribution of sociodemographic factors in shaping behaviour and neurodevelopment. [ABSTRACT FROM AUTHOR]
Copyright of AIDS Care is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Attention and neurodevelopment in young children who are HIV-exposed uninfected.
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  Data: <searchLink fieldCode="AR" term="%22Young%2C+Julia+M%2E%22">Young, Julia M.</searchLink><br /><searchLink fieldCode="AR" term="%22Chen%2C+Vanessa%22">Chen, Vanessa</searchLink><br /><searchLink fieldCode="AR" term="%22Bitnun%2C+Ari%22">Bitnun, Ari</searchLink><br /><searchLink fieldCode="AR" term="%22Read%2C+Stanley+E%2E%22">Read, Stanley E.</searchLink><br /><searchLink fieldCode="AR" term="%22Smith%2C+Mary+Lou%22">Smith, Mary Lou</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22AIDS+Care%22">AIDS Care</searchLink>. Jan2024, Vol. 36 Issue 1, p26-35. 10p.
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  Data: <searchLink fieldCode="DE" term="%22Education+of+mothers%22">Education of mothers</searchLink><br /><searchLink fieldCode="DE" term="%22HIV+infections%22">HIV infections</searchLink><br /><searchLink fieldCode="DE" term="%22Multiple+regression+analysis%22">Multiple regression analysis</searchLink><br /><searchLink fieldCode="DE" term="%22Developmental+disabilities%22">Developmental disabilities</searchLink><br /><searchLink fieldCode="DE" term="%22Neural+development%22">Neural development</searchLink><br /><searchLink fieldCode="DE" term="%22Attention%22">Attention</searchLink><br /><searchLink fieldCode="DE" term="%22Infectious+disease+transmission%22">Infectious disease transmission</searchLink><br /><searchLink fieldCode="DE" term="%22Intellect%22">Intellect</searchLink><br /><searchLink fieldCode="DE" term="%22Employment%22">Employment</searchLink><br /><searchLink fieldCode="DE" term="%22Research+funding%22">Research funding</searchLink><br /><searchLink fieldCode="DE" term="%22Children%22">Children</searchLink>
– Name: Abstract
  Label: Abstract
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  Data: Children HIV-exposed, uninfected (CHEU) are at risk for compromised developmental outcomes. Attention is important for behavioural, cognitive and academic skills, yet has not been thoroughly investigated compared to children HIV-unexposed uninfected (CHUU). Fifty-five CHEU and 51 CHUU children were recruited at 5.5 years of age. Measures of inattention (IA), hyperactivity/impulsivity (HI) and total scores were collected using the parent-reported ADHD-Rating-Scale-IV. Measures of intelligence, visuomotor skills, academics and adaptive functioning were obtained. Analyses of between-group differences were performed as were correlational and multiple regression models, accounting for maternal education, employment and delivery type. Few children met clinical cut-offs for probable ADHD (3.6% CHEU, 2.0% CHUU), and no group differences in measures of IA, HI and combined scores were found. CHEU scored significantly lower than CHUU on intelligence, visuomotor function, academic skills and aspects of adaptive behaviour, though within age expectations. Lower Full-Scale IQ and Processing Speed were associated with higher IA in CHEU and lower adaptive functioning with higher IA in CHUU. Across both groups, children of unemployed mothers had more HI symptoms. CHEU were not at increased risk for attention difficulties at 5.5 years of age. Maternal employment status highlights the contribution of sociodemographic factors in shaping behaviour and neurodevelopment. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
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  Data: <i>Copyright of AIDS Care is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
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    Identifiers:
      – Type: doi
        Value: 10.1080/09540121.2023.2240069
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      – Code: eng
        Text: English
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        PageCount: 10
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    Subjects:
      – SubjectFull: Education of mothers
        Type: general
      – SubjectFull: HIV infections
        Type: general
      – SubjectFull: Multiple regression analysis
        Type: general
      – SubjectFull: Developmental disabilities
        Type: general
      – SubjectFull: Neural development
        Type: general
      – SubjectFull: Attention
        Type: general
      – SubjectFull: Infectious disease transmission
        Type: general
      – SubjectFull: Intellect
        Type: general
      – SubjectFull: Employment
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      – SubjectFull: Research funding
        Type: general
      – SubjectFull: Children
        Type: general
    Titles:
      – TitleFull: Attention and neurodevelopment in young children who are HIV-exposed uninfected.
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            NameFull: Young, Julia M.
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            NameFull: Chen, Vanessa
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            NameFull: Bitnun, Ari
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            NameFull: Read, Stanley E.
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              Text: Jan2024
              Type: published
              Y: 2024
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              Value: 36
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