HIV epidemiology, prevention, treatment, and implementation strategies for public health.

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Title: HIV epidemiology, prevention, treatment, and implementation strategies for public health.
Authors: Mody, Aaloke (AUTHOR), Sohn, Annette H (AUTHOR), Iwuji, Collins (AUTHOR), Tan, Rayner K J (AUTHOR), Venter, Francois (AUTHOR), Geng, Elvin H (AUTHOR)
Source: Lancet. Feb2024, Vol. 403 Issue 10425, p471-492. 22p.
Subjects: HIV, HIV prevention, Public health, General practitioners, Epidemiology
Abstract: The global HIV response has made tremendous progress but is entering a new phase with additional challenges. Scientific innovations have led to multiple safe, effective, and durable options for treatment and prevention, and long-acting formulations for 2-monthly and 6-monthly dosing are becoming available with even longer dosing intervals possible on the horizon. The scientific agenda for HIV cure and remission strategies is moving forward but faces uncertain thresholds for success and acceptability. Nonetheless, innovations in prevention and treatment have often failed to reach large segments of the global population (eg, key and marginalised populations), and these major disparities in access and uptake at multiple levels have caused progress to fall short of their potential to affect public health. Moving forward, sharper epidemiologic tools based on longitudinal, person-centred data are needed to more accurately characterise remaining gaps and guide continued progress against the HIV epidemic. We should also increase prioritisation of strategies that address socio-behavioural challenges and can lead to effective and equitable implementation of existing interventions with high levels of quality that better match individual needs. We review HIV epidemiologic trends; advances in HIV prevention, treatment, and care delivery; and discuss emerging challenges for ending the HIV epidemic over the next decade that are relevant for general practitioners and others involved in HIV care. [ABSTRACT FROM AUTHOR]
Copyright of Lancet is the property of Lancet and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: HIV epidemiology, prevention, treatment, and implementation strategies for public health.
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  Data: <searchLink fieldCode="AR" term="%22Mody%2C+Aaloke%22">Mody, Aaloke</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Sohn%2C+Annette+H%22">Sohn, Annette H</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Iwuji%2C+Collins%22">Iwuji, Collins</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Tan%2C+Rayner+K+J%22">Tan, Rayner K J</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Venter%2C+Francois%22">Venter, Francois</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Geng%2C+Elvin+H%22">Geng, Elvin H</searchLink> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22Lancet%22">Lancet</searchLink>. Feb2024, Vol. 403 Issue 10425, p471-492. 22p.
– Name: Subject
  Label: Subjects
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  Data: <searchLink fieldCode="DE" term="%22HIV%22">HIV</searchLink><br /><searchLink fieldCode="DE" term="%22HIV+prevention%22">HIV prevention</searchLink><br /><searchLink fieldCode="DE" term="%22Public+health%22">Public health</searchLink><br /><searchLink fieldCode="DE" term="%22General+practitioners%22">General practitioners</searchLink><br /><searchLink fieldCode="DE" term="%22Epidemiology%22">Epidemiology</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: The global HIV response has made tremendous progress but is entering a new phase with additional challenges. Scientific innovations have led to multiple safe, effective, and durable options for treatment and prevention, and long-acting formulations for 2-monthly and 6-monthly dosing are becoming available with even longer dosing intervals possible on the horizon. The scientific agenda for HIV cure and remission strategies is moving forward but faces uncertain thresholds for success and acceptability. Nonetheless, innovations in prevention and treatment have often failed to reach large segments of the global population (eg, key and marginalised populations), and these major disparities in access and uptake at multiple levels have caused progress to fall short of their potential to affect public health. Moving forward, sharper epidemiologic tools based on longitudinal, person-centred data are needed to more accurately characterise remaining gaps and guide continued progress against the HIV epidemic. We should also increase prioritisation of strategies that address socio-behavioural challenges and can lead to effective and equitable implementation of existing interventions with high levels of quality that better match individual needs. We review HIV epidemiologic trends; advances in HIV prevention, treatment, and care delivery; and discuss emerging challenges for ending the HIV epidemic over the next decade that are relevant for general practitioners and others involved in HIV care. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
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  Data: <i>Copyright of Lancet is the property of Lancet and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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      – Type: doi
        Value: 10.1016/S0140-6736(23)01381-8
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      – Code: eng
        Text: English
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      – SubjectFull: HIV
        Type: general
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      – SubjectFull: Public health
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      – SubjectFull: General practitioners
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      – SubjectFull: Epidemiology
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              Text: Feb2024
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              Y: 2024
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