Office‐based vergence and anti‐suppression therapy for the treatment of small‐to‐moderate angle intermittent exotropia: A randomised clinical trial.
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| Title: | Office‐based vergence and anti‐suppression therapy for the treatment of small‐to‐moderate angle intermittent exotropia: A randomised clinical trial. |
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| Authors: | Ma, Martin Ming‐Leung (AUTHOR), Kang, Ying (AUTHOR), Scheiman, Mitchell (AUTHOR), Chen, Qiwen (AUTHOR), Ye, Xuelian (AUTHOR), Pan, Liuqing (AUTHOR), Deng, Jiayu (AUTHOR), Su, Guangxing (AUTHOR), Zhang, Guohui (AUTHOR), Chen, Xiang (AUTHOR) |
| Source: | Ophthalmic & Physiological Optics. Mar2024, Vol. 44 Issue 2, p356-377. 22p. |
| Abstract: | Purpose: To evaluate the short‐term (1 week after completion of treatment) effect of office‐based vergence and anti‐suppression therapy (OBVAT) on the Office Control Score when compared to observation alone in children with small‐to‐moderate angle intermittent exotropia (IXT). Methods: In this single‐masked (examiner masked), two‐arm, single‐centre randomised clinical trial, 40 participants, 6 to <18 years of age with untreated IXT, were randomly assigned to OBVAT or observation alone. Participants assigned to therapy received 60 min of OBVAT with home reinforcement once per week for 16 weeks. Therapy included vergence, accommodation and anti‐suppression techniques. The primary outcome measure was the comparison of the distance Office Control Score between the two groups at the primary outcome visit (i.e., 17‐week follow‐up visit). Results: At the primary outcome visit, the OBVAT group (n = 20) had a significantly better distance Office Control Score (adjusted mean difference: −0.9; 95% CI: −0.2 to −1.5; p = 0.008; partial eta squared: 0.19) than the observation group (n = 16). Participants from the OBVAT group were more likely than those from the observation group to have ≥1 point of improvement at the 17‐week visit (OBVAT group: 75%; Observation group: 25%; p = 0.006). Conclusions: In this randomised clinical trial of participants aged 6 to <18 years with IXT, we found that the OBVAT group had a significantly better distance Office Control Score than the observation group at the 17‐week visit. This study provides the first data from a randomised clinical trial demonstrating the effectiveness of OBVAT for improving the control of IXT. Eye care practitioners should consider OBVAT as a viable, non‐surgical treatment option for IXT. A full‐scale randomised clinical trial investigating the long‐term effectiveness of OBVAT in treating IXT is warranted. [ABSTRACT FROM AUTHOR] |
| Copyright of Ophthalmic & Physiological Optics is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 175305041 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Office‐based vergence and anti‐suppression therapy for the treatment of small‐to‐moderate angle intermittent exotropia: A randomised clinical trial. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Ma%2C+Martin+Ming‐Leung%22">Ma, Martin Ming‐Leung</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kang%2C+Ying%22">Kang, Ying</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Scheiman%2C+Mitchell%22">Scheiman, Mitchell</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Chen%2C+Qiwen%22">Chen, Qiwen</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Ye%2C+Xuelian%22">Ye, Xuelian</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Pan%2C+Liuqing%22">Pan, Liuqing</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Deng%2C+Jiayu%22">Deng, Jiayu</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Su%2C+Guangxing%22">Su, Guangxing</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Zhang%2C+Guohui%22">Zhang, Guohui</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Chen%2C+Xiang%22">Chen, Xiang</searchLink> (AUTHOR) – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Ophthalmic+%26+Physiological+Optics%22">Ophthalmic & Physiological Optics</searchLink>. Mar2024, Vol. 44 Issue 2, p356-377. 22p. – Name: Abstract Label: Abstract Group: Ab Data: Purpose: To evaluate the short‐term (1 week after completion of treatment) effect of office‐based vergence and anti‐suppression therapy (OBVAT) on the Office Control Score when compared to observation alone in children with small‐to‐moderate angle intermittent exotropia (IXT). Methods: In this single‐masked (examiner masked), two‐arm, single‐centre randomised clinical trial, 40 participants, 6 to <18 years of age with untreated IXT, were randomly assigned to OBVAT or observation alone. Participants assigned to therapy received 60 min of OBVAT with home reinforcement once per week for 16 weeks. Therapy included vergence, accommodation and anti‐suppression techniques. The primary outcome measure was the comparison of the distance Office Control Score between the two groups at the primary outcome visit (i.e., 17‐week follow‐up visit). Results: At the primary outcome visit, the OBVAT group (n = 20) had a significantly better distance Office Control Score (adjusted mean difference: −0.9; 95% CI: −0.2 to −1.5; p = 0.008; partial eta squared: 0.19) than the observation group (n = 16). Participants from the OBVAT group were more likely than those from the observation group to have ≥1 point of improvement at the 17‐week visit (OBVAT group: 75%; Observation group: 25%; p = 0.006). Conclusions: In this randomised clinical trial of participants aged 6 to <18 years with IXT, we found that the OBVAT group had a significantly better distance Office Control Score than the observation group at the 17‐week visit. This study provides the first data from a randomised clinical trial demonstrating the effectiveness of OBVAT for improving the control of IXT. Eye care practitioners should consider OBVAT as a viable, non‐surgical treatment option for IXT. A full‐scale randomised clinical trial investigating the long‐term effectiveness of OBVAT in treating IXT is warranted. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Ophthalmic & Physiological Optics is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1111/opo.13264 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 22 StartPage: 356 Titles: – TitleFull: Office‐based vergence and anti‐suppression therapy for the treatment of small‐to‐moderate angle intermittent exotropia: A randomised clinical trial. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Ma, Martin Ming‐Leung – PersonEntity: Name: NameFull: Kang, Ying – PersonEntity: Name: NameFull: Scheiman, Mitchell – PersonEntity: Name: NameFull: Chen, Qiwen – PersonEntity: Name: NameFull: Ye, Xuelian – PersonEntity: Name: NameFull: Pan, Liuqing – PersonEntity: Name: NameFull: Deng, Jiayu – PersonEntity: Name: NameFull: Su, Guangxing – PersonEntity: Name: NameFull: Zhang, Guohui – PersonEntity: Name: NameFull: Chen, Xiang IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 03 Text: Mar2024 Type: published Y: 2024 Identifiers: – Type: issn-print Value: 02755408 Numbering: – Type: volume Value: 44 – Type: issue Value: 2 Titles: – TitleFull: Ophthalmic & Physiological Optics Type: main |
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