Isolated pontocerebellar leukoencephalopathy in HIV-related PML: focus on the "shrimp sign".

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Title: Isolated pontocerebellar leukoencephalopathy in HIV-related PML: focus on the "shrimp sign".
Authors: Cimmino, Angelo Tiziano (AUTHOR), Carlomagno, Vincenzo (AUTHOR), Sciarrone, Maria Ausilia (AUTHOR), Di Lazzaro, Giulia (AUTHOR), Silvestri, Gabriella (AUTHOR)
Source: Neurological Sciences. Mar2024, Vol. 45 Issue 3, p1295-1298. 4p.
Subjects: John Cunningham virus, Leukoencephalopathies, Shrimps, Scientific literature, Progressive multifocal leukoencephalopathy, Neurologic examination, Central nervous system diseases
Abstract: This article describes a case study of a 67-year-old man who presented with speech and gait disturbances following an episode of gastroenteritis. The patient had cerebellar dysarthria and limb incoordination, and an MRI revealed bilateral lesions in the white matter of the brain. Further testing confirmed a diagnosis of progressive multifocal leukoencephalopathy (PML) caused by reactivation of the John Cunningham virus (JCV) in the context of HIV infection. The article discusses the typical features of PML on MRI and highlights the importance of early recognition and treatment. [Extracted from the article]
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Database: Psychology and Behavioral Sciences Collection
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Abstract:This article describes a case study of a 67-year-old man who presented with speech and gait disturbances following an episode of gastroenteritis. The patient had cerebellar dysarthria and limb incoordination, and an MRI revealed bilateral lesions in the white matter of the brain. Further testing confirmed a diagnosis of progressive multifocal leukoencephalopathy (PML) caused by reactivation of the John Cunningham virus (JCV) in the context of HIV infection. The article discusses the typical features of PML on MRI and highlights the importance of early recognition and treatment. [Extracted from the article]
ISSN:15901874
DOI:10.1007/s10072-023-07133-9