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Obesity and risk of depressive disorder in children and adolescents: A meta‐analysis of observational studies.

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Title: Obesity and risk of depressive disorder in children and adolescents: A meta‐analysis of observational studies.
Authors: Chen, Yaobing, Zhang, Jinli, Yuan, Lijun, Hu, Huifang, Li, Tianze, Zhao, Yang, Wu, Yuying, Wang, Mengmeng, Huo, Weifeng, Gao, Yajuan, Ke, Yamin, Wang, Longkang, Zhang, Wenkai, Fu, Xueru, Li, Xi, Hu, Fulan, Zhang, Ming, Sun, Liang, Hu, Dongsheng
Source: Child: Care, Health & Development. Mar2024, Vol. 50 Issue 2, p1-10. 10p.
Subjects: Mental depression risk factors, Risk assessment, Medical information storage & retrieval systems, Research funding, Meta-analysis, Systematic reviews, MEDLINE, Childhood obesity, Online information services, Confidence intervals, Sensitivity & specificity (Statistics), Mental depression, Disease complications
Abstract: Purpose: This meta‐analysis evaluated the relationship between overweight/obesity and depressive disorders in children and adolescents. Methods: We examined the databases of PubMed, Embase and Web of Science for pertinent observational studies released up until 20 February 2022. The pooled relative risks (RRs) and 95% confidence intervals (CIs) of obesity and overweight with depressive disorder were calculated by means of random‐effects models. The Newcastle‐Ottawa Quality Assessment Scale and Agency for Healthcare Research and Quality scale were adopted to evaluate the study quality. Results: Finally, for this meta‐analysis, we evaluated 22 observational publications covering 175 135 participants (5 cohort study articles, 1 case–control study article and 16 cross‐sectional study articles). A significant positive association was found between obesity and the risk of depression (RR 1.32, 95% CI 1.09–1.60, I2 = 79.90%, Pheterogeneity < 0.001) and in the association between obesity and depressive symptoms (RR 1.16, 95% CI: 1.00–1.35, I2 = 25.0%, Pheterogeneity = 0.247). On sensitivity analysis, the pooled RRs remained robust. Subgroup analysis indicated that obese children and teenagers in western countries were more prone to depression. Conclusion: Evidence from this meta‐analysis, based on observational studies, supported the idea that obese children and adolescents are more likely to experience depression and depressive symptoms. [ABSTRACT FROM AUTHOR]
Copyright of Child: Care, Health & Development is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Obesity and risk of depressive disorder in children and adolescents: A meta‐analysis of observational studies.
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  Data: Purpose: This meta‐analysis evaluated the relationship between overweight/obesity and depressive disorders in children and adolescents. Methods: We examined the databases of PubMed, Embase and Web of Science for pertinent observational studies released up until 20 February 2022. The pooled relative risks (RRs) and 95% confidence intervals (CIs) of obesity and overweight with depressive disorder were calculated by means of random‐effects models. The Newcastle‐Ottawa Quality Assessment Scale and Agency for Healthcare Research and Quality scale were adopted to evaluate the study quality. Results: Finally, for this meta‐analysis, we evaluated 22 observational publications covering 175 135 participants (5 cohort study articles, 1 case–control study article and 16 cross‐sectional study articles). A significant positive association was found between obesity and the risk of depression (RR 1.32, 95% CI 1.09–1.60, I2 = 79.90%, Pheterogeneity &lt; 0.001) and in the association between obesity and depressive symptoms (RR 1.16, 95% CI: 1.00–1.35, I2 = 25.0%, Pheterogeneity = 0.247). On sensitivity analysis, the pooled RRs remained robust. Subgroup analysis indicated that obese children and teenagers in western countries were more prone to depression. Conclusion: Evidence from this meta‐analysis, based on observational studies, supported the idea that obese children and adolescents are more likely to experience depression and depressive symptoms. [ABSTRACT FROM AUTHOR]
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  Data: &lt;i&gt;Copyright of Child: Care, Health &amp; Development is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
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        Value: 10.1111/cch.13237
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      – SubjectFull: Mental depression risk factors
        Type: general
      – SubjectFull: Risk assessment
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      – SubjectFull: Medical information storage & retrieval systems
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      – SubjectFull: Confidence intervals
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      – SubjectFull: Disease complications
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              Text: Mar2024
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