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The body of evidence of late-life depression: the complex relationship between depressive symptoms, movement, dyspnea and cognition.

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Title: The body of evidence of late-life depression: the complex relationship between depressive symptoms, movement, dyspnea and cognition.
Authors: Belvederi Murri, Martino, Triolo, Federico, Coni, Alice, Nerozzi, Erika, Maietta Latessa, Pasqualino, Fantozzi, Silvia, Padula, Nicola, Escelsior, Andrea, Assirelli, Barbara, Ermini, Giuliano, Bagnoli, Luigi, Zocchi, Donato, Cabassi, Aderville, Tedeschi, Stefano, Toni, Giulio, Chattat, Rabih, Tripi, Ferdinando, Neviani, Francesca, Bertolotti, Marco, Cremonini, Alessandro
Source: Experimental Aging Research. May/Jun2024, Vol. 50 Issue 3, p296-311. 16p.
Subjects: Sadness, Antidepressants, Muscle weakness, Cognition disorders, Aging, Research, Dyspnea, Mental depression, Physical activity, Psychosocial factors
Abstract: Physical symptoms play an important role in late-life depression and may contribute to residual symptomatology after antidepressant treatment. In this exploratory study, we examined the role of specific bodily dimensions including movement, respiratory functions, fear of falling, cognition, and physical weakness in older people with depression. Clinically stable older patients with major depression within a Psychiatric Consultation-Liaison program for Primary Care underwent comprehensive assessment of depressive symptoms, instrumental movement analysis, dyspnea, weakness, activity limitations, cognitive function, and fear of falling. Network analysis was performed to explore the unique adjusted associations between clinical dimensions. Sadness was associated with worse turning and walking ability and movement transitions from walking to sitting, as well as with worse general cognitive abilities. Sadness was also connected with dyspnea, while neurovegetative depressive burden was connected with activity limitations. Limitations of motor and cognitive function, dyspnea, and weakness may contribute to the persistence of residual symptoms of late-life depression. [ABSTRACT FROM AUTHOR]
Copyright of Experimental Aging Research is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: The body of evidence of late-life depression: the complex relationship between depressive symptoms, movement, dyspnea and cognition.
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  Data: <searchLink fieldCode="JN" term="%22Experimental+Aging+Research%22">Experimental Aging Research</searchLink>. May/Jun2024, Vol. 50 Issue 3, p296-311. 16p.
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  Data: <searchLink fieldCode="DE" term="%22Sadness%22">Sadness</searchLink><br /><searchLink fieldCode="DE" term="%22Antidepressants%22">Antidepressants</searchLink><br /><searchLink fieldCode="DE" term="%22Muscle+weakness%22">Muscle weakness</searchLink><br /><searchLink fieldCode="DE" term="%22Cognition+disorders%22">Cognition disorders</searchLink><br /><searchLink fieldCode="DE" term="%22Aging%22">Aging</searchLink><br /><searchLink fieldCode="DE" term="%22Research%22">Research</searchLink><br /><searchLink fieldCode="DE" term="%22Dyspnea%22">Dyspnea</searchLink><br /><searchLink fieldCode="DE" term="%22Mental+depression%22">Mental depression</searchLink><br /><searchLink fieldCode="DE" term="%22Physical+activity%22">Physical activity</searchLink><br /><searchLink fieldCode="DE" term="%22Psychosocial+factors%22">Psychosocial factors</searchLink>
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  Label: Abstract
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  Data: Physical symptoms play an important role in late-life depression and may contribute to residual symptomatology after antidepressant treatment. In this exploratory study, we examined the role of specific bodily dimensions including movement, respiratory functions, fear of falling, cognition, and physical weakness in older people with depression. Clinically stable older patients with major depression within a Psychiatric Consultation-Liaison program for Primary Care underwent comprehensive assessment of depressive symptoms, instrumental movement analysis, dyspnea, weakness, activity limitations, cognitive function, and fear of falling. Network analysis was performed to explore the unique adjusted associations between clinical dimensions. Sadness was associated with worse turning and walking ability and movement transitions from walking to sitting, as well as with worse general cognitive abilities. Sadness was also connected with dyspnea, while neurovegetative depressive burden was connected with activity limitations. Limitations of motor and cognitive function, dyspnea, and weakness may contribute to the persistence of residual symptoms of late-life depression. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Experimental Aging Research is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1080/0361073X.2023.2196504
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      – Code: eng
        Text: English
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        PageCount: 16
        StartPage: 296
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      – SubjectFull: Sadness
        Type: general
      – SubjectFull: Antidepressants
        Type: general
      – SubjectFull: Muscle weakness
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      – SubjectFull: Aging
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      – SubjectFull: Mental depression
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              Text: May/Jun2024
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