Independent and joint contributions of physical disability and chronic pain to incident opioid use disorder and opioid overdose among Medicaid patients.

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Title: Independent and joint contributions of physical disability and chronic pain to incident opioid use disorder and opioid overdose among Medicaid patients.
Authors: Hoffman, Katherine L., Milazzo, Floriana, Williams, Nicholas T., Samples, Hillary, Olfson, Mark, Diaz, Ivan, Doan, Lisa, Cerda, Magdalena, Crystal, Stephen, Rudolph, Kara E.
Source: Psychological Medicine. May2024, Vol. 54 Issue 7, p1419-1430. 12p.
Subjects: Substance abuse risk factors, Drug overdose, Chronic pain, Research funding, Descriptive statistics, Treatment effectiveness, Attention, Opioid analgesics, Physician practice patterns, Medicaid, Drug prescribing, People with disabilities, Comorbidity, Patient aftercare, Disease risk factors, Disease complications
Abstract: Background: Chronic pain has been extensively explored as a risk factor for opioid misuse, resulting in increased focus on opioid prescribing practices for individuals with such conditions. Physical disability sometimes co-occurs with chronic pain but may also represent an independent risk factor for opioid misuse. However, previous research has not disentangled whether disability contributes to risk independent of chronic pain. Methods: Here, we estimate the independent and joint adjusted associations between having a physical disability and co-occurring chronic pain condition at time of Medicaid enrollment on subsequent 18-month risk of incident opioid use disorder (OUD) and non-fatal, unintentional opioid overdose among non-elderly, adult Medicaid beneficiaries (2016–2019). Results: We find robust evidence that having a physical disability approximately doubles the risk of incident OUD or opioid overdose, and physical disability co-occurring with chronic pain increases the risks approximately sixfold as compared to having neither chronic pain nor disability. In absolute numbers, those with neither a physical disability nor chronic pain condition have a 1.8% adjusted risk of incident OUD over 18 months of follow-up, those with physical disability alone have an 2.9% incident risk, those with chronic pain alone have a 3.6% incident risk, and those with co-occurring physical disability and chronic pain have a 11.1% incident risk. Conclusions: These findings suggest that those with a physical disability should receive increased attention from the medical and healthcare communities to reduce their risk of opioid misuse and attendant negative outcomes. [ABSTRACT FROM AUTHOR]
Copyright of Psychological Medicine is the property of Cambridge University Press and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Independent and joint contributions of physical disability and chronic pain to incident opioid use disorder and opioid overdose among Medicaid patients.
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  Data: <searchLink fieldCode="AR" term="%22Hoffman%2C+Katherine+L%2E%22">Hoffman, Katherine L.</searchLink><br /><searchLink fieldCode="AR" term="%22Milazzo%2C+Floriana%22">Milazzo, Floriana</searchLink><br /><searchLink fieldCode="AR" term="%22Williams%2C+Nicholas+T%2E%22">Williams, Nicholas T.</searchLink><br /><searchLink fieldCode="AR" term="%22Samples%2C+Hillary%22">Samples, Hillary</searchLink><br /><searchLink fieldCode="AR" term="%22Olfson%2C+Mark%22">Olfson, Mark</searchLink><br /><searchLink fieldCode="AR" term="%22Diaz%2C+Ivan%22">Diaz, Ivan</searchLink><br /><searchLink fieldCode="AR" term="%22Doan%2C+Lisa%22">Doan, Lisa</searchLink><br /><searchLink fieldCode="AR" term="%22Cerda%2C+Magdalena%22">Cerda, Magdalena</searchLink><br /><searchLink fieldCode="AR" term="%22Crystal%2C+Stephen%22">Crystal, Stephen</searchLink><br /><searchLink fieldCode="AR" term="%22Rudolph%2C+Kara+E%2E%22">Rudolph, Kara E.</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22Psychological+Medicine%22">Psychological Medicine</searchLink>. May2024, Vol. 54 Issue 7, p1419-1430. 12p.
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  Data: <searchLink fieldCode="DE" term="%22Substance+abuse+risk+factors%22">Substance abuse risk factors</searchLink><br /><searchLink fieldCode="DE" term="%22Drug+overdose%22">Drug overdose</searchLink><br /><searchLink fieldCode="DE" term="%22Chronic+pain%22">Chronic pain</searchLink><br /><searchLink fieldCode="DE" term="%22Research+funding%22">Research funding</searchLink><br /><searchLink fieldCode="DE" term="%22Descriptive+statistics%22">Descriptive statistics</searchLink><br /><searchLink fieldCode="DE" term="%22Treatment+effectiveness%22">Treatment effectiveness</searchLink><br /><searchLink fieldCode="DE" term="%22Attention%22">Attention</searchLink><br /><searchLink fieldCode="DE" term="%22Opioid+analgesics%22">Opioid analgesics</searchLink><br /><searchLink fieldCode="DE" term="%22Physician+practice+patterns%22">Physician practice patterns</searchLink><br /><searchLink fieldCode="DE" term="%22Medicaid%22">Medicaid</searchLink><br /><searchLink fieldCode="DE" term="%22Drug+prescribing%22">Drug prescribing</searchLink><br /><searchLink fieldCode="DE" term="%22People+with+disabilities%22">People with disabilities</searchLink><br /><searchLink fieldCode="DE" term="%22Comorbidity%22">Comorbidity</searchLink><br /><searchLink fieldCode="DE" term="%22Patient+aftercare%22">Patient aftercare</searchLink><br /><searchLink fieldCode="DE" term="%22Disease+risk+factors%22">Disease risk factors</searchLink><br /><searchLink fieldCode="DE" term="%22Disease+complications%22">Disease complications</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Background: Chronic pain has been extensively explored as a risk factor for opioid misuse, resulting in increased focus on opioid prescribing practices for individuals with such conditions. Physical disability sometimes co-occurs with chronic pain but may also represent an independent risk factor for opioid misuse. However, previous research has not disentangled whether disability contributes to risk independent of chronic pain. Methods: Here, we estimate the independent and joint adjusted associations between having a physical disability and co-occurring chronic pain condition at time of Medicaid enrollment on subsequent 18-month risk of incident opioid use disorder (OUD) and non-fatal, unintentional opioid overdose among non-elderly, adult Medicaid beneficiaries (2016–2019). Results: We find robust evidence that having a physical disability approximately doubles the risk of incident OUD or opioid overdose, and physical disability co-occurring with chronic pain increases the risks approximately sixfold as compared to having neither chronic pain nor disability. In absolute numbers, those with neither a physical disability nor chronic pain condition have a 1.8% adjusted risk of incident OUD over 18 months of follow-up, those with physical disability alone have an 2.9% incident risk, those with chronic pain alone have a 3.6% incident risk, and those with co-occurring physical disability and chronic pain have a 11.1% incident risk. Conclusions: These findings suggest that those with a physical disability should receive increased attention from the medical and healthcare communities to reduce their risk of opioid misuse and attendant negative outcomes. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
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  Group: Ab
  Data: <i>Copyright of Psychological Medicine is the property of Cambridge University Press and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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      – Type: doi
        Value: 10.1017/S003329172300332X
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      – Code: eng
        Text: English
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      Pagination:
        PageCount: 12
        StartPage: 1419
    Subjects:
      – SubjectFull: Substance abuse risk factors
        Type: general
      – SubjectFull: Drug overdose
        Type: general
      – SubjectFull: Chronic pain
        Type: general
      – SubjectFull: Research funding
        Type: general
      – SubjectFull: Descriptive statistics
        Type: general
      – SubjectFull: Treatment effectiveness
        Type: general
      – SubjectFull: Attention
        Type: general
      – SubjectFull: Opioid analgesics
        Type: general
      – SubjectFull: Physician practice patterns
        Type: general
      – SubjectFull: Medicaid
        Type: general
      – SubjectFull: Drug prescribing
        Type: general
      – SubjectFull: People with disabilities
        Type: general
      – SubjectFull: Comorbidity
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      – SubjectFull: Patient aftercare
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      – SubjectFull: Disease risk factors
        Type: general
      – SubjectFull: Disease complications
        Type: general
    Titles:
      – TitleFull: Independent and joint contributions of physical disability and chronic pain to incident opioid use disorder and opioid overdose among Medicaid patients.
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              Text: May2024
              Type: published
              Y: 2024
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