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Effectiveness of an intervention to improve ART adherence among men who have sex with men living with HIV: a randomized controlled trial in three public HIV clinics in Mexico.

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Title: Effectiveness of an intervention to improve ART adherence among men who have sex with men living with HIV: a randomized controlled trial in three public HIV clinics in Mexico.
Authors: Andrade-Romo, Zafiro, La Hera-Fuentes, Gina, Ochoa-Sánchez, Luz Edith, Chavira-Razo, Laura, Aramburo-Muro, Tania, Castro-León, Lorena, Amaya-Tapia, Gerardo, Andrade-Pérez, Jorge Santiago, Bautista-Arredondo, Sergio
Source: AIDS Care. Jun2024, Vol. 36 Issue 6, p816-831. 16p.
Subjects: Alcoholism treatment, Substance abuse treatment, Clinical drug trials, Patient compliance, Self-evaluation, Behavior modification, Viral load, Research funding, Evaluation of human services programs, Statistical sampling, HIV-positive persons, CD4 lymphocyte count, HIV infections, Randomized controlled trials, Descriptive statistics, Men who have sex with men, Longitudinal method, Control groups, Pre-tests & post-tests, Health behavior, Anti-HIV agents, Health promotion, Comparative studies, Mental depression
Geographic Terms: Mexico
Abstract: We conducted a parallel-group randomized controlled trial in three HIV clinics in Mexico to evaluate a user-centred habit-formation intervention to improve ART adherence among MSM living with HIV. We randomized 74 participants to the intervention group and 77 to the control group. We measured adherence at one, four, and ten months through medication possession ratio and self-reported adherence. Additionally, we measured viral load, CD4 cell count, major depression disorder symptoms, and alcohol and substance use disorder at baseline, fourth and tenth months. We found no statistically significant effect on adherence between groups. However, the intervention demonstrated positive results in major depression disorder symptoms (21% vs. 6%, p = 0.008) and substance use disorder (11% vs. 1%, p = 0.018) in the fourth month. The latter is relevant because, in addition to its direct benefit, it might also improve the chances of maintaining adequate adherence in the long term. This trial was retrospectively registered at ClinicalTrials.gov (trial number NCT03410680) on 8 January 2018. Trial registration: ClinicalTrials.gov identifier: NCT03410680. [ABSTRACT FROM AUTHOR]
Copyright of AIDS Care is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Effectiveness of an intervention to improve ART adherence among men who have sex with men living with HIV: a randomized controlled trial in three public HIV clinics in Mexico.
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  Data: <searchLink fieldCode="AR" term="%22Andrade-Romo%2C+Zafiro%22">Andrade-Romo, Zafiro</searchLink><br /><searchLink fieldCode="AR" term="%22La+Hera-Fuentes%2C+Gina%22">La Hera-Fuentes, Gina</searchLink><br /><searchLink fieldCode="AR" term="%22Ochoa-Sánchez%2C+Luz+Edith%22">Ochoa-Sánchez, Luz Edith</searchLink><br /><searchLink fieldCode="AR" term="%22Chavira-Razo%2C+Laura%22">Chavira-Razo, Laura</searchLink><br /><searchLink fieldCode="AR" term="%22Aramburo-Muro%2C+Tania%22">Aramburo-Muro, Tania</searchLink><br /><searchLink fieldCode="AR" term="%22Castro-León%2C+Lorena%22">Castro-León, Lorena</searchLink><br /><searchLink fieldCode="AR" term="%22Amaya-Tapia%2C+Gerardo%22">Amaya-Tapia, Gerardo</searchLink><br /><searchLink fieldCode="AR" term="%22Andrade-Pérez%2C+Jorge+Santiago%22">Andrade-Pérez, Jorge Santiago</searchLink><br /><searchLink fieldCode="AR" term="%22Bautista-Arredondo%2C+Sergio%22">Bautista-Arredondo, Sergio</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22AIDS+Care%22">AIDS Care</searchLink>. Jun2024, Vol. 36 Issue 6, p816-831. 16p.
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  Data: <searchLink fieldCode="DE" term="%22Mexico%22">Mexico</searchLink>
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  Label: Abstract
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  Data: We conducted a parallel-group randomized controlled trial in three HIV clinics in Mexico to evaluate a user-centred habit-formation intervention to improve ART adherence among MSM living with HIV. We randomized 74 participants to the intervention group and 77 to the control group. We measured adherence at one, four, and ten months through medication possession ratio and self-reported adherence. Additionally, we measured viral load, CD4 cell count, major depression disorder symptoms, and alcohol and substance use disorder at baseline, fourth and tenth months. We found no statistically significant effect on adherence between groups. However, the intervention demonstrated positive results in major depression disorder symptoms (21% vs. 6%, p = 0.008) and substance use disorder (11% vs. 1%, p = 0.018) in the fourth month. The latter is relevant because, in addition to its direct benefit, it might also improve the chances of maintaining adequate adherence in the long term. This trial was retrospectively registered at ClinicalTrials.gov (trial number NCT03410680) on 8 January 2018. Trial registration: ClinicalTrials.gov identifier: NCT03410680. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of AIDS Care is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=176763244
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1080/09540121.2023.2299322
    Languages:
      – Code: eng
        Text: English
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        PageCount: 16
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    Subjects:
      – SubjectFull: Alcoholism treatment
        Type: general
      – SubjectFull: Substance abuse treatment
        Type: general
      – SubjectFull: Clinical drug trials
        Type: general
      – SubjectFull: Patient compliance
        Type: general
      – SubjectFull: Self-evaluation
        Type: general
      – SubjectFull: Behavior modification
        Type: general
      – SubjectFull: Viral load
        Type: general
      – SubjectFull: Research funding
        Type: general
      – SubjectFull: Evaluation of human services programs
        Type: general
      – SubjectFull: Statistical sampling
        Type: general
      – SubjectFull: HIV-positive persons
        Type: general
      – SubjectFull: CD4 lymphocyte count
        Type: general
      – SubjectFull: HIV infections
        Type: general
      – SubjectFull: Randomized controlled trials
        Type: general
      – SubjectFull: Descriptive statistics
        Type: general
      – SubjectFull: Men who have sex with men
        Type: general
      – SubjectFull: Longitudinal method
        Type: general
      – SubjectFull: Control groups
        Type: general
      – SubjectFull: Pre-tests & post-tests
        Type: general
      – SubjectFull: Health behavior
        Type: general
      – SubjectFull: Anti-HIV agents
        Type: general
      – SubjectFull: Health promotion
        Type: general
      – SubjectFull: Comparative studies
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      – SubjectFull: Mental depression
        Type: general
      – SubjectFull: Mexico
        Type: general
    Titles:
      – TitleFull: Effectiveness of an intervention to improve ART adherence among men who have sex with men living with HIV: a randomized controlled trial in three public HIV clinics in Mexico.
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              M: 06
              Text: Jun2024
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              Y: 2024
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