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Cerebellar ataxia and primary Sjogren's syndrome without cerebellar degeneration: a case report.

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Title: Cerebellar ataxia and primary Sjogren's syndrome without cerebellar degeneration: a case report.
Authors: Lira e Silva, Maria Júnia (AUTHOR), Magalhães, João Eudes (AUTHOR)
Source: Neurological Sciences. Jun2024, Vol. 45 Issue 6, p2919-2922. 4p.
Subjects: Sjogren's syndrome, Cerebellar ataxia, Cerebellum degeneration, Tremor, Magnetic resonance imaging, Essential tremor, Cerebrospinal fluid
Abstract: This article reports on a case of an 86-year-old woman with primary Sjogren's syndrome (pSS) who presented with cerebellar ataxia, despite no abnormalities on magnetic resonance imaging (MRI). Cerebellar ataxia is a rare manifestation of pSS, occurring in only 1.5% of cases, and is typically accompanied by cerebellar atrophy on MRI. The patient was diagnosed with pSS based on clinical symptoms, positive Sjogren's antibodies, and an elevated erythrocyte sedimentation rate. Treatment with intravenous methylprednisolone and cyclophosphamide resulted in clinical improvement. The article also discusses other reported cases of cerebellar ataxia in pSS without cerebellar degeneration on MRI and the possible inflammatory mechanisms involved in the pathogenesis of cerebellar involvement in pSS. [Extracted from the article]
Copyright of Neurological Sciences is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Cerebellar ataxia and primary Sjogren's syndrome without cerebellar degeneration: a case report.
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  Data: <searchLink fieldCode="AR" term="%22Lira+e+Silva%2C+Maria+Júnia%22">Lira e Silva, Maria Júnia</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Magalhães%2C+João+Eudes%22">Magalhães, João Eudes</searchLink> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22Neurological+Sciences%22">Neurological Sciences</searchLink>. Jun2024, Vol. 45 Issue 6, p2919-2922. 4p.
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  Data: <searchLink fieldCode="DE" term="%22Sjogren's+syndrome%22">Sjogren's syndrome</searchLink><br /><searchLink fieldCode="DE" term="%22Cerebellar+ataxia%22">Cerebellar ataxia</searchLink><br /><searchLink fieldCode="DE" term="%22Cerebellum+degeneration%22">Cerebellum degeneration</searchLink><br /><searchLink fieldCode="DE" term="%22Tremor%22">Tremor</searchLink><br /><searchLink fieldCode="DE" term="%22Magnetic+resonance+imaging%22">Magnetic resonance imaging</searchLink><br /><searchLink fieldCode="DE" term="%22Essential+tremor%22">Essential tremor</searchLink><br /><searchLink fieldCode="DE" term="%22Cerebrospinal+fluid%22">Cerebrospinal fluid</searchLink>
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  Label: Abstract
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  Data: This article reports on a case of an 86-year-old woman with primary Sjogren's syndrome (pSS) who presented with cerebellar ataxia, despite no abnormalities on magnetic resonance imaging (MRI). Cerebellar ataxia is a rare manifestation of pSS, occurring in only 1.5% of cases, and is typically accompanied by cerebellar atrophy on MRI. The patient was diagnosed with pSS based on clinical symptoms, positive Sjogren's antibodies, and an elevated erythrocyte sedimentation rate. Treatment with intravenous methylprednisolone and cyclophosphamide resulted in clinical improvement. The article also discusses other reported cases of cerebellar ataxia in pSS without cerebellar degeneration on MRI and the possible inflammatory mechanisms involved in the pathogenesis of cerebellar involvement in pSS. [Extracted from the article]
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  Data: <i>Copyright of Neurological Sciences is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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      – Type: doi
        Value: 10.1007/s10072-024-07333-x
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        Text: English
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    Subjects:
      – SubjectFull: Sjogren's syndrome
        Type: general
      – SubjectFull: Cerebellar ataxia
        Type: general
      – SubjectFull: Cerebellum degeneration
        Type: general
      – SubjectFull: Tremor
        Type: general
      – SubjectFull: Magnetic resonance imaging
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      – SubjectFull: Essential tremor
        Type: general
      – SubjectFull: Cerebrospinal fluid
        Type: general
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      – TitleFull: Cerebellar ataxia and primary Sjogren's syndrome without cerebellar degeneration: a case report.
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              M: 06
              Text: Jun2024
              Type: published
              Y: 2024
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