Cerebellar ataxia and primary Sjogren's syndrome without cerebellar degeneration: a case report.
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| Title: | Cerebellar ataxia and primary Sjogren's syndrome without cerebellar degeneration: a case report. |
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| Authors: | Lira e Silva, Maria Júnia (AUTHOR), Magalhães, João Eudes (AUTHOR) |
| Source: | Neurological Sciences. Jun2024, Vol. 45 Issue 6, p2919-2922. 4p. |
| Subjects: | Sjogren's syndrome, Cerebellar ataxia, Cerebellum degeneration, Tremor, Magnetic resonance imaging, Essential tremor, Cerebrospinal fluid |
| Abstract: | This article reports on a case of an 86-year-old woman with primary Sjogren's syndrome (pSS) who presented with cerebellar ataxia, despite no abnormalities on magnetic resonance imaging (MRI). Cerebellar ataxia is a rare manifestation of pSS, occurring in only 1.5% of cases, and is typically accompanied by cerebellar atrophy on MRI. The patient was diagnosed with pSS based on clinical symptoms, positive Sjogren's antibodies, and an elevated erythrocyte sedimentation rate. Treatment with intravenous methylprednisolone and cyclophosphamide resulted in clinical improvement. The article also discusses other reported cases of cerebellar ataxia in pSS without cerebellar degeneration on MRI and the possible inflammatory mechanisms involved in the pathogenesis of cerebellar involvement in pSS. [Extracted from the article] |
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| Database: | Psychology and Behavioral Sciences Collection |
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