View in EDS HTML Full Text PDF Full Text

The United Kingdom Eating Disorders Genetics Initiative.

Saved in:
Bibliographic Details
Title: The United Kingdom Eating Disorders Genetics Initiative.
Authors: Monssen, Dina, Davies, Helena L., Kakar, Saakshi, Bristow, Shannon, Curzons, Susannah C. B., Davies, Molly R., Kelly, Emily J., Ahmad, Zain, Bradley, John R., Bright, Steven, Coleman, Jonathan R. I., Glen, Kiran, Hotopf, Matthew, Ter Kuile, Abigail R., Malouf, Chelsea Mika, Kalsi, Gursharan, Kingston, Nathalie, McAtarsney‐Kovacs, Monika, Mundy, Jessica, Peel, Alicia J.
Source: International Journal of Eating Disorders. May2024, Vol. 57 Issue 5, p1145-1159. 15p.
Subjects: Diagnosis of eating disorders, Saliva analysis, DNA analysis, Bulimia diagnosis, Risk assessment, Research funding, Mental illness, Questionnaires, Binge-eating disorder, Internet, Descriptive statistics, Eating disorders, Genetic risk score, Surveys, Anorexia nervosa, Sociodemographic factors, Genetic testing, Comorbidity
Geographic Terms: England, United Kingdom
Abstract: Objective: The United Kingdom Eating Disorders Genetics Initiative (EDGI UK), part of the National Institute for Health and Care Research (NIHR) Mental Health BioResource, aims to deepen our understanding of the environmental and genetic etiology of eating disorders. EDGI UK launched in February 2020 and is partnered with the UK eating disorders charity, Beat. Multiple EDGI branches exist worldwide. This article serves the dual function of providing an in‐depth description of our study protocol and of describing our initial sample including demographics, diagnoses, and physical and psychiatric comorbidities. Method: EDGI UK recruits via media and clinical services. Anyone living in England, at least 16 years old, with a lifetime probable or clinical eating disorder is eligible to sign up online: edgiuk.org. Participants complete online questionnaires, donate a saliva sample for genetic analysis, and consent to medical record linkage and recontact for future studies. Results: As of September 2022, EDGI UK recruited 7435 survey participants: 98% female, 93.1% white, 97.8% cisgender, 65.9% heterosexual, and 52.1% have a university degree. Over half (57.8%) of these participants have returned their saliva DNA kit. The most common diagnoses are anorexia nervosa (48.3%), purging disorder (37.8%), bulimia nervosa (37.5%), binge‐eating disorder (15.8%), and atypical anorexia nervosa (7.8%). Conclusion: EDGI UK is the largest UK eating disorders study and efforts to increase its diversity are underway. It offers a unique opportunity to accelerate eating disorder research. Researchers and participants with lived experience can collaborate on projects with unparalleled sample size. Public Significance Statement: Eating disorders are debilitating and costly for society but are under‐researched due to underfunding. EDGI UK is one of the largest eating disorder studies worldwide with ongoing recruitment. The collected data constitute a resource for secondary analysis. We will combine data from all international EDGI branches and the NIHR BioResource to facilitate research that improves our understanding of eating disorders and their comorbidities. [ABSTRACT FROM AUTHOR]
Copyright of International Journal of Eating Disorders is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: pbh
DbLabel: Psychology and Behavioral Sciences Collection
An: 177219733
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: The United Kingdom Eating Disorders Genetics Initiative.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Monssen%2C+Dina%22">Monssen, Dina</searchLink><br /><searchLink fieldCode="AR" term="%22Davies%2C+Helena+L%2E%22">Davies, Helena L.</searchLink><br /><searchLink fieldCode="AR" term="%22Kakar%2C+Saakshi%22">Kakar, Saakshi</searchLink><br /><searchLink fieldCode="AR" term="%22Bristow%2C+Shannon%22">Bristow, Shannon</searchLink><br /><searchLink fieldCode="AR" term="%22Curzons%2C+Susannah+C%2E+B%2E%22">Curzons, Susannah C. B.</searchLink><br /><searchLink fieldCode="AR" term="%22Davies%2C+Molly+R%2E%22">Davies, Molly R.</searchLink><br /><searchLink fieldCode="AR" term="%22Kelly%2C+Emily+J%2E%22">Kelly, Emily J.</searchLink><br /><searchLink fieldCode="AR" term="%22Ahmad%2C+Zain%22">Ahmad, Zain</searchLink><br /><searchLink fieldCode="AR" term="%22Bradley%2C+John+R%2E%22">Bradley, John R.</searchLink><br /><searchLink fieldCode="AR" term="%22Bright%2C+Steven%22">Bright, Steven</searchLink><br /><searchLink fieldCode="AR" term="%22Coleman%2C+Jonathan+R%2E+I%2E%22">Coleman, Jonathan R. I.</searchLink><br /><searchLink fieldCode="AR" term="%22Glen%2C+Kiran%22">Glen, Kiran</searchLink><br /><searchLink fieldCode="AR" term="%22Hotopf%2C+Matthew%22">Hotopf, Matthew</searchLink><br /><searchLink fieldCode="AR" term="%22Ter+Kuile%2C+Abigail+R%2E%22">Ter Kuile, Abigail R.</searchLink><br /><searchLink fieldCode="AR" term="%22Malouf%2C+Chelsea+Mika%22">Malouf, Chelsea Mika</searchLink><br /><searchLink fieldCode="AR" term="%22Kalsi%2C+Gursharan%22">Kalsi, Gursharan</searchLink><br /><searchLink fieldCode="AR" term="%22Kingston%2C+Nathalie%22">Kingston, Nathalie</searchLink><br /><searchLink fieldCode="AR" term="%22McAtarsney‐Kovacs%2C+Monika%22">McAtarsney‐Kovacs, Monika</searchLink><br /><searchLink fieldCode="AR" term="%22Mundy%2C+Jessica%22">Mundy, Jessica</searchLink><br /><searchLink fieldCode="AR" term="%22Peel%2C+Alicia+J%2E%22">Peel, Alicia J.</searchLink>
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22International+Journal+of+Eating+Disorders%22">International Journal of Eating Disorders</searchLink>. May2024, Vol. 57 Issue 5, p1145-1159. 15p.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Diagnosis+of+eating+disorders%22">Diagnosis of eating disorders</searchLink><br /><searchLink fieldCode="DE" term="%22Saliva+analysis%22">Saliva analysis</searchLink><br /><searchLink fieldCode="DE" term="%22DNA+analysis%22">DNA analysis</searchLink><br /><searchLink fieldCode="DE" term="%22Bulimia+diagnosis%22">Bulimia diagnosis</searchLink><br /><searchLink fieldCode="DE" term="%22Risk+assessment%22">Risk assessment</searchLink><br /><searchLink fieldCode="DE" term="%22Research+funding%22">Research funding</searchLink><br /><searchLink fieldCode="DE" term="%22Mental+illness%22">Mental illness</searchLink><br /><searchLink fieldCode="DE" term="%22Questionnaires%22">Questionnaires</searchLink><br /><searchLink fieldCode="DE" term="%22Binge-eating+disorder%22">Binge-eating disorder</searchLink><br /><searchLink fieldCode="DE" term="%22Internet%22">Internet</searchLink><br /><searchLink fieldCode="DE" term="%22Descriptive+statistics%22">Descriptive statistics</searchLink><br /><searchLink fieldCode="DE" term="%22Eating+disorders%22">Eating disorders</searchLink><br /><searchLink fieldCode="DE" term="%22Genetic+risk+score%22">Genetic risk score</searchLink><br /><searchLink fieldCode="DE" term="%22Surveys%22">Surveys</searchLink><br /><searchLink fieldCode="DE" term="%22Anorexia+nervosa%22">Anorexia nervosa</searchLink><br /><searchLink fieldCode="DE" term="%22Sociodemographic+factors%22">Sociodemographic factors</searchLink><br /><searchLink fieldCode="DE" term="%22Genetic+testing%22">Genetic testing</searchLink><br /><searchLink fieldCode="DE" term="%22Comorbidity%22">Comorbidity</searchLink>
– Name: SubjectGeographic
  Label: Geographic Terms
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22England%22">England</searchLink><br /><searchLink fieldCode="DE" term="%22United+Kingdom%22">United Kingdom</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Objective: The United Kingdom Eating Disorders Genetics Initiative (EDGI UK), part of the National Institute for Health and Care Research (NIHR) Mental Health BioResource, aims to deepen our understanding of the environmental and genetic etiology of eating disorders. EDGI UK launched in February 2020 and is partnered with the UK eating disorders charity, Beat. Multiple EDGI branches exist worldwide. This article serves the dual function of providing an in‐depth description of our study protocol and of describing our initial sample including demographics, diagnoses, and physical and psychiatric comorbidities. Method: EDGI UK recruits via media and clinical services. Anyone living in England, at least 16 years old, with a lifetime probable or clinical eating disorder is eligible to sign up online: edgiuk.org. Participants complete online questionnaires, donate a saliva sample for genetic analysis, and consent to medical record linkage and recontact for future studies. Results: As of September 2022, EDGI UK recruited 7435 survey participants: 98% female, 93.1% white, 97.8% cisgender, 65.9% heterosexual, and 52.1% have a university degree. Over half (57.8%) of these participants have returned their saliva DNA kit. The most common diagnoses are anorexia nervosa (48.3%), purging disorder (37.8%), bulimia nervosa (37.5%), binge‐eating disorder (15.8%), and atypical anorexia nervosa (7.8%). Conclusion: EDGI UK is the largest UK eating disorders study and efforts to increase its diversity are underway. It offers a unique opportunity to accelerate eating disorder research. Researchers and participants with lived experience can collaborate on projects with unparalleled sample size. Public Significance Statement: Eating disorders are debilitating and costly for society but are under‐researched due to underfunding. EDGI UK is one of the largest eating disorder studies worldwide with ongoing recruitment. The collected data constitute a resource for secondary analysis. We will combine data from all international EDGI branches and the NIHR BioResource to facilitate research that improves our understanding of eating disorders and their comorbidities. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of International Journal of Eating Disorders is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=177219733
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1002/eat.24037
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 15
        StartPage: 1145
    Subjects:
      – SubjectFull: Diagnosis of eating disorders
        Type: general
      – SubjectFull: Saliva analysis
        Type: general
      – SubjectFull: DNA analysis
        Type: general
      – SubjectFull: Bulimia diagnosis
        Type: general
      – SubjectFull: Risk assessment
        Type: general
      – SubjectFull: Research funding
        Type: general
      – SubjectFull: Mental illness
        Type: general
      – SubjectFull: Questionnaires
        Type: general
      – SubjectFull: Binge-eating disorder
        Type: general
      – SubjectFull: Internet
        Type: general
      – SubjectFull: Descriptive statistics
        Type: general
      – SubjectFull: Eating disorders
        Type: general
      – SubjectFull: Genetic risk score
        Type: general
      – SubjectFull: Surveys
        Type: general
      – SubjectFull: Anorexia nervosa
        Type: general
      – SubjectFull: Sociodemographic factors
        Type: general
      – SubjectFull: Genetic testing
        Type: general
      – SubjectFull: Comorbidity
        Type: general
      – SubjectFull: England
        Type: general
      – SubjectFull: United Kingdom
        Type: general
    Titles:
      – TitleFull: The United Kingdom Eating Disorders Genetics Initiative.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Monssen, Dina
      – PersonEntity:
          Name:
            NameFull: Davies, Helena L.
      – PersonEntity:
          Name:
            NameFull: Kakar, Saakshi
      – PersonEntity:
          Name:
            NameFull: Bristow, Shannon
      – PersonEntity:
          Name:
            NameFull: Curzons, Susannah C. B.
      – PersonEntity:
          Name:
            NameFull: Davies, Molly R.
      – PersonEntity:
          Name:
            NameFull: Kelly, Emily J.
      – PersonEntity:
          Name:
            NameFull: Ahmad, Zain
      – PersonEntity:
          Name:
            NameFull: Bradley, John R.
      – PersonEntity:
          Name:
            NameFull: Bright, Steven
      – PersonEntity:
          Name:
            NameFull: Coleman, Jonathan R. I.
      – PersonEntity:
          Name:
            NameFull: Glen, Kiran
      – PersonEntity:
          Name:
            NameFull: Hotopf, Matthew
      – PersonEntity:
          Name:
            NameFull: Ter Kuile, Abigail R.
      – PersonEntity:
          Name:
            NameFull: Malouf, Chelsea Mika
      – PersonEntity:
          Name:
            NameFull: Kalsi, Gursharan
      – PersonEntity:
          Name:
            NameFull: Kingston, Nathalie
      – PersonEntity:
          Name:
            NameFull: McAtarsney‐Kovacs, Monika
      – PersonEntity:
          Name:
            NameFull: Mundy, Jessica
      – PersonEntity:
          Name:
            NameFull: Peel, Alicia J.
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 05
              Text: May2024
              Type: published
              Y: 2024
          Identifiers:
            – Type: issn-print
              Value: 02763478
          Numbering:
            – Type: volume
              Value: 57
            – Type: issue
              Value: 5
          Titles:
            – TitleFull: International Journal of Eating Disorders
              Type: main
ResultId 1