Multidirectional Intervention of Chinese Herbal Medicine in the Prevention and Treatment of Atherosclerosis: From Endothelial Protection to Immunomodulation.
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| Title: | Multidirectional Intervention of Chinese Herbal Medicine in the Prevention and Treatment of Atherosclerosis: From Endothelial Protection to Immunomodulation. |
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| Authors: | Li, Jia-Ni (AUTHOR), Wang, Meng-Yu (AUTHOR), Tan, Yu-Rong (AUTHOR), Wang, Li-Li (AUTHOR) |
| Source: | American Journal of Chinese Medicine. 2024, Vol. 52 Issue 4, p925-947. 23p. |
| Subjects: | Atherosclerosis prevention, Chinese medicine, Cardiovascular diseases, Herbal medicine, Lipids, Apoptosis, Endothelium, Oxidative stress, Treatment effectiveness, Immune system, Atherosclerosis, Small molecules, Blood circulation, Inflammation, Immunity, Therapeutics |
| Abstract: | Atherosclerosis is a significant risk factor for developing cardiovascular disease and a leading cause of death worldwide. The occurrence of atherosclerosis is closely related to factors such as endothelial injury, lipid deposition, immunity, and inflammation. Conventional statins, currently used in atherosclerosis treatment, have numerous adverse side effects that limit their clinical utility, prompting the urgent need to identify safer and more effective therapeutic alternatives. Growing evidence indicates the significant potential of Chinese herbs in atherosclerosis treatment. Herbal monomer components, such as natural flavonoid compounds extracted from herbs like Coptis chinensis and Panax notoginseng, have been utilized for their lipid-lowering and inflammation-inhibiting effects in atherosclerosis treatment. These herbs can be used as single components in treating diseases and with other Chinese medicines to form herbal combinations. This approach targets the disease mechanism in multiple ways, enhancing the therapeutic effects. Thus, this review examines the roles of Chinese herbal medicine monomers and Chinese herbal compounds in inhibiting atherosclerosis, including regulating lipids, improving endothelial function, reducing oxidative stress, regulating inflammation and the immune response, and apoptosis. By highlighting these roles, our study offers new perspectives on atherosclerosis treatment with Chinese herbs and is anticipated to contribute to advancements in related research fields. [ABSTRACT FROM AUTHOR] |
| Copyright of American Journal of Chinese Medicine is the property of World Scientific Publishing Company and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 178279141 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Multidirectional Intervention of Chinese Herbal Medicine in the Prevention and Treatment of Atherosclerosis: From Endothelial Protection to Immunomodulation. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Li%2C+Jia-Ni%22">Li, Jia-Ni</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Wang%2C+Meng-Yu%22">Wang, Meng-Yu</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Tan%2C+Yu-Rong%22">Tan, Yu-Rong</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Wang%2C+Li-Li%22">Wang, Li-Li</searchLink> (AUTHOR) – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22American+Journal+of+Chinese+Medicine%22">American Journal of Chinese Medicine</searchLink>. 2024, Vol. 52 Issue 4, p925-947. 23p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Atherosclerosis+prevention%22">Atherosclerosis prevention</searchLink><br /><searchLink fieldCode="DE" term="%22Chinese+medicine%22">Chinese medicine</searchLink><br /><searchLink fieldCode="DE" term="%22Cardiovascular+diseases%22">Cardiovascular diseases</searchLink><br /><searchLink fieldCode="DE" term="%22Herbal+medicine%22">Herbal medicine</searchLink><br /><searchLink fieldCode="DE" term="%22Lipids%22">Lipids</searchLink><br /><searchLink fieldCode="DE" term="%22Apoptosis%22">Apoptosis</searchLink><br /><searchLink fieldCode="DE" term="%22Endothelium%22">Endothelium</searchLink><br /><searchLink fieldCode="DE" term="%22Oxidative+stress%22">Oxidative stress</searchLink><br /><searchLink fieldCode="DE" term="%22Treatment+effectiveness%22">Treatment effectiveness</searchLink><br /><searchLink fieldCode="DE" term="%22Immune+system%22">Immune system</searchLink><br /><searchLink fieldCode="DE" term="%22Atherosclerosis%22">Atherosclerosis</searchLink><br /><searchLink fieldCode="DE" term="%22Small+molecules%22">Small molecules</searchLink><br /><searchLink fieldCode="DE" term="%22Blood+circulation%22">Blood circulation</searchLink><br /><searchLink fieldCode="DE" term="%22Inflammation%22">Inflammation</searchLink><br /><searchLink fieldCode="DE" term="%22Immunity%22">Immunity</searchLink><br /><searchLink fieldCode="DE" term="%22Therapeutics%22">Therapeutics</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Atherosclerosis is a significant risk factor for developing cardiovascular disease and a leading cause of death worldwide. The occurrence of atherosclerosis is closely related to factors such as endothelial injury, lipid deposition, immunity, and inflammation. Conventional statins, currently used in atherosclerosis treatment, have numerous adverse side effects that limit their clinical utility, prompting the urgent need to identify safer and more effective therapeutic alternatives. Growing evidence indicates the significant potential of Chinese herbs in atherosclerosis treatment. Herbal monomer components, such as natural flavonoid compounds extracted from herbs like Coptis chinensis and Panax notoginseng, have been utilized for their lipid-lowering and inflammation-inhibiting effects in atherosclerosis treatment. These herbs can be used as single components in treating diseases and with other Chinese medicines to form herbal combinations. This approach targets the disease mechanism in multiple ways, enhancing the therapeutic effects. Thus, this review examines the roles of Chinese herbal medicine monomers and Chinese herbal compounds in inhibiting atherosclerosis, including regulating lipids, improving endothelial function, reducing oxidative stress, regulating inflammation and the immune response, and apoptosis. By highlighting these roles, our study offers new perspectives on atherosclerosis treatment with Chinese herbs and is anticipated to contribute to advancements in related research fields. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of American Journal of Chinese Medicine is the property of World Scientific Publishing Company and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1142/S0192415X24500381 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 23 StartPage: 925 Subjects: – SubjectFull: Atherosclerosis prevention Type: general – SubjectFull: Chinese medicine Type: general – SubjectFull: Cardiovascular diseases Type: general – SubjectFull: Herbal medicine Type: general – SubjectFull: Lipids Type: general – SubjectFull: Apoptosis Type: general – SubjectFull: Endothelium Type: general – SubjectFull: Oxidative stress Type: general – SubjectFull: Treatment effectiveness Type: general – SubjectFull: Immune system Type: general – SubjectFull: Atherosclerosis Type: general – SubjectFull: Small molecules Type: general – SubjectFull: Blood circulation Type: general – SubjectFull: Inflammation Type: general – SubjectFull: Immunity Type: general – SubjectFull: Therapeutics Type: general Titles: – TitleFull: Multidirectional Intervention of Chinese Herbal Medicine in the Prevention and Treatment of Atherosclerosis: From Endothelial Protection to Immunomodulation. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Li, Jia-Ni – PersonEntity: Name: NameFull: Wang, Meng-Yu – PersonEntity: Name: NameFull: Tan, Yu-Rong – PersonEntity: Name: NameFull: Wang, Li-Li IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 06 Text: 2024 Type: published Y: 2024 Identifiers: – Type: issn-print Value: 0192415X Numbering: – Type: volume Value: 52 – Type: issue Value: 4 Titles: – TitleFull: American Journal of Chinese Medicine Type: main |
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